Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 40
Filter
1.
Acta Anaesthesiol Scand ; 57(5): 660-8, 2013 May.
Article in English | MEDLINE | ID: mdl-23289798

ABSTRACT

INTRODUCTION: This study aims to compare the trauma system before and after implementing a physician-staffed helicopter emergency medical service (PS-HEMS). Our hypothesis was that PS-HEMS would reduce time from injury to definitive care for severely injured patients. METHODS: This was a prospective, controlled, observational study, involving seven local hospitals and one level I trauma centre using a before and after design. All patients treated by a trauma team within a 5-month period (1 December 2009-30 April 2010) prior to and a 12-month period (1 May 2010-30 April 2011) after implementing a PS-HEMS were included. We compared time from dispatch of the first ground ambulance to arrival in the trauma centre for patients with Injury Severity Score (ISS) > 15. Secondary end points were the proportion of secondary transfers and 30-day mortality. RESULTS: We included 1788 patients, of which 204 had an ISS > 15. The PS-HEMS transported 44 severely injured directly to the trauma centre resulting in a reduction of secondary transfers from 50% before to 34% after implementation (P = 0.04). Median delay for definitive care for severely injured patients was 218 min before and 90 min after implementation (P < 0.01). The 30-day mortality was reduced from 29% (16/56) before to 14% (21/147) after PS-HEMS (P = 0.02). Logistic regression showed PS-HEMS had an odds ratio (OR) for survival of 6.9 compared with ground transport. CONCLUSIONS: Implementation of a PS-HEMS was associated with significant reduction in time to the trauma centre for severely injured patients. We also observed significantly reduced proportions of secondary transfers and 30-day mortality.


Subject(s)
Air Ambulances/statistics & numerical data , Emergency Medical Services/methods , Physicians , Wounds and Injuries/therapy , Adolescent , Adult , Aged , Aged, 80 and over , Denmark , Female , Humans , Injury Severity Score , Male , Middle Aged , Prospective Studies , Time Factors , Young Adult
2.
Vox Sang ; 100(2): 239-46, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21118266

ABSTRACT

BACKGROUND AND OBJECTIVES: Transfusion of autologous whole blood is one available method to reduce the need for allogenic blood transfusion. The objective of this study was to investigate the safety of transfusion of intra-operative autologous whole blood by monitoring plasma concentration of laboratory variables and adverse events after transfusion with the Sangvia(®) system. MATERIALS AND METHODS: The clinical trial was designed as an open, prospective, multi-centre study, and a total of 20 patients undergoing primary hip arthroplasty were included. Systemic blood samples were taken and analysed preoperatively, at transfusion start and end and at 3, 6, 24 and 48 h after the transfusion. RESULTS: Elevated values of complement activation and pro-inflammatory cytokines were seen in the intra-operatively collected blood but the impact on systemic levels were limited with low peak levels, systemic elevations before transfusion and normalization during the study period. Elevated levels of free haemoglobin and potassium were also detected in the intra-operatively collected blood, but systemic values were within reference values after the transfusion. No clinically relevant adverse event occurred during the study. CONCLUSION: Inflammatory mediators and plasma haemoglobin were increased in intra-operatively salvaged and filtered blood compared to circulatory levels. Intra-operative retransfusion of autologous whole blood caused a transient systemic increase that normalized in the early postoperative period. There were no significant adverse events reported in the study. These data suggest that the Sangvia(®) system can be used for intra-operative collection and retransfusion of salvaged blood.


Subject(s)
Blood Transfusion, Autologous/instrumentation , Complement Activation , Interleukins/blood , Intraoperative Care/instrumentation , Operative Blood Salvage/instrumentation , Aged , Arthroplasty, Replacement, Hip/methods , Blood Transfusion, Autologous/adverse effects , Blood Transfusion, Autologous/methods , Female , Humans , Intraoperative Care/methods , Male , Monitoring, Physiologic/instrumentation , Monitoring, Physiologic/methods , Operative Blood Salvage/adverse effects , Operative Blood Salvage/methods
3.
Vox Sang ; 95(1): 33-8, 2008 Jul.
Article in English | MEDLINE | ID: mdl-18444947

