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1.
Health Care Manag Sci ; 24(4): 716-741, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34031792

ABSTRACT

Early identification of resource needs is instrumental in promoting efficient hospital resource management. Hospital information systems, and electronic health records (EHR) in particular, collect valuable demographic and clinical patient data from the moment patients are admitted, which can help predict expected resource needs in early stages of patient episodes. To this end, this article proposes a data mining methodology to systematically obtain predictions for relevant managerial variables by leveraging structured EHR data. Specifically, these managerial variables are: i) Diagnosis categories, ii) procedure codes, iii) diagnosis-related groups (DRGs), iv) outlier episodes and v) length of stay (LOS). The proposed methodology approaches the problem in four stages: Feature set construction, feature selection, prediction model development, and model performance evaluation. We tested this approach with an EHR dataset of 5,089 inpatient episodes and compared different classification and regression models (for categorical and continuous variables, respectively), performed temporal analysis of model performance, analyzed the impact of training set homogeneity on performance and assessed the contribution of different EHR data elements for model predictive power. Overall, our results indicate that inpatient EHR data can effectively be leveraged to inform resource management on multiple perspectives. Logistic regression (combined with minimal redundancy maximum relevance feature selection) and bagged decision trees yielded best results for predicting categorical and numerical managerial variables, respectively. Furthermore, our temporal analysis indicated that, while DRG classes are more difficult to predict, several diagnosis categories, procedure codes and LOS amongst shorter-stay patients can be predicted with higher confidence in early stages of patient stay. Lastly, value of information analysis indicated that diagnoses, medication and structured assessment forms were the most valuable EHR data elements in predicting managerial variables of interest through a data mining approach.


Subject(s)
Electronic Health Records , Machine Learning , Data Mining , Hospitals , Humans , Logistic Models
2.
Health Syst (Basingstoke) ; 10(2): 138-161, 2020 Mar 01.
Article in English | MEDLINE | ID: mdl-34104432

ABSTRACT

Structured data formats are gaining momentum in electronic health records and can be leveraged for decision support and research. Nevertheless, such structured data formats have not been explored for clinical coding, which is an essential process requiring significant manual workload in health organisations. This article explores the extent to which fully structured clinical data can support assignment of clinical codes to inpatient episodes, through a methodology that tackles high dimensionality issues, addresses the multi-label nature of coding and optimises model parameters. The methodology encompasses transformation of raw data to define a feature set, build a data matrix representation, and testing combinations of feature selection methods with machine learning models to predict code assignment. The methodology was tested with a real hospital dataset and showed varying predictive power across codes, while demonstrating the potential of leveraging structuring data to reduce workload and increase efficiency in clinical coding.

3.
Appl Clin Inform ; 7(4): 1135-1153, 2016 12 07.
Article in English | MEDLINE | ID: mdl-27924347

ABSTRACT

BACKGROUND: EHR systems have high potential to improve healthcare delivery and management. Although structured EHR data generates information in machine-readable formats, their use for decision support still poses technical challenges for researchers due to the need to preprocess and convert data into a matrix format. During our research, we observed that clinical informatics literature does not provide guidance for researchers on how to build this matrix while avoiding potential pitfalls. OBJECTIVES: This article aims to provide researchers a roadmap of the main technical challenges of preprocessing structured EHR data and possible strategies to overcome them. METHODS: Along standard data processing stages - extracting database entries, defining features, processing data, assessing feature values and integrating data elements, within an EDPAI framework -, we identified the main challenges faced by researchers and reflect on how to address those challenges based on lessons learned from our research experience and on best practices from related literature. We highlight the main potential sources of error, present strategies to approach those challenges and discuss implications of these strategies. RESULTS: Following the EDPAI framework, researchers face five key challenges: (1) gathering and integrating data, (2) identifying and handling different feature types, (3) combining features to handle redundancy and granularity, (4) addressing data missingness, and (5) handling multiple feature values. Strategies to address these challenges include: cross-checking identifiers for robust data retrieval and integration; applying clinical knowledge in identifying feature types, in addressing redundancy and granularity, and in accommodating multiple feature values; and investigating missing patterns adequately. CONCLUSIONS: This article contributes to literature by providing a roadmap to inform structured EHR data preprocessing. It may advise researchers on potential pitfalls and implications of methodological decisions in handling structured data, so as to avoid biases and help realize the benefits of the secondary use of EHR data.


Subject(s)
Decision Support Systems, Clinical , Electronic Health Records , Models, Statistical , Data Mining , Humans
4.
J Digit Imaging ; 27(1): 33-40, 2014 Feb.
Article in English | MEDLINE | ID: mdl-23917864

ABSTRACT

The growing influx of patients in healthcare providers is the result of an aging population and emerging self-consciousness about health. In order to guarantee the welfare of all the healthcare stakeholders, it is mandatory to implement methodologies that optimize the healthcare providers' efficiency while increasing patient throughput and reducing patient's total waiting time. This paper presents a case study of a conventional radiology workflow analysis in a Portuguese healthcare provider. Modeling tools were applied to define the existing workflow. Re-engineered workflows were analyzed using the developed simulation tool. The integration of modeling and simulation tools allowed the identification of system bottlenecks. The new workflow of an imaging department entails a reduction of 41 % of the total completion time.


Subject(s)
Appointments and Schedules , Computer Simulation/statistics & numerical data , Diagnostic Imaging/statistics & numerical data , Efficiency, Organizational/statistics & numerical data , Patient Admission/statistics & numerical data , Radiology/organization & administration , Humans , Models, Organizational , Portugal , Workflow
5.
IEEE Trans Image Process ; 22(11): 4422-35, 2013 Nov.
Article in English | MEDLINE | ID: mdl-24057004

ABSTRACT

Dynamic contrast-enhanced magnetic resonance (DCE-MR) of the breast is especially robust for the diagnosis of cancer in high-risk women due to its high sensitivity. Its specificity may be, however, compromised since several benign masses take up contrast agent as malignant lesions do. In this paper, we propose a novel method of 3D multifractal analysis to characterize the spatial complexity (spatial arrangement of texture) of breast tumors at multiple scales. Self-similar properties are extracted from the estimation of the multifractal scaling exponent for each clinical case, using lacunarity as the multifractal measure. These properties include several descriptors of the multifractal spectra reflecting the morphology and internal spatial structure of the enhanced lesions relatively to normal tissue. The results suggest that the combined multifractal characteristics can be effective to distinguish benign and malignant findings, judged by the performance of the support vector machine classification method evaluated by receiver operating characteristics with an area under the curve of 0.96. In addition, this paper confirms the presence of multifractality in DCE-MR volumes of the breast, whereby multiple degrees of self-similarity prevail at multiple scales. The proposed feature extraction and classification method have the potential to complement the interpretation of the radiologists and supply a computer-aided diagnosis system.


Subject(s)
Algorithms , Breast Neoplasms/pathology , Gadolinium DTPA , Image Interpretation, Computer-Assisted/methods , Imaging, Three-Dimensional/methods , Magnetic Resonance Imaging/methods , Pattern Recognition, Automated/methods , Contrast Media , Female , Fractals , Humans , Image Enhancement/methods , Reproducibility of Results , Sensitivity and Specificity
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