1.
Org Lett
; 16(9): 2494-7, 2014 May 02.
Article
in English
| MEDLINE
| ID: mdl-24754303
ABSTRACT
A rhodium(III)-catalyzed oxidative olefination of 1,2-disubstituted arylhydrazines with alkenes via sp(2) C-H bond activation followed by an intramolecular aza-Michael reaction is described. This strategy allows the direct and efficient construction of highly substituted 2,3-dihydro-1H-indazole scaffolds.
Subject(s)
Alkenes/chemistry , Hydrazines/chemistry , Indazoles/chemical synthesis , Rhodium/chemistry , Catalysis , Indazoles/chemistry , Molecular Structure , Oxidation-Reduction , Oxidative Coupling
2.
Chem Commun (Camb)
; 50(18): 2350-2, 2014 Mar 04.
Article
in English
| MEDLINE
| ID: mdl-24448389
ABSTRACT
The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.