ABSTRACT

BACKGROUND AND OBJECTIVES: The aim of the present study was to investigate the quality of shed blood collected in a new intraoperative autotransfusion system (Sangvia, AstraTech, Sweden) and to study whether heparin-coated surfaces in the device reduce the production of inflammatory mediators. MATERIAL AND METHODS: The study was randomized and prospective. Twelve total hip arthroplasty patients whose blood was collected with a device having a heparin-coated surface and 12 patients whose blood was collected with a device having a non-heparin-coated surface were included. Venous blood was drawn from the patients preoperatively. Intraoperatively 200 ml salvaged blood was collected and samples were also withdrawn; samples were obtained from the blood bag. RESULTS: Compared to venous blood, elevated concentrations of interleukin 6 (IL-6), IL-8, C3a and polymorphonuclear elastase were found in collected blood. No significant differences in inflammatory mediators were found between the heparin-coated and the non-heparin-coated groups. The median haemoglobin concentration in the salvaged blood was 74 g/l in both groups. Plasma haemoglobin and potassium concentrations were also elevated. There were no significant differences between the groups. CONCLUSION: The present study indicates that the blood salvaged intraoperatively contains elevated levels of complement split product and proinflammatory cytokines and that heparin-coated surfaces of the salvage device do not significantly influence the formation of inflammatory mediators.


Subject(s)
Arthroplasty, Replacement, Hip/methods , Blood Transfusion, Autologous/instrumentation , Coated Materials, Biocompatible/chemistry , Heparin , Intraoperative Care/methods , Blood Loss, Surgical , Blood Transfusion, Autologous/standards , Complement C3a/analysis , Cytokines/blood , Humans
4.
Int J Radiat Oncol Biol Phys ; 48(2): 555-63, 2000 Sep 01.
Article in English | MEDLINE | ID: mdl-10974476

ABSTRACT

PURPOSE: To analyze the effect of irradiation on cancellous bone healing at different times after irradiation and to study if hyperbaric oxygen therapy (HBO) would affect the bone healing capacity, when delivered directly after irradiation. METHODS AND MATERIALS: Rabbits were given a single dose of 15 Gy (60)Co radiation to one hind leg, the other hind leg serving as control. A standardized defect through the femoral metaphysis of the rabbits was created by a trephine drill biopsy at different times after irradiation. New bone formation in the defect was evaluated by a new biopsy through the previous defect after a healing time of 8 weeks. The mineral contents of the biopsies were analyzed by microradiography and microdensitometry. RESULTS: There was a large variation in the bone-forming capacity expressed as bone mineral content between the animals. No statistically significant differences could be detected regarding the effect of irradiation, HBO, or delayed surgery. Qualitative histology revealed more pronounced inflammation, fibrosis, and bone resorption in the irradiated bone. CONCLUSIONS: No definite conclusions can be drawn from the results of this study, however it might be hypothesized that cancellous bone recovers faster than cortical bone from radiation trauma.


Subject(s)
Bone Development/radiation effects , Bone and Bones/radiation effects , Hyperbaric Oxygenation , Radiation Injuries/physiopathology , Animals , Bone Development/physiology , Bone and Bones/diagnostic imaging , Bone and Bones/physiology , Female , Femur/physiology , Femur/radiation effects , Hindlimb/radiation effects , Male , Microradiography , Rabbits , Radiation Injuries/diagnostic imaging , Radiobiology , Tibia/physiology , Tibia/radiation effects , Time Factors
5.
Clin Implant Dent Relat Res ; 2(1): 42-9, 2000.
Article in English | MEDLINE | ID: mdl-11359274

