1.
Neurology
; 25(9): 866-9, 1975 Sep.
Article
in English
| MEDLINE
| ID: mdl-1172211
ABSTRACT
Patients with Parkinson's disease are unable to adjust the firing rate of motor units that initiate contraction from zero to higher rates; the frequency modulation of motor units is not normal, but motor units recruit normally as effort is increased. Treatment with levodopa makes these motor units accessible to activation and frequency control. Elderly subjects also have difficulty in the activation of minimal contraction and in the maintenance of firing but to a significantly lesser degree than do parkinsonian patients. In this respect, the elderly patient and the parkinsonian patient are qualitatively similar.
Subject(s)
Levodopa/therapeutic use , Motor Neurons/physiology , Parkinson Disease/drug therapy , Aged , Humans , Levodopa/pharmacology , Motor Neurons/drug effects , Muscle Contraction/drug effects , Parkinson Disease/physiopathology , Physical Exertion , Tremor/drug therapy , Tremor/physiopathology
2.
Conn Med
; 38(8): 423-4, 1974 Aug.
Article
in English
| MEDLINE
| ID: mdl-4414051
3.
Rocky Mt Med J
; 71(1): 45-6, 1974 Jan.
Article
in English
| MEDLINE
| ID: mdl-4815717
Subject(s)
Brain Stem , Cerebellar Diseases , Polyradiculopathy , Adult , Brain Diseases , Humans , Male , Polyradiculopathy/classification , Syndrome
4.
Rocky Mt Med J
; 70(7): 42-4, 1973 Jul.
Article
in English
| MEDLINE
| ID: mdl-4197762
5.
Stroke
; 3(5): 632-81, 1972.
Article
in English
| MEDLINE
| ID: mdl-4652735
6.
Electroencephalogr Clin Neurophysiol
; 30(2): 159, 1971 Feb.
Article
in English
| MEDLINE
| ID: mdl-4100254
7.
Arch Neurol
; 16(4): 377-84, 1967 Apr.
Article
in English
| MEDLINE
| ID: mdl-4290103
8.
Arch Neurol
; 14(4): 369-77, 1966 Apr.
Article
in English
| MEDLINE
| ID: mdl-5906461