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1.
Indian J Dermatol ; 54(4): 380-1, 2009.
Article in English | MEDLINE | ID: mdl-20101345

ABSTRACT

Cutaneous metastasis from ovarian carcinoma is relatively uncommon in clinical practice. We report the case of the woman who presented to us with clitoral nodules and skin nodules. Histopathological examination of nodules confirmed the diagnosis of metastasis of an ovarian carcinoma. Despite poor prognosis, the patient responded and survived well beyond the expected four months survival of similar cases.

2.
Gynecol Obstet Invest ; 67(1): 20-4, 2009.
Article in English | MEDLINE | ID: mdl-18824861

ABSTRACT

AIMS: To determine the recurrent convulsion rate using low-dose magnesium sulphate regime in eclampsia and to identify toxicity and complications with clinical parameters. METHODS: Prospective study with two different magnesium sulphate regimes in two slightly clinically different subgroups. Group A that came directly to our hospital and group B who had already received an injection of diazepam or Phenergan at the referring hospital. Group A received 10 g and group B 6 g loading dose of magnesium sulphate. Both groups received 4 g maintenance dose every 4 h. RESULTS: Out of 95 eclamptic patients, only one woman in group B had recurrent convulsion. All women maintained normal respiratory rates. 39 (41.1%) women had absent knee jerks on at least one occasion when the maintenance dose was omitted. Urinary output was more than 30 ml/h in 92 (96.8%) women. In 5 women, maintenance dose had to be augmented to 5 g as reflexes were exaggerated. CONCLUSION: The low-dose regime appears to control and prevent convulsions effectively in Indian women. Clinical monitoring appears to be sufficient. We hope to be able to reassure health professionals at primary and secondary level hospitals about the safety of magnesium.


Subject(s)
Anticonvulsants/administration & dosage , Eclampsia/drug therapy , Eclampsia/physiopathology , Magnesium Sulfate/administration & dosage , Seizures/etiology , Seizures/prevention & control , Anticonvulsants/adverse effects , Female , Humans , Magnesium Sulfate/adverse effects , Pregnancy , Prospective Studies
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