ABSTRACT

BACKGROUND: The time interval from irradiation to implant surgery has been considered an impact factor for implant integration in irradiated bone and the importance of a long interval between the radiation trauma and reconstructive bone surgery has been suggested. PURPOSE: The present study was undertaken to histomorphometrically and biomechanically analyze the effect of delayed implant placement on bone healing around titanium implants in irradiated bone. MATERIALS AND METHODS: Rabbits were given a single dose of 15 Gy Cobalt60 radiation to one hind leg, the other hind leg serving as a control. Titanium screws were inserted into the femur and tibia directly and at 12 weeks and 52 weeks after irradiation. The implants were evaluated after a healing time of 8 weeks. The torques necessary for removal of the implants were measured. Histomorphometry with respect to bone-metal contact and amount of bone surrounding the implants was performed. RESULTS: The biomechanical force necessary to unscrew the titanium implants in the irradiated bone was significantly increased after a resting period of 1 year between irradiation and implant placement, compared to direct implant placement. The histomorphometric evaluation showed an improvement of bone healing around the implants in the irradiated bone, both after a resting period of 12 weeks and after 1 year compared to direct implant placement. CONCLUSIONS: It is concluded that a relatively long interval between irradiation and reconstructive bone surgery will improve osseointegration of titanium implants in irradiated rabbit bone.


Subject(s)
Bone and Bones/radiation effects , Dental Implants , Titanium , Animals , Biomechanical Phenomena , Bone and Bones/pathology , Bone and Bones/physiopathology , Bone and Bones/surgery , Cobalt Radioisotopes , Femur/pathology , Femur/physiopathology , Femur/radiation effects , Femur/surgery , Follow-Up Studies , Osseointegration , Rabbits , Radiopharmaceuticals , Statistics as Topic , Statistics, Nonparametric , Stress, Mechanical , Surface Properties , Tibia/pathology , Tibia/physiopathology , Tibia/radiation effects , Tibia/surgery , Time Factors , Torque , Wound Healing
6.
Int J Oral Maxillofac Implants ; 14(5): 699-706, 1999.
Article in English | MEDLINE | ID: mdl-10531742

ABSTRACT

The present study was undertaken to histomorphometrically analyze early peri-implant bone tissue reactions that occur after radiotherapy and to determine whether hyperbaric oxygen therapy (HBO) affects bone tissue at the microscopic level by altering bone morphology. Twelve rabbits received a single dose (15 Gy) of cobalt60 radiation to one hind leg and the other hind leg served as a control. Titanium screws were placed into the femur and tibia directly after irradiation. Six animals received HBO during the first 4 postoperative weeks. After 8 weeks of follow-up, bone specimens containing the screws were prepared for histomorphometry. Bone-metal contact and the amount of bone in the thread areas and in the mirror areas were measured in a blinded manner. Periosteal bone formation and bone remodeling decreased after irradiation; also after HBO treatment. Hyperbaric oxygen therapy improved bone formation in nonirradiated bone and to some extent also in the irradiated bone. Bone maturation was improved in the HBO animals after irradiation. It was concluded that irradiation reduces the capacity for osseointegration of titanium implants. Hyperbaric oxygen treatment may improve bone formation and especially has positive effects on bone maturation after irradiation.


Subject(s)
Bone Screws , Bone and Bones/radiation effects , Hyperbaric Oxygenation , Titanium , Animals , Bone Remodeling/radiation effects , Bone and Bones/pathology , Cobalt Radioisotopes/administration & dosage , Female , Femur/pathology , Femur/radiation effects , Follow-Up Studies , Male , Osseointegration/radiation effects , Osteogenesis/radiation effects , Rabbits , Radiation Dosage , Radiopharmaceuticals/administration & dosage , Single-Blind Method , Surface Properties , Tibia/pathology , Tibia/radiation effects , Titanium/chemistry
7.
Clin Orthop Relat Res ; (352): 81-94, 1998 Jul.
Article in English | MEDLINE | ID: mdl-9678036

ABSTRACT

The culmination of more than 10 years of laboratory and clinical research has been the clinical trial of a novel hip arthroplasty for osseointegration. The femoral component of this Gothenburg hip is a neck retaining, threaded fixture with rotational symmetry, produced in commercially pure titanium with a specific surface texture. Proximally, a standard orthopaedic taper trunnion mates with a 28-mm diameter zirconia head that articulates against the acetabular component. The latter is also of textured commercially pure titanium, encapsulating a thick ultra high molecular weight polyethylene liner. Dedicated alignment guides and cutting instruments ensure accurate bone preparation and implant placement. Limited clinical trials commenced in 1992 and expanded to multicenter clinical trials in 1997. Every hip has been monitored with radiostereometry to measure migration to an accuracy of 0.1 mm. All calcar implanted femoral components show excellent function at 4 to 5 years followup, with no migration revealed by radiostereometry.


