ABSTRACT
The performance of professional tasks with a high cognitive, emotional, and even physiological demand, can cause a state of mental fatigue, which implies attentional alterations, greater errors in the tasks performed and a decrease in personal and work productivity caused by a deterioration of the cognitive control processes. The present study presents a mobile phone application named BAlert that allows monitoring and controlling the body's fatigue processes based on the scores obtained in the Stroop effect and the heart rate variability. A pilot study has been carried out with a sample of 63 adults who have used the application a total of 942 times. The results allow us to classify the subjects, by logistic regression analysis, in their fatigue levels in 74% of the occasions. These results highlight the importance of this mobile application to control work fatigue processes in different possible scenarios (military, health, sports, business, etc.).
ABSTRACT
Existe el último tiempo un aumento de la mortalidad en escolares y adolescentes por suicidio y muertes violentas, ocasionalmente relacionada con estrés psicosocial, conductas de riesgo y consumo de sustancias. Actualmente no hay disponible protocolos ni equipos especializados en el manejo familiar ni psicosocial. Objetivo: Dar a conocer mediante revisión bibliográfica factores predictores de riesgo y estrategias efectivas en el tratamiento de familias y cercanos al fallecido. Estudios previos sobre el impacto de la muerte nombran 3 grupos: muerte por causas naturales, por eventos traumáticos y por suicidio. Más del 50% de padres con muerte de hijo sufrieron alteraciones psicosociales y físicas. Factores predictores: aislamiento, sexo femenino. Resultados: No hay a la fecha estudios en Chile que evalúen el duelo por causas violentas. Hay un déficit de recomendaciones para el trabajo en colegios y familiares. Conclusiones: Existe un aumento en muerte de niños y adolescentes por causas violentas, cuyos factores predictores deberían ser tratados y evaluados para trabajar. Deben estructurarse pautas y guías para enfrentar el duelo a nivel familiar. Palabras clave: Muerte, Suicidio, Niño, Adolescente, Psicopatología.
Lately there has been an increase in mortality in children and adolescents due to suicide and violent deaths, occasionally related to psychosocial stress, risk behaviors and illegal substance use. Currently there are no protocols or teams specializing in psychosocial and family management. Objective: To present a review of risk predictors and effective treatment for families and kin of deceased children and adolescents. Previous studies about impact of death indicated 3 groups: death by natural causes, suicide and traumatic events. Over 50% of grieving parents suffered psychosocial and physical disorders. Predicting factors were: isolation, female gender. Results: At this time there are no studies in Chile to evaluate mourning due to violent causes. There is a shortage of recommendations for schools and family. Conclusions: There is an increase in death rates of children and adolescents from violent causes, whose predictors should be treated and evaluated to work. There should be structured guidelines and guidance to confront the family mourning.Key words: Death, Suicide, Child, Adolescent, Psychopathology
ABSTRACT
BACKGROUND: Embryo implantation failure is considered an important cause of infertility in women undergoing assisted reproductive protocols. Recent studies demonstrated that the cyclooxygenase-2 (COX-2) enzyme is implicated in biosynthesis of prostaglandins and play an important role in the molecular implantation mechanisms. According to this evidence, we evaluated the potential association between the -765G>C (rs20417) polymorphism at the COX-2 gene and the implantation failure susceptibility in a sample of Chilean women. METHODS: A total of 186 unrelated women matched by age were included in the present study, 106 patients (aged 31.9±4.17 y) with no history of successful pregnancy and a diagnosis of infertility undergoing assisted reproductive protocols and 80 healthy controls (aged 31.4 ± 4.05 y). The COX-2 -765G>C gene polymorphism was analyzed by PCR-RFLP. RESULTS: Genotype distribution and allelic frequencies for -765G>C polymorphism of COX-2 gene were significantly different between patients and controls (P=0.004 and P=0.002, respectively). The odds ratio for implantation failure associated to the -765C allelic variant was 2.14 (95% C.I., 1.35-3.39, P=0.00071). CONCLUSION: Our data suggest, by the first time, that the COX-2 -765G>C polymorphism is associated with recurrent implantation failure in Chilean women and may constituted a novel molecular biomarker of reproductive failure.
