1.
Org Lett
; 11(18): 4116-9, 2009 Sep 17.
Article
in English
| MEDLINE
| ID: mdl-19673513
ABSTRACT
The intramolecular Rauhut-Currier reaction creates a carbon-carbon bond between two tethered Michael acceptors. Previous asymmetric versions have relied on 1,4-additions of chiral nucleophilic catalysts. Herein, we investigate a novel strategy that involves the formation of electron rich dienamines as key intermediates. Our methodology provides an efficient entry to the iridoid framework.