Subject(s)
Arthroplasty, Replacement, Hip , Hip Prosthesis , Osseointegration , Animals , Follow-Up Studies , Humans , Prosthesis Design , Time Factors , Titanium
8.
Article in English | MEDLINE | ID: mdl-8270310

ABSTRACT

This study investigated the influence of a single 15-Gy dose of irradiation on the capacity of titanium screws to integrate in irradiated bone tissue. The biomechanical force necessary to unscrew the titanium implants 8 weeks after placement was 54% lower for implants in irradiated bone tissue compared to implants in nonirradiated bone tissue. Postirradiation use of hyperbaric oxygen treatment at 2.8 ATA (2-hour daily treatments for 21 days) increased the biomechanical force necessary to unscrew the titanium implants by 44% in irradiated bone and by 22% in nonirradiated bone.


Subject(s)
Bone Regeneration/radiation effects , Bone and Bones/radiation effects , Hyperbaric Oxygenation , Osseointegration/radiation effects , Prostheses and Implants , Animals , Biomechanical Phenomena , Bone Remodeling/radiation effects , Bone and Bones/metabolism , Dose-Response Relationship, Radiation , Female , Male , Phosphates/metabolism , Rabbits , Radiation-Protective Agents , Titanium
9.
Clin Otolaryngol Allied Sci ; 17(6): 482-6, 1992 Dec.
Article in English | MEDLINE | ID: mdl-1493620

ABSTRACT

The purpose of this evaluation is to compare whether retention of auricular prostheses, through utilization of osseointegrated implants rather than by adhesive, provides any improvement in patient acceptance and prosthesis longevity. Forty-seven out of a total of 49 patients having facial prostheses, retained by means of Brånemark fixtures, were surveyed. Ease of retention was noted in 91% of the patients. Satisfaction with the shape of the prosthesis, colour and ease of positioning was 100, 85 and 98% respectively. None of the patients experienced skin irritation under the prosthesis and 94% of them wore their prosthesis daily. Of the 13 patients with previous prosthesis experience, 92% stated improved retention and all of them found ease of positioning and wearing comfort had improved. Durability was better in 62%, unchanged in 23% and worse in 15% of these 13 patients.


Subject(s)
Ear, External , Prostheses and Implants , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Osseointegration , Patient Satisfaction
10.
Int J Pediatr Otorhinolaryngol ; 24(3): 235-43, 1992 Nov.
Article in English | MEDLINE | ID: mdl-1399312

ABSTRACT

The aim of this study is to present our clinical experience with tissue-integrated extra-oral implants in children. Thirty consecutive cases of children with a total of 59 standard titanium fixtures inserted in the temporal bones and used as bone-anchorage for auricular epistheses (14 cases) and hearing aids (16 cases) were studied. The surgical procedure is performed in two steps and involves an extremely gentle handling of the soft tissue and bone. The patients were followed with regular check-ups for an average of 40 months after hearing aid/prosthesis fitting. The fixture survival rate was 96.6% for the whole group. The hearing aids had a reaction-free skin penetration in 91.67% of the postoperative observations and the prostheses had a reaction-free skin penetration in 75.00% of the postoperative observations. It is concluded that the use of 'osseointegrated', implants in carefully selected cases, in children, appears to be a reliable method for bone anchorage of epistheses and bone conduction hearing aids. A close follow-up and control of this patient category is especially important with respect to the long-term results.


