ABSTRACT
Dynamic Light Scattering (DLS) is a widely used technique for measuring the size distributions of nano- and micro-particles dispersed in a liquid. The principle is based on the analysis of the temporal fluctuations of light scattered by the particles at a given scattering angle. However, single-angle DLS measurements may lack resolution and robustness, particularly for multimodal and/or polydisperse samples. Multi-angle Dynamic Light Scattering (MDLS) provides more robust, reproducible and accurate Particle Size Distributions (PSDs) than single-angle DLS. In this paper, a novel inversion method based on Bayesian inference is proposed for the estimation of the number PSD from MDLS measurements. The efficiency and robustness of this method is demonstrated through simulated and real data.
ABSTRACT
A temporal shortening by a factor higher than 10 of subnanosecond pulses launched into a low-birefringence optical fiber is achieved by polarization filtering at the output. By means of the theoretical approach, in good agreement with experimental measurements, the impact of the nonlinear polarization rotation and of the coherent coupling phenomena is pointed out.
ABSTRACT
Fluorescence in situ hybridization signals on human metaphase chromosomes are detected by a near-field scanning optical microscope. This makes it possible to localize and identify several fluorescently labeled genomic DNA fragments on a single chromosome with a resolution superior to traditional fluorescence microscopy. Several nucleic acid probes have been used. The hybridization signals are well resolved in the near-field fluorescence images, and the exact location of the probes can be correlated to the topography as it is afforded by the shear-force feedback.
