Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 10 de 10
Filter
Add more filters










Publication year range
1.
Burns ; 2024 Apr 17.
Article in English | MEDLINE | ID: mdl-38902131

ABSTRACT

BACKGROUND: Value-based healthcare (VBHC) is increasingly implemented in healthcare worldwide. Transparent measurement of the outcomes most important and relevant to patients is essential in VBHC, which is supported by a core set of most important quality indicators and outcomes. Therefore, the aim of this study was to develop a VBHC-burns core set for adult burn patients. METHODS: A three-round modified national Delphi study, including 44 outcomes and 24 quality indicators, was conducted to reach consensus among Dutch patients, burn care professionals and researchers. Items were rated on a nine-point Likert scale and selected if ≥ 70% in each group considered an item 'important'. Subsequently, instruments quantifying selected outcomes were identified based on a literature review and were chosen in a consensus meeting using recommendations from the Dutch consensus-based standard set and the Dutch Centre of Expertise on Health Disparities. Time assessment points were chosen to reflect the burn care and patient recovery process. Finally, the initial core set was evaluated in practice, leading to the adapted VBHC-burns core set. RESULTS: Twenty-seven patients, 63 burn care professionals and 23 researchers participated. Ten outcomes and four quality indicators were selected in the Delphi study, including the outcomes pain, wound healing, physical activity, self-care, independence, return to work, depression, itching, scar flexibility and return to school. Quality indicators included shared decision-making (SDM), the number of patients receiving aftercare, determination of burn depth, and assessment of active range of motion. After evaluation of its use in clinical practice, the core set included all items except SDM, which are assessed by 9 patient-reported outcome instruments or measured in clinical care. Assessment time points included are at discharge, 2 weeks, 3 months, 12 months after discharge and annually afterwards. CONCLUSION: A VBHC-burns core set was developed, consisting of outcomes and quality indicators that are important to burn patients and burn care professionals. The VBHC-burns core set is now systemically monitored and analysed in Dutch burn care to improve care and patient relevant outcomes. As improving burn care and patient relevant outcomes is important worldwide, the developed VBHC-burns core set could be inspiring for other countries.

2.
Burns ; 43(4): 733-740, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28040360

ABSTRACT

AIM: The aim of this study was to compare the clinical outcomes of different treatment strategies for children with partial-thickness scalds at two burn centers. At the first burn center, these burns were treated with a hydrofiber dressing (Aquacel®, Convatec, Inc.®, Princeton, NJ, USA) or silver sulfadiazine (SSD, Flammazine®, Sinclair IS Pharma, London, UK Pharmaceuticals), while at the second burn center, cerium nitrate-silver sulfadiazine (CN-SSD, Flammacerium®, Sinclair IS Pharma, London, UK Pharmaceuticals) was used. METHODS: A two-center retrospective study was conducted of children admitted between January 2009 and December 2013 for partial-thickness scalds up to 10% TBSA who were treated primarily with a hydrofiber dressing or silver sulfadiazine (Burn Center Rotterdam) vs. cerium nitrate-silver sulfadiazine (Burn Center Groningen). The Dutch Burn Repository R3 and the electronic medical records of the study population were used for data extraction. The primary outcome was the time to wound healing. The secondary outcomes were the length of hospital stay, wound infection, and surgical treatment. RESULTS: The time to wound healing differed between the groups (HR=1.46, 95%CI 1.17-1.82); the shortest time to wound healing was observed in the patients treated with CN-SSD (median 13 days), compared with 15 days for the patients treated with hydrofiber and 16 days for the patients treated with SSD (p<0.01). The length of stay was significantly shorter for the hydrofiber patients (medians: hydrofiber 3 days, SSD 10 days and CN-SSD 7 days; p<0.01), but their outpatient treatment period was significantly longer (medians: hydrofiber 12 days, SSD 6 and CN-SSD 4 days; p<0.01). The proportion of surgeries and the mean time to surgery was similar between the burn centers. CONCLUSIONS: This study compared different burn centers' treatment strategies for children with partial-thickness scalds and found a shorter time to wound healing in the CN-SSD group. Patients treated with hydrofiber had a shorter clinical period in comparison with the SSD and CN-SSD patients. The results of CN-SSD are promising and warrant further study. A prospective study is needed to gain full insight into the merits and drawbacks of the treatment strategies. This will allow clinicians to make full use of the strengths of particular treatments to benefit specific patients.