Subject(s)
Ear/abnormalities , Osseointegration , Prostheses and Implants , Temporal Bone , Adolescent , Child , Child, Preschool , Ear, External/abnormalities , Hearing Aids , Humans
11.
Article in English | MEDLINE | ID: mdl-1299649

ABSTRACT

This investigation was conducted to evaluate osseointegrated skin-penetrating facial titanium implants used for anchoring facial prostheses over a 5-year period and to recommend guidelines for the use of osseointegrated implants in the restorative treatment of auricular and orbital defects. The total success rate for implant survival was 95.6% in the auricular defects and 67.2% in the orbital defects. Approximately 10% of the patients will have some skin problems, whereas the remaining 90% will have no or minimal problems. The possibility of achieving osseointegration around an orbital defect is not as good as in the mastoid process. Success criteria for the use of implants in the craniofacial region are given.


Subject(s)
Ear, External , Maxillofacial Prosthesis , Orbit , Prostheses and Implants , Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Follow-Up Studies , Humans , Male , Mastoid/surgery , Middle Aged , Osseointegration , Prostheses and Implants/adverse effects , Prosthesis Failure , Retrospective Studies , Skin Diseases/etiology , Titanium , Treatment Outcome
12.
Article in English | MEDLINE | ID: mdl-1398819

ABSTRACT

Since the introduction of osseointegrated titanium implants for bone-anchored facial and dental prostheses, an increasing number of irradiated patients are being treated with this technique. Although the number of patients who have had titanium implants after irradiation is limited, available statistics point to a tendency of a higher implant loss frequency as compared with nonirradiated patients. This review discusses factors behind deleterious tissue effects and implant failures from irradiation and points to possibilities to improve the surgical outcome with special reference to hyperbaric oxygen therapy.


Subject(s)
Bone and Bones/radiation effects , Dental Implants , Hyperbaric Oxygenation , Jaw/radiation effects , Osseointegration/radiation effects , Radiotherapy/adverse effects , Animals , Facial Bones/radiation effects , Humans , Titanium
13.
Article in English | MEDLINE | ID: mdl-1820313

ABSTRACT

Insertion torque and removal torque of fixtures were measured using human cadaver temporal bone and human living bone. The torque level for fracturing the threads of the bone was also measured. The maximum insertion torque exerted without causing a break in bone threads was 70.0 Ncm in bicortical bone and 50.0 Ncm in unicortical bone. The relationship between insertion torque and removal torque indicated a positive correlation between both sites. However, removal torque was lower than insertion torque in all measurements. The fracture points of bone threads were 77.0 Ncm in bicortical bone and 57.7 Ncm in unicortical bone by mean. Microfractures were observed mainly in the thread bases and were directed upward in the histologic specimens examined.


Subject(s)
Osseointegration , Prostheses and Implants , Aged , Bone and Bones , Fractures, Bone/etiology , Fractures, Bone/physiopathology , Humans , Male , Mastoid , Middle Aged , Prostheses and Implants/adverse effects , Rotation , Stress, Mechanical , Temporal Bone , Titanium
14.
Ann Otol Rhinol Laryngol Suppl ; 151: 1-16, 1990 Oct.
Article in English | MEDLINE | ID: mdl-2121086

ABSTRACT

In 1977, a new phase began in hearing rehabilitation of patients with chronic middle and external diseases and atresias. Thus far, these patients have had to rely on conventional bone conduction and air conduction devices that for various reasons give poor rehabilitation. The principle of the new treatment, made possible by the Swedish bone-anchored hearing system, is simple: sound vibrations are directly transmitted to the skull bone via a skin-penetrating titanium implant and then are further transmitted to the cochlea, bypassing the middle ear. The present paper summarizes our results in 147 patients over 10 years, including a total of 6,334 follow-up months. No significant rate of skin infections was observed. In over 93% of the observations, no sign of adverse skin reaction was seen. When herein-suggested indications for treatment with the bone-anchored sound processor HC-200 are followed, the success rate is over 90%. The improved quality of life reported by the patients is a combination of improved quality of sound, improved comfort, and relief from middle ear and ear canal disease occasioned by conventional hearing aids.


