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4.
C R Seances Soc Biol Fil ; 170(2): 477-81, 1976.
Article in French | MEDLINE | ID: mdl-134821

ABSTRACT

Some ascite tumours have been induced in rat by intraperitoneal injection of RadLV and in mouse by intraperitoneal injection of RadLV, or of protozoa such as Trypanosoma brucei and Toxoplasma gondii. Cytological examination of the resulting ascite tumours has shown that chromosome aberrations were associated with the presence of C and A viral particles.


Subject(s)
Chromosome Aberrations , Peritoneal Neoplasms/pathology , Animals , Ascites/pathology , Mice , Neoplasms, Experimental , Rats , Retroviridae/pathogenicity , Toxoplasma/pathogenicity , Trypanosoma brucei brucei/pathogenicity
5.
Cell Tissue Res ; 157(1): 93-9, 1975.
Article in English | MEDLINE | ID: mdl-1122535

ABSTRACT

A quantitative method for the evaluation of the importance of pinocytotic phenomena in cerebral cortex capillaries is proposed. The method involved the counting of labeled "caveolae intracellulares" in endothelia cells with the use of horseradish peroxidase as a tracer molecule. A mean pinocytotic value per capillary is then computed. It is demonstrated that the value obtained after irradiation of the brain is higher than in control animals. This information may provide an ultrastructural quantitative approach to the analysis of the blood brain barrier and of other problems related to vascular permeability of the cerebral cortex.


Subject(s)
Blood-Brain Barrier , Capillary Permeability , Cerebral Cortex/enzymology , Peroxidases/metabolism , Animals , Blood-Brain Barrier/radiation effects , Capillary Permeability/radiation effects , Endothelium/enzymology , Epithelial Cells , Epithelium/enzymology , Female , Pinocytosis/radiation effects , Radiation Effects , Rats
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