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1.

[Serum enzyme activity in epileptic patients]. / Fermentativnaia aktivnost' syvorotki krovi u bol'nykh épilepsiei.

Pozdniakov, V S; Izotova, A E.

Zh Nevropatol Psikhiatr Im S S Korsakova ; 78(8): 1222-6, 1978.

Article in Russian | MEDLINE | ID: mdl-696112

ABSTRACT

The authors studied the activity of blood transaminase in 50 epileptic patients during different clinical periods--interattack period, prior to attacks and following different by severity paroxysms. It was found that there was increase in the transaminase activity due to the occurence of seizures. It is considered that at the basis of such changes are hemodynamical changes due to seizures and changes caused by long-term treatment with anti convulsive drugs.

Subject(s)

Alanine Transaminase/blood , Aspartate Aminotransferases/blood , Epilepsy/enzymology , Adult , Epilepsy/drug therapy , Humans , Isoenzymes , L-Lactate Dehydrogenase/blood , Middle Aged , Phenobarbital/therapeutic use

2.

[Transketolase inhibitors]. / Ingibitory transketolazy.

Kochetov, G A; Izotova, A E.

Biokhimiia ; 38(5): 954-7, 1973.

Article in Russian | MEDLINE | ID: mdl-4592477

Subject(s)

Transketolase/antagonists & inhibitors , Buffers , Enzyme Repression , Phosphates/pharmacology , Saccharomyces cerevisiae/enzymology , Spectrophotometry , Thiamine/pharmacology , Thiamine Pyrophosphate/pharmacology , Thiazoles/pharmacology

3.

[Reconstruction of holotransketolase from the apoenzyme and coenzyme]. / Rekonstruktsiia kholotransketolazy iz apofermenta i kofermenta.

Kochetov, G A; Izotova, A E.

Biokhimiia ; 38(3): 552-60, 1973.

Article in Russian | MEDLINE | ID: mdl-4592473

Subject(s)

Transketolase , Catalysis , Kinetics , Magnesium , Methods , Saccharomyces cerevisiae/enzymology , Thiamine Pyrophosphate , Transketolase/chemical synthesis

4.

[Interaction of thiamine pyrophosphate and transketolase]. / Vzaimodeistvie tiaminpirofosfata s transketolazoi.

Kochetov, G A; Izotova, A E.

Dokl Akad Nauk SSSR ; 205(4): 986-8, 1972 Aug 01.

Article in Russian | MEDLINE | ID: mdl-4564138

Subject(s)

Thiamine Pyrophosphate , Transketolase , Saccharomyces cerevisiae/enzymology

5.

The quantity of the coenzyme-binding sites in the molecule of transketolase.

Kochetov, G A; Izotova, A E; Philippov, P P; Tikhomirova, N K.

Biochem Biophys Res Commun ; 46(2): 616-20, 1972 Jan 31.

Article in English | MEDLINE | ID: mdl-4550695

Subject(s)

Saccharomyces/enzymology , Transferases , Ammonium Sulfate , Binding Sites , Chemical Precipitation , Chromatography, Gel , Enzyme Activation , Magnesium , Protein Binding , Saccharomyces cerevisiae/enzymology , Thiamine Pyrophosphate , Transketolase/isolation & purification

6.

Inhibition of transketolase by analogues of the coenzyme.

Kochetov, G A; Izotova, A E; Meshalkina, L E.

Biochem Biophys Res Commun ; 43(5): 1198-203, 1971 Jun 04.

Article in English | MEDLINE | ID: mdl-4327957

Subject(s)

Saccharomyces/enzymology , Thiamine Pyrophosphate , Transferases/antagonists & inhibitors , Animals , Binding Sites , Diphosphates , Glyceraldehyde , Glyceraldehyde-3-Phosphate Dehydrogenases , Heptoses , Kinetics , Mathematics , Muscles/enzymology , Pentosephosphates , Phosphoric Acids , Rabbits , Thiamine , Triazoles

7.

[Conditions for removal of thiamine pyrophosphate from holotransketolase]. / Usloviia otshchepleniia tiaminpirofosfata ot kholotransketolazy.

Kochetov, G A; Izotova, A E.

Biokhimiia ; 35(5): 1023-7, 1970.

Article in Russian | MEDLINE | ID: mdl-5501659

Subject(s)

Saccharomyces/enzymology , Thiamine Pyrophosphate/isolation & purification , Transferases/isolation & purification , Quaternary Ammonium Compounds

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