Subject(s)
Hearing Aids , Mastoid/surgery , Prostheses and Implants , Adolescent , Adult , Aged , Audiometry , Auditory Threshold , Bone Conduction , Child , Child, Preschool , Female , Hearing Disorders/physiopathology , Hearing Disorders/surgery , Humans , Male , Methods , Middle Aged , Postoperative Complications , Titanium
15.
Acta Paediatr Scand ; 79(1): 118-20, 1990 Jan.
Article in English | MEDLINE | ID: mdl-2316354

ABSTRACT

Two cases of facial palsy in connection with acute otitis media are presented. The patients were 2 months and 2 years old, respectively. In both cases the facial palsy disappeared after treatment with myringotomy and antibiotics. The etiological mechanisms behind and the different approaches to the treatment of facial palsy in children with acute otitis media are discussed.


Subject(s)
Facial Paralysis/etiology , Otitis Media/complications , Acute Disease , Child, Preschool , Female , Humans , Infant
16.
Acta Otolaryngol ; 109(1-2): 130-6, 1990.
Article in English | MEDLINE | ID: mdl-2309552

ABSTRACT

Spontaneous and experimentally induced cholesteatoma in the Mongolian gerbil has been found to exhibit histopathological similarities to human aural cholesteatoma and has been suggested as an experimental model for studies of the clinical situation. In an attempt to further characterize this model, we compared experimentally induced cholesteatomas in the external auditory canal from gerbils with those of the human ear by means of a correlated histopathologic and enzyme histochemical study. The human and gerbilline cholesteatomas revealed similar histopathologic features. Even enzyme histochemically, the human and experimentally induced cholesteatomas demonstrated similar features. Thus glucose-6-phosphate dehydrogenase activity, an indicator of oxidative metabolism, was demonstrated especially in the stratum granulosum cells of the heavily orthokeratinizing squamous epithelium adjacent to the cholesteatomas. The human ear canal skin also revealed enzyme histochemical characteristics similar to the squamous epithelium lining the human cholesteatoma. The hydrolytic enzyme activity (leucyl-aminopeptidase) was strong in the connective tissue surrounding human cholesteatoma when compared with that of ear canal skin. In the gerbilline cholesteatoma, this activity was demonstrated especially in the connective tissue adjacent to eroded bone, which possibly may facilitate cholesteatoma progression. We conclude that experimentally induced cholesteatoma has both histophatological and enzyme histochemical similarities to human aural cholesteatoma and therefore it is suggested that the gerbilline model may be used for studies on the development of human cholesteatoma. Our results support the view that cholesteatoma may originate from migrated hyperkeratinizing cells from the epidermis of the tympanic membrane or the meatus.


Subject(s)
Cholesteatoma/enzymology , Ear Diseases/enzymology , Acid Phosphatase/metabolism , Adolescent , Adult , Aged , Aminopeptidases/metabolism , Animals , Cholesteatoma/pathology , Disease Models, Animal , Ear Canal/enzymology , Ear Canal/pathology , Ear Diseases/pathology , Ear, Middle/enzymology , Ear, Middle/pathology , Epithelium/enzymology , Female , Gerbillinae , Glucosephosphate Dehydrogenase/metabolism , Histocytochemistry , Humans , Male , Middle Aged
17.
Int J Oral Maxillofac Implants ; 5(3): 233-46, 1990.
Article in English | MEDLINE | ID: mdl-2098327

ABSTRACT

A surgical technique for rehabilitation of severely resorbed edentulous maxillae using fixed prostheses or overdentures supported by osseointegrated fixtures in immediate autogenous corticocancellous bone grafts from the ilium is described. The results of the first 23 consecutively treated patients are reviewed. The mean observation time was 4.2 years (range 1 to 10 years). A total of 124 fixtures was originally placed into the grafts, supplemented with 16 fixtures inserted later into seven of the jaws. Throughout their observation period, 17 of the patients had continuously stable prostheses. The remaining five had overdentures, and one patient had resorted to a conventional complete denture. After 4 years, 12 of 16 patients had continuously stable prostheses. Corresponding values at 5 years were 7 of 8 patients. Calculated from the date of abutment connection, 82.1% and 81.6% of the original fixtures were clinically stable and radiographically osseointegrated after 4 and 5 years in function, respectively. From the date of fixture placement, the corresponding figures were 75.3% and 73.8%, respectively. The mean marginal bone loss after the first year of prosthesis function was 1.49 mm. The annual marginal bone loss thereafter was about 0.1 mm. The results indicate that this technique is worthwhile for patients with extreme maxillary atrophy and who cannot wear conventional complete dentures.


