ABSTRACT
Morphometry is fundamental for studying and correlating neuronal morphology with brain functions. With increasing computational power, it is possible to extract morphometric characteristics automatically, including features such as length, volume, and number of neuron branches. However, to the best of our knowledge, there is no mapping of morphometric tools yet. In this context, we conducted a systematic search and review to identify and analyze tools within the scope of neuron analysis. Thus, the work followed a well-defined protocol and sought to answer the following research questions: What open-source tools are available for neuronal morphometric analysis? What morphometric characteristics are extracted by these tools? For this, aiming for greater robustness and coverage, the study was based on the paper analysis as well as the study of documentation and tests with the tools available in repositories. We analyzed 1,586 papers and mapped 23 tools, where NeuroM, L-Measure, and NeuroMorphoVis extract the most features. Furthermore, we contribute to the body of knowledge with the unprecedented presentation of 150 unique morphometric features whose terminologies were categorized and standardized. Overall, the study contributes to advancing the understanding of the complex mechanisms underlying the brain.
ABSTRACT
A Doença Pulmonar Obstrutiva Crônica (DPOC) ocasiona prejuízos na mecânica toraco-pulmonar. Estudos comprovam que a estimulação elétrica diafragmática é capaz de gerar benefícios ao portador de DPOC. Objetivo: Avaliar a influência da estimulação diafragmática elétrica transcutânea pela corrente russa na expansibilidade torácica em DPOC. Método: Estudo prospectivo e quase experimental com DPOC grau III e IV que estavam com estabilidade medicamentosa, cessação tabágica, e mantido o estilo de vida. Foram avaliados hábitos de vida, antropometria - IMC, escala de dispneia -Borg, frequência respiratória e cirtometria toraco-abdominal. Foi usada a corrente Endophasys R ET 9701 com tempo e frequência de 18 min. (20 a 30 Hz) e 12 min. (70 a 100 Hz), sendo de 1 a 6 seg de contração e o tempo de relaxamento duas vezes o tempo de contração, com a porcentagem da corrente de 20-50 por cento, totalizando 30 sessões (2x/semana). Os dados foram expressos por frequência absoluta e relativa e as comparações pelo teste Student (p<0,05). Resultados: 13 DPOC, 11 (84,6 por cento) homens, idade 68,46 ± 11,11 anos e IMC 25,13 ± 4,61 kg/m2, BORG: inicial 2,46±1,66 e final 2,23±1,30 e a FR: inicial 17 ± 5 ipm e final 16±4,3 ipm, diminuições na cirtometria (cm): axilar expiratória de 103±4,24 para 97,69±10,18; torácica de 98,25±2,47 para 96,38±9,97; torácica inspiratória de 99,25±3,88 para 98,73±9,93; umbilical expiratória de 99±2,82 para 93,54±13,83. Conclusão: A estimulação elétrica diafragmática por meio da corrente russa interfere na expansibilidade torácica e padrão respiratório de portadores de DPOC...
Chronic Obstructive Pulmonary Disease (COPD) causes injuries in the thoracic-pulmonary mechanics. Studies show that diaphragmatic electrical stimulation is able to generate benefits for patients with COPD. Objective: to evaluate the influence of transcutaneous electrical diaphragmatic stimulation by Russian current in chest expansion in COPD. Methods: a prospective quasi-experimental study with COPD, classification grade III and IV, drug stability, smoking cessation, and maintain of the lifestyle. The style of life, anthropometry - BMI, dyspnea - Borg scale, respiratory rate (RR) and thoracic-abdominal cirtometry were evaluated. The Endophasys R ET 9701 was used with time and attendance of the 18 min. (20 to 30 Hz) and 12 min. (70-100 Hz), with 1-6 sec of contraction and relaxation time (2x of contraction, with the percentage of the current 20-50 percent to 30 sessions (2x /week). Data were expressed descriptively as absolute and relative frequency, and comparisons were made by "t" test. Results: 13 COPD, 11(84.6 percent) males, age 68.46± 11.11 years, BMI 25.13 ±4.61 kg / m2, BORG: initial: 2.46 ± 1.66 and end: 2.23 ± 1.30 and the RR: initial: 17 ±5 bpm and end: 16 ± 4.3 ipm. There were changes in cirtometry (cm): axillary expiratory of 103 ± 4.24 to 97.69 ± 10,18; thoracic of 98.25 ± 2.47 to 96.38 ± 9.97; inspiratory thoracic of 99.25 ± 3.88 to 98.73 ± 9.93; expiratory umbilical 99 ± 2.82 to 93.54 ± 13.83. Conclusion: diaphragmatic electrical stimulation through the Russian current promotes benefits in the components of respiratory mechanics as chest expansion and breathing pattern in patients with COPD...
Subject(s)
Humans , Male , Female , Middle Aged , Pulmonary Disease, Chronic Obstructive/rehabilitation , Transcutaneous Electric Nerve Stimulation , Prospective Studies , Physical Therapy Modalities , Electric Stimulation Therapy/methodsABSTRACT
Pulmonary artery sarcomas (PAS) are rare and probably incurable tumours. The clinical manifestations are non-specific and very similar to that of patients with thromboembolic disease, resulting in delay of the correct diagnosis and proper treatment. We report the case of a 66-year-old woman with PAS diagnosed by computed tomography guided biopsy. Chemotherapy treatment was initiated but the patient died 11 months after diagnosis.