Subject(s)
Anti-Infective Agents, Local/therapeutic use , Burns/therapy , Carboxymethylcellulose Sodium/therapeutic use , Cerium/therapeutic use , Silver Sulfadiazine/therapeutic use , Adolescent , Burns/pathology , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Length of Stay , Male , Netherlands , Proportional Hazards Models , Retrospective Studies , Trauma Severity Indices , Wound Healing
3.
Work ; 18(1): 23-7, 2002.
Article in English | MEDLINE | ID: mdl-12441588

ABSTRACT

OBJECTIVES: To establish inter- and intra-rater reliability of observations in a functional capacity evaluation. BACKGROUND: Functional capacity evaluations are used to assess a person's functional capacity as it relates to work. Lifting and carrying are important aspects of a functional capacity evaluation. An evaluator determines the patient's levels of effort through standardized observations. Questions remain with regards to the reliability of these observations. METHODS: Four healthy subjects were videotaped while performing two lifts and four carries with progressive loads. The videotape was scrambled randomly and viewed twice by 3 physical therapists and 2 occupational therapists. The evaluators determined the amount of effort it required (light, medium, heavy, and maximum). The inter- and intra-rater reliability of the observations was expressed by means of percentage agreement. RESULTS: Inter-rater reliability ranged 87-96%, intra-rater reliability ranged 93-97%. CONCLUSION: The results indicate that by means of standardized observations, therapists can reliably determine effort level during lifting and carrying in healthy subjects, and thus affirm the findings of other studies of similar design.


Subject(s)
Biomechanical Phenomena , Lifting , Work Capacity Evaluation , Adult , Female , Humans , Male , Observer Variation , Physical Exertion , Reproducibility of Results
4.
Arch Phys Med Rehabil ; 82(8): 1099-105, 2001 Aug.
Article in English | MEDLINE | ID: mdl-11494190

ABSTRACT

OBJECTIVE: To assess the short-term outcome of a back school program for patients suffering from chronic, nonspecific low back pain (LBP). DESIGN: Quasi-experimental cohort study with a waiting list control group. SETTING: Dutch rehabilitation department. PARTICIPANTS: Experimental group (n = 14) participating in the back school program and a waiting list control group (n = 10). INTERVENTION: A back school program aimed to achieve optimal functional capacity and functional health status by teaching participants to react appropriately to overload signals. MAIN OUTCOME MEASURES: Functional capacity assessed by the RAND-36 instrument; functional health status assessed by the Roland-Morris Disability Questionnaire; and static and dynamic lifting capacity, endurance, and range of motion assessed by objective measures. RESULTS: The experimental group significantly improved in functional capacity and functional health status, with a large power, likely attributable to adequate reactions to signals of overload. Significant differences existed between the 2 groups, with large powers for the main outcomes. CONCLUSION: The back school program improved the functional capacity and functional health status of patients with chronic, nonspecific LBP.


Subject(s)
Activities of Daily Living , Health Status , Lifting , Low Back Pain/rehabilitation , Patient Education as Topic , Adult , Analysis of Variance , Case-Control Studies , Chronic Disease , Female , Humans , Male , Netherlands , Random Allocation , Social Support , Surveys and Questionnaires
5.
Disabil Rehabil ; 23(8): 336-40, 2001 May 20.
Article in English | MEDLINE | ID: mdl-11374523

ABSTRACT

PURPOSE: To compare Quality of Life (QoL) between diabetic patients with (former or present) and without foot ulcers. METHODS: Two patient groups of comparable age, sex distribution, type distribution and duration of diabetes were studied. Fourteen patients with former or present, but clinically stable diabetic foot ulcers (DFUs) were studied. The control group was 24 unknown patients with DFUs. None of the participants had other diabetic complications or conditions that would potentially affect QoL. A diabetic foot risk score and QoL were assessed. QoL was scored with the RAND-36, the Barthel Score (ADL) and the Walking and Walking Stairs Questionnaire (WSQ). RESULTS: Marked and significant differences were found in physical functioning (p < 0.001), social functioning (p < 0.05), physical role (p < 0.001) and health experience (p < 0.05) between the two groups with the RAND-36 and the four subscales of the WSQ (all p < 0.001). On all these scales, QoL was significantly poorer in the study group. A correlation was found between the risk scores and QoL (physical functioning and physical role Spearman's r: -0.66, -0.56 and WSQ -0.63, -0.64, -0.67 and 0.71, respectively). CONCLUSION: Presence or history of DFUs has a large impact on physical role, physical functioning and mobility. Physical impairments especially influenced QoL. Probably, QoL can be increased by providing attention that will enhance mobility and by giving advice about adaptations and special equipment.


