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1.
Intern Med ; 62(8): 1167-1170, 2023 Apr 15.
Article in English | MEDLINE | ID: mdl-36047120

ABSTRACT

We herein report a 34-year-old man who presented with recurrent palpitations that occurred while swallowing solid food. Holter monitoring revealed atrial tachycardia (AT) while eating. In addition, chest computed tomography (CT) showed a small nodule in the front of the ascending aorta. Thoracoscopic surgery was performed to remove the nodule; a pathological examination revealed that the nodule was a thymic cyst. The AT disappeared postoperatively. This case demonstrates that a mediastinal nodule can cause swallowing-induced AT.


Subject(s)
Mediastinal Cyst , Tachycardia, Supraventricular , Male , Humans , Adult , Mediastinal Cyst/complications , Mediastinal Cyst/diagnostic imaging , Mediastinal Cyst/surgery , Deglutition , Mediastinum/pathology , Electrocardiography, Ambulatory
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4.
Intern Med ; 60(17): 2749-2755, 2021 Sep 01.
Article in English | MEDLINE | ID: mdl-33746167

ABSTRACT

Objective The aim of this study was to clarify the circadian and seasonal variations in addition to identify sex-based differences in Japanese patients with Takotsubo syndrome (TTS). Methods The authors conducted a retrospective observational study to analyse the differences between the groups based on sex. Patients The patients were registered out of each institute registry of the acute coronary syndrome (ACS) which contains a total of 10,622 cases in eight academic hospitals in east Japan. Results Data for 344 consecutive TTS (73 male and 271 female) were extracted from each hospital registry. In-hospital mortality was higher in the male group than in the female group (18% vs. 7%; p=0.005). With regard to the circadian variations in all study patients, TTS events occurred most often in the afternoon and least often during the night. Moreover, the patterns of circadian variations in the female and male groups were the same as that of all study patients. TTS events occurred most frequently in the autumn and least often in the spring in the whole study cohort. Moreover, the seasonal variation in the female group showed the same pattern as that of the whole cohort. However, there were no significant seasonal differences in the incidence of TTS in the male group. Conclusion In a multicenter study in Japan, seasonal variation was observed in the female group but not in the male group. Circadian variation was observed in both groups. These results suggested that the pathogenesis and clinical features of TTS might therefore differ according to sex.


Subject(s)
Takotsubo Cardiomyopathy , Female , Hospitals, University , Humans , Japan/epidemiology , Male , Registries , Seasons , Sex Factors , Takotsubo Cardiomyopathy/diagnosis , Takotsubo Cardiomyopathy/epidemiology
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