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Drugs and Sleep Apneas? A review of the French Pharmacovigilance database.
Linselle, Mélanie; Montastruc, François; Jantzen, Hélène; Valnet-Rabier, Marie-Blanche; Haramburu, Françoise; Coquerel, Antoine; Gouraud, Aurore; Perault-Pochat, Marie-Christine; Bagheri, Haleh; Montastruc, Jean-Louis.
Therapie ; 70(4): 347-50, 2015.
Article in English | MEDLINE | ID: mdl-25679185

ABSTRACT

The present work reviews the case reports of drug-induced sleep apnea recorded in the French pharmacovigilance database. Notifications are very rare (around 1/100 000 notifications). This paper shows that sleep apnea can be aggravated or revealed by some drugs. Main drugs involved were psychotropics (benzodiazepines, neuroleptics) and opioids.


Subject(s)
Adverse Drug Reaction Reporting Systems , Drug-Related Side Effects and Adverse Reactions/epidemiology , Sleep Apnea Syndromes/epidemiology , Adult , Aged , Databases, Factual , Female , France/epidemiology , Humans , Male , Middle Aged , Pharmacovigilance , Retrospective Studies , Sleep Apnea Syndromes/chemically induced
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