Subject(s)
Foot Ulcer , Quality of Life , Aged , Cross-Sectional Studies , Female , Foot Ulcer/rehabilitation , Health Status Indicators , Humans , Male , Middle Aged
6.
J Autoimmun ; 11(5): 457-63, 1998 Oct.
Article in English | MEDLINE | ID: mdl-9802929

ABSTRACT

Systemic lupus erythematosus (SLE) is characterized by generalized immune activation. Part of this might be explained by a decreased rate of apoptosis, possibly related to elevated levels of soluble Fas (sFas) which can inhibit Fas mediated apoptosis of lymphocytes. In order to substantiate the relation between levels of sFas and lymphocyte activation in SLE we monitored sFas levels, lymphocyte activation and disease activity in 25 SLE patients. SLEDAI scores were registered and sera were assayed for sFas levels by an enzyme-linked immunosorbent assay. Flow cytometry was used to monitor the state of activation of lymphocyte subsets. Eighteen healthy, age-matched volunteers served as controls. Soluble Fas levels were elevated in SLE patients (n=25) compared to healthy controls (n=18, P=0.002). Soluble Fas levels correlated with SLEDAI scores (r=0.45, P=0.02). Levels of sFas correlated with the percentages of activated B cells defined as CD20(+)CD38(+) cells (r=0.47, P=0.009). Percentages of CD20(+)CD38(+) cells were increased in quiescent SLE compared to healthy controls (P=0.003). The expression of activation markers on CD4(+) T lymphocytes (IL-2R, P=0.04; HLA-DR, P=0.01) and CD8(+) T lymphocytes (HLA-DR, P=0.007) was also increased in quiescent SLE compared to controls. Activation markers on all lymphocyte subsets tended to increase further during disease activity. No correlation was observed between percentages of activated T lymphocyte subsets and levels of sFas. In conclusion, soluble Fas levels are increased in SLE patients and correlate with disease activity as measured by the SLEDAI score and B and T cell subsets are activated even during quiescent SLE. Serum levels of sFas correlate with percentages of activated B cells but not with that of activated T cells.


Subject(s)
Lupus Erythematosus, Systemic/immunology , Lymphocyte Activation , Lymphocytes/immunology , fas Receptor/blood , Adult , Apoptosis/immunology , B-Lymphocyte Subsets/immunology , B-Lymphocyte Subsets/pathology , Case-Control Studies , Female , Humans , Lupus Erythematosus, Systemic/pathology , Lymphocytes/pathology , Male , Middle Aged , Solubility , T-Lymphocyte Subsets/immunology , T-Lymphocyte Subsets/pathology
7.
Clin Orthop Relat Res ; (328): 119-28, 1996 Jul.
Article in English | MEDLINE | ID: mdl-8653944

ABSTRACT

The aim of this study was to obtain insight into the electromyographic activity of the hip muscles after transfemoral amputation and to determine whether the cleaved hip muscles are still functional in locomotion. The electromyographic activity of the superficial hip muscles of both legs was studied in 11 men who had a unilateral transfemoral amputation. The intact muscles at the intact and amputated side showed the same sequence of activity as did those in healthy subjects, but during a longer period of time. The activity of the cleaved muscles with intact muscle fibers (gluteus maximus, tensor fasciae latae) was dependent on whether the iliotibial tract was reanchored. If the iliotibial tract was fixed, the same activity was found in the muscles of the patients as in those of healthy subjects. The activity of the cleaved, once biarticular, muscles (sartorius, rectus femoris, hamstring muscles, gracilis) was dependent on whether the muscles were reanchored and on the level of amputation. If the cleaved muscles were reanchored correctly, the muscles remained functional in locomotion in patients with an amputation in the distal half of the femur. In patients with high amputation levels, these muscles were almost continuously active; they probably play a role in fixing the socket.


