ABSTRACT
Sertoliform endometrioid carcinoma of the ovary (SEC) is an uncommon variant that bears histologic similarity to sertoli and sertoli-leydig cell tumors. We report an interesting case of SEC in a 55-year-old female with a left ovarian mass with torsion. Histology revealed an SEC, featuring foci of typical endometrioid carcinoma, and areas composed of uniform, small, hollow tubules lined by columnar cells with apical cytoplasm. Tumor cells were strongly immunoreactive for EMA and cytokeratin but negative for inhibin; thus, confirming the diagnosis of SEC ovary. Recognition of this tumor is important as it is a well-differentiated, low-grade malignancy that displays good prognosis when confined to the ovary.
ABSTRACT
Malakoplakia of the gastrointestinal tract is a rare chronic inflammatory disorder, usually affecting the descending colon, sigmoid colon and rectum. It is commonly seen in adults. Only few cases have been reported in children. We report a case of malakoplakia of colon and rectum in a 7-year-old child who presented with multiple polyposis coli.
Subject(s)
Adenomatous Polyposis Coli/diagnosis , Adenomatous Polyposis Coli/pathology , Colon/pathology , Colonic Diseases/diagnosis , Colonic Diseases/pathology , Malacoplakia/diagnosis , Malacoplakia/pathology , Adenomatous Polyposis Coli/surgery , Child , Colon/surgery , Colonic Diseases/surgery , Diagnosis, Differential , Histocytochemistry , Humans , Malacoplakia/surgery , Male , Microscopy , Radiography, AbdominalABSTRACT
Renal angiomyolipoma is a distinctive benign neoplasm that occurs either sporadically or in patients with tuberous sclerosis complex. A 45-year-old woman was admitted with history offlank pain and vomiting. There were no signs suggestive of tuberous sclerosis either in the patient or her family. At operation, she had a left renal mass with nephrolithiasis and hydronephrosis. Histopathology revealed epithelioid angiomyolipoma of the left kidney with chronic pyelonephritis. Immunohistochemistry confirmed the diagnosis of angiomyolipoma. This case is presented to highlight the epithelioid variant of angiomyolipoma which may behave in an aggressive manner.
Subject(s)
Angiomyolipoma/pathology , Kidney Neoplasms/pathology , Angiomyolipoma/diagnosis , Angiomyolipoma/metabolism , Antigens, Neoplasm , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Kidney Neoplasms/diagnosis , Kidney Neoplasms/metabolism , Melanoma-Specific Antigens , Middle Aged , Neoplasm Proteins/metabolismABSTRACT
Gonadoblastomas are rare germ cell and sex cord stromal tumours, often associated with dysgerminomas. They occur almost entirely in patients with pure or mixed gonadal dysgenesis and in male pseudohermaphroditism. A 19 year old female was admitted in our hospital for evaluation of primary amenorrhoea. She had poor secondary sexual characters, left sided streak gonad and right sided ovarian tumour. Histopathology showed gonadoblastoma in streak gonad with contralateral dysgerminoma. This case is presented because of its rarity and clinical importance of recognizing such cases because of excellent prognosis.