Subject(s)
Alveolar Bone Loss/rehabilitation , Alveolar Ridge Augmentation/methods , Bone Transplantation , Dental Implantation, Endosseous , Adult , Denture, Overlay , Female , Humans , Jaw, Edentulous/rehabilitation , Male , Middle Aged , Osseointegration , Prognosis
18.
J Laryngol Otol ; 103(12): 1202-5, 1989 Dec.
Article in English | MEDLINE | ID: mdl-2614241

ABSTRACT

A case is presented of a 3-year-old girl with no previous history of ear disease or developmental defects who bled profusely upon (right) myringotomy. The haemorrhage could only be stopped with the aid of an ear insert and a nasopharyngeal balloon catheter. The balloon catheter was removed the following day but the girl had to use an ear insert for a total of 76 days following myringotomy because of repeated haemorrhage from the ear. The subsequent investigation using CT and angiography revealed an aberrant internal carotid artery in the middle ear. It is concluded that the one most important factor in the handling of these cases is to be aware of the existence of aberrant internal carotid arteries and to have a high degree of suspicion when encountering any abnormal clinical or radiological findings which might point in the direction of vascular abnormalities. The failure to detect this condition before any surgical intervention on the affected ear can have disastrous consequences. The method of choice in handling these cases is one of avoidance of middle ear manipulation in order not to cause haemorrhage from the aberrant artery.


Subject(s)
Carotid Artery, Internal/abnormalities , Hemorrhage/etiology , Tympanic Membrane/surgery , Carotid Artery, Internal/diagnostic imaging , Child, Preschool , Ear, Middle/diagnostic imaging , Female , Humans , Intraoperative Complications , Radiography
19.
Arch Otolaryngol Head Neck Surg ; 115(2): 238-9, 1989 Feb.
Article in English | MEDLINE | ID: mdl-2536546

ABSTRACT

In September 1979 the patient, a man born in 1964, noticed pain and swelling of the right cheek in combination with periods of epistaxis. A computed tomographic scan revealed a tumor extending from the middle of the right nasal cavity into the right maxillary antrum and up toward the orbital floor with destruction of the medial and lateral walls of the antrum and continuing into the sphenoid sinus on the right side and dorsal to the pterygoid process up under the base of the skull. Angiography showed arterial supply mainly from the right external carotid artery, but also from the right internal carotid artery and the left external carotid artery. The process was diagnosed as a juvenile nasopharyngeal angiofibroma. In spite of two attempts at resection of the tumor and arterial embolization, the tumor progressed intracranially. Further operative attempts were decided against, and the patient was followed with repeated computed tomographic scans. The tumor eventually became involuted; eight years after the initial diagnosis, there was no evidence of computed tomographic scans of intracranial growth of the tumor.


Subject(s)
Histiocytoma, Benign Fibrous/diagnostic imaging , Nasopharyngeal Neoplasms/diagnostic imaging , Adult , Embolization, Therapeutic , Histiocytoma, Benign Fibrous/blood supply , Histiocytoma, Benign Fibrous/surgery , Humans , Ligation , Male , Nasopharyngeal Neoplasms/blood supply , Nasopharyngeal Neoplasms/surgery , Neoplasm Invasiveness , Neoplasm Regression, Spontaneous , Tomography, X-Ray Computed
20.
Article in English | MEDLINE | ID: mdl-2689335

ABSTRACT

The vital microscopic chamber is an experimental implant of commercially pure titanium that admits in vivo and in situ observations of bone vascularity and bone remodeling. The bone growth chamber and the bone harvest chamber, in particular, are useful tools for quantifying bone regeneration under the most variable experimental conditions.


Subject(s)
Bone Regeneration , Dental Implantation/instrumentation , Diffusion Chambers, Culture , Animals , Dental Implants
SELECTION OF CITATIONS
SEARCH DETAIL
...