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J Trop Pediatr ; 62(2): 131-8, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26705331

ABSTRACT

BACKGROUND: : Treatment outcomes of tuberculosis (TB) in children are rarely evaluated by most national TB programmes in sub-Saharan Africa. This study evaluated the treatment outcomes of children treated for TB in Lagos State, Nigeria. METHODS: A retrospective review of programme data of the Lagos state TB and the Leprosy control programme in Nigeria from 1 January 2012 to 31 December 2012. Treatment outcomes were categorized according to the national TB guidelines. RESULTS: A total of 535 cases of childhood TB were notified in 2012, representing 6.3% of the total TB cases notified in Lagos state in 2012. The prevalence of TB/HIV co-infection was 29%. The treatment success rate was 79.2% in TB/HIV-negative children compared with 73.4% in TB/HIV-positive children (p = 0.1268). Children <1 year had the worst treatment outcomes (p < 0.001). CONCLUSION: There is a need to intensify effort at improving notification and treatment outcomes in children.


Subject(s)
Antitubercular Agents/therapeutic use , Coinfection , Disease Notification/statistics & numerical data , HIV Infections/complications , Mycobacterium tuberculosis/isolation & purification , Tuberculosis/drug therapy , AIDS-Related Opportunistic Infections/complications , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/epidemiology , Adolescent , Child , Child, Preschool , Coinfection/epidemiology , Female , HIV Infections/epidemiology , Humans , Infant , Infant, Newborn , Male , Nigeria/epidemiology , Population Surveillance , Prevalence , Retrospective Studies , Sputum/microbiology , Treatment Outcome , Tuberculosis/diagnosis , Tuberculosis/epidemiology , Tuberculosis/microbiology
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