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1.
Ned Tijdschr Geneeskd ; 160: D502, 2016.
Article in Dutch | MEDLINE | ID: mdl-27581866

ABSTRACT

Non-adherence occurs at any age, in all chronic diseases, and has a major impact on clinical outcomes. Non-adherence is primarily determined by perceptions of illness and medication beliefs. During puberty, adolescents attain independence from their parents and attach to their peers. This complicates successful self-management of chronic illness, because the adolescents avoid standing out from their peers. Discussion of barriers hindering successful self-management in adolescents can be promoted by seeing the patient alone, without the parents being present, and by acknowledging the patient's independence and responsibilities.


Subject(s)
Adolescent Behavior/psychology , Patient Compliance/psychology , Self Care/psychology , Adolescent , Chronic Disease , Humans , Parent-Child Relations , Physician-Patient Relations , Psychology, Adolescent , Social Behavior
2.
Ned Tijdschr Geneeskd ; 150(26): 1433-8, 2006 Jul 01.
Article in Dutch | MEDLINE | ID: mdl-16875262

ABSTRACT

Investigations were carried out in 2 women of 17 and 18 years with primary amenorrhea, normal external female genitalia and delayed secondary sexual characteristics, for the reasons for delayed puberty. The 17-year-old patient had reduced values of FSH, LH and oestradiol. This disturbance in the hypothalamo-hypophysary axis was caused by hydrocephalus. Menarche occurred following drainage of the fluid. The 18-year-old patient had raised values ofFSH and LH and a lowered oestradiol value. There was therefore a disfunction existing at ovarian level, which appeared to be caused by an XX-gonadal dysgenesis. The patient was treated with hormones which led to breast development and menarche taking place. The cause ofprimary amenorrhea can mainly be divided into three categories: constitutional delayed puberty, delayed puberty due to hypogonadotropic hypogonadism, or delayed puberty due to hypergonadotropic hypogonadism. A carefully taken medical history, together with determination of the serum levels of FSH and LH, is helpful in differentiating between these categories. Subsequently, structured clinical management must be performed in order to approach the differential diagnosis of each of these categories, which will then be followed by the final diagnosis.


Subject(s)
Amenorrhea/etiology , Gonadal Dysgenesis, 46,XX/complications , Hydrocephalus/complications , Adolescent , Amenorrhea/blood , Diagnosis, Differential , Estradiol/blood , Female , Follicle Stimulating Hormone/blood , Humans , Luteinizing Hormone/blood
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