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Background: Given the significant changes in family formation through donation procedures, providing an optimal level of care that is responsive to the needs of mothers who get pregnant via oocyte donation is pivotal to improve their maternal role. Therefore, it is necessary to recognize the needs of oocyte donation mothers to address their specific needs. Objective: This study aimed to review the needs of women in their journey towards motherhood via oocyte donation. Materials and Methods: In this systematic review, which followed the updated Joanna Briggs Institute's methodological guidance for conducting a mixed methods systematic review, the quantitative observational and qualitative studies were searched through databases including PubMed, Web of Science, PsycINFO, the Cochran Library, and Google Scholar search engine. Letters to the editor, commentaries, magazine articles, articles without full text and abstracts presented in congresses were excluded. All English-language articles related to the needs of oocyte donation mothers, without time limitation, were reviewed. The eligible studies were critically appraised independently by 2 researchers. Results: 4649 records were identified from those 18 articles were finally included in the review. The needs of oocyte donation mothers comprised 8 categories: The need for special services in fertility clinics, the need to improve the quality of care, the need for emotional support and psychological consultation, information needs, the need for financial support, the need for disclosure counseling, educational needs, and the need for sociocultural and religious support. Conclusion: This review suggests various needs of oocyte donation mothers. The results can be used in carefully planning supportive programs for this vulnerable population.
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In this article, the robust fault detection and isolation (FDI) Kalman filter is extended based on stochastic event-triggered schedulers for discrete linear systems consisting of deterministic/stochastic unknown inputs with nonzero mean and colored measurement noise. In the proposed FDI method, first, a subspace of the main system that significantly attenuates disturbance effects is proposed. After that, the fusion method is proposed for dealing with the colored measurement-noise problem in designing the Kalman filter and preventing from leading to measurement noise with zero mean and zero covariance. The stochastic event-triggered schedulers are considered as Gaussian functions. Therefore, the Gaussian property of innovation sequence is preserved, and consequently, the recursive equation of the Kalman filter need not be extended based on approximation techniques. Finally, design parameters are chosen based on the convex optimization problem such that the lowest communication rate between the sensor node and FDI filter, and also the best FDI performance are achieved. The proposed FDI method is evaluated to detect and isolate stator interturn short circuit and broken rotor bars faults with unbalanced voltage as disturbance in three-phase induction motors.
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BACKGROUND: In recent years, the incidence of male infertility has increased worldwide. It is necessary to study the factors that influence male infertility in each area/region for better management. OBJECTIVE: To determine the factors affecting male infertility in the Iranian male population. MATERIALS AND METHODS: An online search was conducted in electronic databases including PubMed, Google Scholar, SID, and Scopus to identify articles on the factors associated with male infertility, published in English and Persian. The keywords used to perform the search included "factor", "epidemiology", "causes of infertility", and "male infertility". The search was conducted without a time restriction, up to April 2020. RESULTS: The search resulted in a total number of 691 studies. After an assessment of the articles, finally 14 studies were included in this study with a total number of 26,324 infertile males. The factors associated with male infertility included semen abnormalities, varicocele and testis disorder, smoking, exposure to heat, obesity, anabolic steroids, vascular abnormalities, anti-spermatogenesis factors, antidepressants, taking ranitidine and cimetidine, penile discharge and genital ulcers, painful micturition, occupational factors, alcohol, chronic disease, sexual disorder, Surgical and urological diseases, genetic factors and herpes infection. Among these, the semen and varicocele disorders were common in most studies. CONCLUSION: The present review suggests that the factors affecting male infertility in Iran are similar to those reported from other countries. The results of this study can be used in adopting appropriate strategies for infertility management in Iran.
