ABSTRACT
First experiments with nonaxisymmetric magnetic perturbations, toroidal mode number n=2, produced by newly installed in-vessel saddle coils in the ASDEX Upgrade tokamak show significant reduction of plasma energy loss and peak divertor power load associated with type-I edge localized modes (ELMs) in high-confinement mode plasmas. ELM mitigation is observed above an edge density threshold and is obtained both with magnetic perturbations that are resonant and not resonant with the edge safety factor profile. Compared with unperturbed type-I ELMy reference plasmas, plasmas with mitigated ELMs show similar confinement, similar plasma density, and lower tungsten impurity concentration.
ABSTRACT
A murine monoclonal antibody, WIM-8 with specificity for BoLA-w8, was generated after using an immunization protocol designed to reduce the response to bovine monomorphic determinants. BoLA-w8/w9 peripheral blood mononuclear (PBM) cells were incubated with an antiserum from mice immunized with BoLA-w10/w20 PBM cells. Splenocytes from a mouse that received three intravenous injections of the treated cells were fused with murine myelomas. A hybridoma supernatant with alloreactivity in ELISA against BoLA-w8 positive but not BoLA-w8 negative PBM cells was tested for lymphocytotoxicity in parallel with parous alloantisera. WIM-8, an IgG2b monoclonal antibody, identified the 44,000 dalton protein of the bovine MHC class I molecule present on Bos taurus and Bos indicus animals.
