Predicting place of death of elderly cancer patients followed by a palliative care unit.

To determine the predictors of death outside the palliative care system for elderly cancer patients who were followed by a palliative care unit (PCU), a retrospective review of 199 charts was performed. Comorbidities, current neoplastic disease (location of tumor, months since diagnosis, number of days of PCU follow-up), symptoms, drug use, and social support were recorded. Place of death was not significantly different among sexes. Factors predicting death in the general hospital for men were digestive comorbidities, vomiting, and weakness. For women, disease of the senses was predictive. Although there were no significant differences with respect to place of death between sexes in an older cancer population followed by a PCU, the factors that predicted which patients will die in the hospital for men were generally related to their medical condition, whereas the predictive factors for women were mainly related to functional dependency and social support. Social support had a trend towards predicting the place of death in women.

Effects of exercise rehabilitation on cardiovascular risk factors in older patients with peripheral arterial occlusive disease.

OBJECTIVE: The purpose of this study was to determine whether a 6-month exercise rehabilitation program can improve cardiovascular risk factors in patients with peripheral arterial occlusive disease (PAOD). METHODS: Thirty-four patients (mean age, 68 +/- 8 years; range 54-84 years) with PAOD with intermittent claudication (Fontaine stage II) and 14 longitudinal controls of comparable age with stage II PAOD enrolled in an exercise intervention at the University Medical Center and Veterans Affairs Medical Center at Baltimore, Maryland. The main outcome measures were lipid profile (total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol [LDL-C]), fasting glucose, blood pressure, body mass index, treadmill times to onset and maximal claudication pain, cardiopulmonary function (peak oxygen uptake), and ankle/brachial index. RESULTS: With exercise rehabilitation, treadmill times to onset and maximal claudication pain increased by 106% and 64% (P <.0001), whereas peak oxygen uptake increased 7% (P <.05). Exercise rehabilitation lowered total cholesterol and LDL-C levels by 5.2% (P <.005) and 8% (P <.01), respectively. Systolic blood pressure declined by 5.7% (P <.05) with no change in diastolic blood pressure. These changes in cholesterol and LDL-C concentrations were related to their initial values. All other cardiovascular risk factors measured did not change. There was no correlation between improvement of cardiovascular risk factors and functional performance measurements. None of the variables measured changed significantly in the control group. CONCLUSIONS: Exercise rehabilitation not only improves functional performance, but also results in favorable alterations in cardiovascular risk factor profile, which is an important element in the management of PAOD.