ABSTRACT
This study aimed the effect of n-acetylcysteine or ischemic preconditioning in hepatic and pulmonary damage after liver ischemia-reperfusion injury. Twenty-four male Wistar-EPM rats were assigned into four groups: (IR) Hepatic ischemia-reperfusion; (IPC) IPC achieved before hepatic ischemia; (NAC) Animals received NAC pretreatment; and Sham operated group. After 24 h of hepatic reperfusion, blood, liver, and pulmonary samples were evaluated. Nonparametric tests were used (P Subject(s)
Acetylcysteine/therapeutic use
, Free Radical Scavengers/therapeutic use
, Ischemic Preconditioning
, Liver/pathology
, Lung/pathology
, Reperfusion Injury/pathology
, Animals
, Aspartate Aminotransferases/blood
, Ischemic Preconditioning/methods
, Liver/blood supply
, Liver Circulation/physiology
, Lung/blood supply
, Male
, Random Allocation
, Rats
, Rats, Wistar
, Reperfusion Injury/prevention & control
, Time Factors
