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6.
Z Alternsforsch ; 34(6): 503-10, 1980.
Article in German | MEDLINE | ID: mdl-7210711

ABSTRACT

In 20 persons in old age and in 20 young persons the immunization with 0,5 ml of a vaccine (tetanus toxoid) was performed. The cell--immediated immunity of lymphocytes of these probands were investigated on the 0,7 21. and 28. day by lymphocyte-transformation test and E-rosette test. The boostering followed after 21 days with the same dose of the vaccine. It was found that the spontaneous transformation rate in T-lymphocytes in old age compared to the young age was duplicated. The stimulation with PHA (Phytämagglutinin) showed no significant differences while the specific cellular reactivity of the T-cells in old age is delayed and reduced compared to the T-cells in young age.


Subject(s)
Immunity, Cellular , Tetanus Toxoid/immunology , Adolescent , Adult , Aged , Humans , Immunization , Lymphocyte Activation , Male , Rosette Formation
8.
Z Alternsforsch ; 35(3): 211-3, 1980.
Article in German | MEDLINE | ID: mdl-7456505

ABSTRACT

It was established, that there gives no significant correlations between LTT, MMHT and the intracutanous skin-test. The results show, how multifarious and self-contained immunological reactions can be. The results show too, that the tuberculosis infection (tuberculin skin test) from people after the 60th living year is very lower (64%) compared to the people in the 40th living year.


Subject(s)
Immunity, Cellular , Aged , Cell Migration Inhibition , Geriatrics , Humans , Lymphocyte Activation , Macrophages/immunology , Middle Aged , Tuberculin Test
10.
Arch Geschwulstforsch ; 49(2): 168-74, 1979.
Article in German | MEDLINE | ID: mdl-475553

ABSTRACT

Cell mediated immune reactions take an increasing part for the progress of malignant tumors besides numerous other factors. With support of the lymphocyte transformation test a significant difference was pointed out between orofacial tumors with long course and a control group of healthy persons by means of the interpretation of the PHA (phythemagglutinin)-stimulation. These results are to find indicated also in comparison of the antigen preparation with candidin in tumors with long course.


Subject(s)
Carcinoma, Squamous Cell/immunology , Lymphocyte Activation , Mouth Neoplasms/immunology , Candida/immunology , Humans , Neoplasm Metastasis , Neoplasm Recurrence, Local , Phytohemagglutinins , Tuberculin Test
17.
Article in German | MEDLINE | ID: mdl-198997

ABSTRACT

In the last years cell mediated immune reactions against the antigens of human carcinomas have obtained an increasing importance. With the lymphocyte transformation tests was found on the estimate of the PHA (phythemagglutinin)-stimulation a significant difference of the T-cell stimulation of patients with squamous cell carcinoma of the orofacial region opposite to a comparison group of healthy patients.


Subject(s)
Adenocarcinoma, Mucinous/immunology , Carcinoma, Squamous Cell/immunology , Lymphocyte Activation , Mouth Neoplasms/immunology , Humans , Immunosuppression Therapy , Lectins , Prognosis , T-Lymphocytes/immunology
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