Aripiprazole and its adverse effects in the form of impulsive-compulsive behaviors: A systematic review of case reports.

Aripiprazole is an efficacious treatment for both the positive and negative symptoms of schizophrenia and is also commonly used as a mood stabilizer. It is associated with better tolerability compared with other antipsychotics. However, there are reports of patients who experience problem gambling, hypersexuality, obsessive-compulsive symptoms, and other impulsive and/or compulsive behaviors as a result of aripiprazole administration and/or dosage increase. We aimed to do a systematic review of case reports published in this regard. After screening more than 6000 titles and abstracts in ten scientific search engines, we found 35 related records comprising 59 cases. The majority of cases (n = 42, 71.18%) were male, the mean age was 33.83 years (± 13.40), and the average daily dose of aripiprazole was 11.63 mg (± 6.94). The results of our review showed that the most frequently published impulsivity adverse effect of aripiprazole is gambling, followed by hypersexuality, obsessive-compulsive symptoms/disorder, problem eating, trichotillomania, problem shopping, and kleptomania. These symptoms were experienced both by patients who had previous problems in these areas and those who did not. In the majority of cases, the symptoms appeared within 30 days after aripiprazole administration started and ceased within 30 days of its discontinuation and/or dose decrease. Clinicians should be aware of impulsivity adverse effects, monitor them, and educate both patients and the family about them.

Potential risk and protective factors related to problematic social media use among adolescents in Iran: A latent profile analysis.

This study aimed to assess Problematic Social Media Use (PSMU) among Iranian adolescents and explore potential risk and protective factors. In the present cross-sectional study, 3375 Iranian adolescents were recruited online and completed questionnaires. Latent profile analysis (LPA) was performed to identify groups with various levels of PSMU. Indicator variables included standardized factor scores for PSMU, attention-deficit/hyperactivity disorder, sensation-seeking, internet addiction, loneliness, social anxiety, internalizing symptoms, social support and self-esteem. Five groups were identified relating to severities of PSMU and other factors: low-risk: n = 823 (24.4 %); low-to-moderate-risk: n = 835 (24.7 %); moderate-risk: n = 630 (18.7 %); moderate-to-high-risk: n = 584 (17.3 %); high-risk: n = 503 (14.9 %). Multiple factors, including sensation-seeking, internalizing symptoms, social anxiety, loneliness, internet addiction, attention-deficit/hyperactivity disorder, low self-esteem and low perceived social support, statistically predicted PSMU. The current findings may help identify Iranian adolescents who are particularly vulnerable to PSMU and assist in intervention development.

The Big-five personality traits and their link to problematic and compensatory Facebook use: A systematic review and meta-analysis.

Social networking sites are widespread worldwide, and Facebook is the leading platform in terms of the number of users, laying the ground for potential problematic use. However, problematic Facebook use does not occur for most users but only for a minority. Previous research has found an association between the Big-five personality traits and problematic Facebook use, but the direction of these associations remains controversial. We aimed to fill this gap in knowledge through a systematic review and meta-analysis comprising 425 effect-sizes (78 studies) and 39,930 individuals (females = 33 % to 89 %; age range = 17 to 48 years). Extraversion and neuroticism were associated with higher daily and weekly hours spent on Facebook, while conscientiousness was negatively associated with higher daily hours and not weekly hours. However, when time spent on Facebook was assessed by validated questionnaires, different patterns of associations were observed. Except for the non-significant role of extraversion, the other personality traits were negatively associated with problematic Facebook use, while neuroticism was positively associated. When using different assessment tools was considered, extraversion remained non-significant, but different association patterns were observed. Moreover, for compensatory Facebook use, all personality traits were negatively associated with it, whereas neuroticism exhibited a positive association. Different patterns of associations in terms of strength and direction were observed depending on samples and measures characteristics; thus, definitive conclusions on the direction of the associations are impossible to draw at present. A more robust conceptualization and assessment of problematic Facebook use, as well as time spent on it, is required. Implications, limitations, and future directions are discussed.

The Big Five personality traits and online gaming: A systematic review and meta-analysis.

Online gaming has become an essential form of entertainment with the advent of technology and a large sway of research has been undertaken to understand its various permutations. Previous reviews have identified associations between the Big Five personality traits and online gaming, but a systematic review and meta-analysis on the association between these constructs has yet to be undertaken. In the current study we aimed to fill this gap in the literature through a systematic review and meta-analysis comprising of 17 studies and 25,634 individuals (AgeMean = 26.55, males = 75%). The findings showed that agreeableness, extraversion, openness to experience, and neuroticism were not ubiquitously associated with online gaming. The findings showed that only conscientiousness, across samples, had a protective role in online gaming. Furthermore, there were non-significant variations in the Big Five personality traits associations with online gaming when comparing gamers to the general population, younger versus older participants, casual versus 'hardcore' gamers, and high versus low traits (with the exception of neuroticism). As a result of our observations, the underlying mechanisms of individual differences in online gaming remain unclear. Limitations and future directions for research are discussed.