Subject(s)
Amputation, Surgical , Gait/physiology , Hip Joint/physiology , Leg/surgery , Muscle, Skeletal/physiology , Adult , Amputees , Artificial Limbs , Electromyography , Female , Humans , Male , Middle Aged
8.
Clin Orthop Relat Res ; (319): 276-84, 1995 Oct.
Article in English | MEDLINE | ID: mdl-7554640

ABSTRACT

To learn about the changes appearing in hip muscles after an above-knee amputation, 3-dimensional reconstructions of the hip and thigh region of 12 patients with above-knee amputations were made based on transverse magnetic resonance images. In all patients, the amputations were done at least 2 years before the study and were necessitated by trauma or osteosarcoma. The results show that, at higher amputation levels, the geometry of the once-biarticular muscles was changed. The cleaved muscles (40%-60%) and the intact muscles (0-30%) at the amputated side were atrophied. The amount of atrophy of the intact muscles at the amputated side was related to stump length. To avoid an abduction contracture in 8 patients with amputations, the iliotibial tract was not fixed. In 4 of these 8 patients, a flexion contracture was visible. If the tract was not fixed, the hip extension torque of the gluteus maximus, which inserts into the tract, decreased. As a result, the risk of appearance of a flexion contracture increased because the strongest hip flexor (iliopsoas muscle) was not involved in the amputation. Abduction contracture could be avoided only if the hip adductors were fixed accurately, especially at higher amputation levels.


Subject(s)
Amputation, Surgical , Hip/pathology , Muscles/pathology , Muscular Atrophy/pathology , Adult , Artificial Limbs , Contracture/pathology , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Models, Anatomic , Thigh/surgery
9.
Arch Phys Med Rehabil ; 76(8): 736-43, 1995 Aug.
Article in English | MEDLINE | ID: mdl-7632129

ABSTRACT

OBJECTIVE: The prosthetic gait of unilateral transfemoral amputees. DESIGN: Case series. SETTING: Laboratory of Gait Analysis (GIGA-system of K-lab) in the Department of Rehabilitation of a university hospital. PATIENTS: Eleven men with transfemoral amputation (mean age 35.7 years) participated. The amputation was performed at least 2 years ago and was caused by trauma or osteosarcoma. MAIN OUTCOME MEASURES: Stride parameters as well as the patterns of motion of the trunk, hip, and knee joint. RESULTS: The amputees walked with a 29% lower vcomf than normal subjects. The amputees compensate the vrapid with their stride length rather than with their step rate. The amputees showed an asymmetrical walking pattern; the amputees stood a little longer on their intact leg than on their prosthetic leg. Four amputees showed an extreme lateral bending of the trunk toward the prosthetic side during the stance phase of the prosthetic leg. The rebound of the hip at the amputated side at heel strike was very small or absent. The intact knee was flexed at heel strike and remained in a flexed position during the entire stance phase. CONCLUSIONS: The amount of asymmetry of the walking pattern is related to the stump length. The amputees with highly atrophied hip-stabilizing muscles walked with an extreme lateral bending of the trunk toward the prosthetic side. There is no correlation between stride width and lateral bending of the trunk. Amputees with a short and medium stump length showed a fast transition from hip extension to hip flexion.


Subject(s)
Amputation, Surgical/rehabilitation , Artificial Limbs , Gait/physiology , Adult , Femur/surgery , Humans , Male , Middle Aged , Muscular Atrophy/physiopathology , Posture/physiology , Rotation
10.
Arch Phys Med Rehabil ; 74(5): 521-5, 1993 May.
Article in English | MEDLINE | ID: mdl-8489363

ABSTRACT

Walking is most efficient when the least energy is spent over a certain distance. In six normal male subjects and 11 males with above-knee amputation the comfortable self-selected walking speeds and the most metabolically efficient walking speeds were determined. For that purpose energy expenditure was measured per second and per meter at six incremental walking speeds. Heart and step rate were registrated also at each walking speed. The results showed that in subjects who have not undergone amputation the comfortable walking speed is the same as the most efficient walking speed. However, in the above-knee amputee group, the comfortable walking speed is lower than the most efficient walking speed. When both groups walked at their own efficient walking speed they had the same energy expenditure per second.


Subject(s)
Amputation, Surgical/rehabilitation , Energy Metabolism/physiology , Gait/physiology , Artificial Limbs , Exercise Test , Heart Rate/physiology , Humans , Leg , Male , Oxygen Consumption/physiology , Posture/physiology , Reference Values
SELECTION OF CITATIONS
SEARCH DETAIL
...