ABSTRACT
One of the ways to reduce the risk of contaminated water consumption is to optimally locate the quality sensors. These sensors warn users in the case of contamination detection. Analyzing the actual conditions of the contamination which enters the network is faced with many uncertainties. These uncertainties include the dose of contamination, time and location of its entry which have received less attention. Also, the uncertainty in the nodes' water demand causes changes in the distribution and contamination diffusion within the network. The main impetus of the present study is to determine the optimal quality sensor locations in the water distribution network in order to reduce the damage caused by contaminated water consumption prior to the contamination event detection. For this purpose, a parameter is defined as the maximum possible damage for calculating which the vulnerability and importance of the nodes have been considered in addition to the uncertainties in the location and time of the contamination entry. The importance of each node differs from that of other ones. Ranking the importance of the nodes is influenced by both land use and covered population ratio. In this study, six scenarios are defined for the contamination event in the water distribution network. These scenarios consider the effects of varying pollutant dose and the contamination input from nodes which are prone to its entry. Also, the NSGA-II has been utilized in order to minimize the damage with minimum number of sensors. The proposed model is evaluated on a real network in Iran. The results indicate that adding only one or two contamination warning sensors to the proposed locations can lead to the decreasing damage caused by the contaminated water consumption from 54 to 82%. According to the proposed method, the best answer for scenarios 1-6 was obtained for 7, 6, 6, 2, 2 and 2 sensors, respectively. The results showed that the slope of the pollution rate diagram does not change much from 6 sensors upwards in the first three scenarios, and from 4 sensors upwards in the second three scenarios. In scenarios 1-3, with 7, 6 and 6 sensors, respectively, in different nodes, the best placement is for 203-224 equivalent attack population, and in scenarios 4-6, with sensors in nodes 4 and 43, the best placement is for 225-279 equivalent attack population.
Subject(s)
Water Quality , Water , Environmental Monitoring , Iran , Uncertainty , Water SupplyABSTRACT
BACKGROUND: There are controversial views on accepting a reproductive donation in the world. OBJECTIVE: This study aimed to determine the relationship between the sociocultural beliefs and infertile couples' attitude toward reproductive donation in Mashhad, Iran. MATERIALS AND METHODS: This descriptive correlational study was conducted out on 115 infertile couples visiting Milad Infertility Center in Mashhad, Iran with using convenience sampling. The research instruments were valid and reliable sociocultural beliefs and attitude questionnaires, which were completed by the respondents on a self-report basis. RESULTS: The mean score of attitude toward reproductive donation in infertile women and men was 58.3 ± 12.6 and 57.8 ± 12.0, and the mean score of sociocultural beliefs in infertile women and men was 67.7 ± 11.5 and 67.6 ± 12.4, respectively. There was a direct correlation between sociocultural beliefs and attitude toward reproductive donation in infertile women (p < 0.001) and men (p < 0.001), that is, women and men with a higher score of sociocultural beliefs had a higher score of attitude as well. A direct correlation was also seen between sociocultural beliefs and infertile women and men's public attitude, their attitude towards genetic bound between parents and children, their attitude regarding the issue of confidentiality of the donation process, as well as attitude in relation to oocyte donation, embryo donation, and surrogacy (p < 0.001). CONCLUSION: The findings suggest that sociocultural beliefs that surround reproductive donation could influence infertile couple's attitude toward accepting these therapeutic alternatives in infertile couples. It is therefore recommended to take steps to incorporate sociocultural beliefs into the routine care of infertile couples with the help of social media to give them ability for making more pragmatic decision in relation to their chosen options.
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Familial Colorectal Cancer Type X (FCCTX) is a type of hereditary nonpolyposis colorectal cancer in accordance to Amsterdam criteria-1 for Lynch syndrome, with no related mutation in mismatch repair gene. FCCTX is microsatellite stable and is accounted for 40% of families with Amsterdam criteria-1 with a high age of onset. Thus, the carcinogenesis of FCCTX is different compared to Lynch syndrome. In addition to the microsatellite stability and the presence of less predominant tumors in proximal colon, various clinical features have also been associated with FCCTX in comparison with Lynch syndrome such as no increased risk of extra-colonic cancers, older age of diagnosis and higher adenoma/carcinoma rate. Genetic etiology of this type of cancer which is autosomal dominant is unknown. In this review, we focus on the genes and their variants identified in this type of CRC. In order to find out the correlation between FCCTX and various genes database such as PubMed and PMC, search engine such as Google scholar and portals such as Springer and Elsevier have been searched. Based on our literature search, several studies suggest that FCCTX is a heterogeneous type of disease with different genetic variants. Recent studies describe the correlation between FCCTX and genes such as BRCA2, SEMA4, NTS, RASSF9, GALNT12, KRAS, BRAF, APC, BMPR1A, and RPS20. Considering the fact that BRCA2 has the highest mutation rate (60%) and is one of the most crucial DNA repair genes, it will be considered as a big role player in this type of cancer in comparison with other genes.
