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1.
Nanotechnology ; 35(12)2024 Jan 04.
Article in English | MEDLINE | ID: mdl-38064741

ABSTRACT

Gallium oxide (Ga2O3) is a promising wide bandgap semiconductor that is viewed as a contender for the next generation of high-power electronics due to its high theoretical breakdown electric field and large Baliga's figure of merit. Here, we report a facile route of synthesizingß-Ga2O3via direct oxidation conversion using solution-processed two-dimensional (2D) GaS semiconducting nanomaterial. Higher order of crystallinity in x-ray diffraction patterns and full surface coverage formation in scanning electron microscopy images after annealing were achieved. A direct and wide bandgap of 5 eV was calculated, and the synthesizedß-Ga2O3was fabricated as thin film transistors (TFT). Theß-Ga2O3TFT fabricated exhibits remarkable electron mobility (1.28 cm2Vs-1) and a good current ratio (Ion/Ioff) of 2.06 × 105. To further boost the electrical performance and solve the structural imperfections resulting from the exfoliation process of the 2D nanoflakes, we also introduced and doped graphene inß-Ga2O3TFT devices, increasing the electrical device mobility by ∼8-fold and thereby promoting percolation pathways for the charge transport. We found that electron mobility and conductivity increase directly with the graphene doping concentration. From these results, it can be proved that theß-Ga2O3networks have excellent carrier transport properties. The facile and convenient synthesis method successfully developed in this paper makes an outstanding contribution to applying 2D oxide materials in different and emerging optoelectronic applications.

2.
Opt Lett ; 39(4): 805-8, 2014 Feb 15.
Article in English | MEDLINE | ID: mdl-24562211

ABSTRACT

In this work p-ZnO/n-GaN heterojunction diodes were directly formed on the Si substrate by a combination of cost-effective solgel spin-coating and thermal annealing treatment. Spin-coated n-ZnO films on InN/GaN/Si wafers were converted to p-type polarity after thermal treatment of proper annealing durations. X-ray diffraction (XRD) analysis reveals that InN-codoped ZnO films have grown as the standard hexagonal wurtzite structure with a preferential orientation in the (002) direction. The intensity of the (002) peak decreases for a further extended annealing duration, indicating the greater incorporation of dopants, also confirmed by x-ray photoelectron spectroscopy and low-temperature photoluminescence. Hall and resistivity measurements validate that our p-type ZnO film has a high carrier concentration of 3.73×10¹7 cm⁻³, a high mobility of 210 cm²/Vs, and a low resistivity of 0.079 Ωcm. As a result, the proposed p-ZnO/n-GaN heterojunction diode displays a well-behaving current rectification of a typical p-n junction, and the measured current versus voltage (I-V) characteristic is hence well described by the modified Shockley equation. The research on the fabrication of p-ZnO/n-GaN heterojunctions shown here generates useful advances in the production of cost-effective ZnO-based optoelectronic devices.


Subject(s)
Gallium/chemistry , Indium/chemistry , Semiconductors , Zinc Oxide/chemistry , Cost-Benefit Analysis , Feasibility Studies , Semiconductors/economics , Temperature
3.
Dev Cell ; 3(6): 877-87, 2002 Dec.
Article in English | MEDLINE | ID: mdl-12479812

ABSTRACT

The mechanisms by which prolactin controls proliferation of mammary epithelial cells (MECs) and morphogenesis of the breast epithelium are poorly understood. We show that cyclin D1(-/-) MECs fail to proliferate in response to prolactin and identify IGF-2 as a downstream target of prolactin signaling that lies upstream of cyclin D1 transcription. Ectopic IGF-2 expression restores alveologenesis in prolactin receptor(-/-) epithelium. Alveologenesis is retarded in IGF-2-deficient MECs. IGF-2 and prolactin receptor mRNAs colocalize in the mammary epithelium. Prolactin induces IGF-2 mRNA and IGF-2 induces cyclin D1 protein in primary MECs. Thus, IGF-2 is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.


Subject(s)
Cell Division/genetics , Cyclin D1/deficiency , Epithelial Cells/metabolism , Gene Expression Regulation, Developmental/genetics , Insulin-Like Growth Factor II/metabolism , Mammary Glands, Animal/embryology , Prolactin/metabolism , Animals , Breast Neoplasms/genetics , Carcinoma/genetics , Carrier Proteins , Cells, Cultured , Cyclin D1/genetics , Epithelial Cells/cytology , Epithelial Cells/drug effects , Female , Genes/drug effects , Genes/genetics , Genetic Testing , Insulin-Like Growth Factor II/genetics , Mammary Glands, Animal/cytology , Mammary Glands, Animal/metabolism , Membrane Glycoproteins , Mice , Mice, Knockout , Oligonucleotide Array Sequence Analysis , Progesterone/metabolism , Progesterone/pharmacology , Prolactin/genetics , Prolactin/pharmacology , RANK Ligand , RNA, Messenger/genetics , RNA, Messenger/metabolism , Receptor Activator of Nuclear Factor-kappa B , Receptors, Progesterone/deficiency , Receptors, Progesterone/genetics , Signal Transduction/genetics
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