Bilateral Nonossifying Fibroma of the Mandible: A case report of a rare entity.

Nonossifying fibroma (NOF) is a benign lesion confined to the bone marrow and connective tissues without exhibiting osseous metaplasia. NOF of long bones in children is more common than its gnathic counterpart. Mandibular NOF is rare, and there is a paucity of information in the literature. NOF of the jaws clinically presents as a nodular, fibrous, asymptomatic, gingival, or alveolar mucosal enlargement, with or without facial swelling. NOF differs from the ossifying type by the presence of metastatic woven bone in ossifying type. This article reports an example of bilateral, multilocular, NOF of the mandible in a 15-year-old female patient with unilateral, asymptomatic facial asymmetry. The radiographic features were characteristic of NOF. It was treated successfully with surgical excision and curettage. A 2-year postoperative follow-up showed recurrence of the right lesion and needed secondary surgical intervention, and the tumor on the left side, however, healed well without recurrence.

A spotlight on application of microwave-assisted modifications of plant derived polymers in designing novel drug delivery systems.

Polymers are a fundamental part of numerous industries and can be conjugated with many other materials and components to have a vast array of products. Biomaterials have been extensively studied for their application in pharmaceutical formulation development, tissue engineering, and biomedical areas. However, the native form of many polymers has limitations concerning microbial contamination, susceptibility, solubility, and stability. Chemical or physical modifications can overcome these limitations by tailoring the properties of polymers to meet several requirements. The polymer modifications are interdisciplinary, cutting across conventional materials, physics, biology, chemistry, medicine, and engineering limitations. Microwave irradiation has become a well-established technique for a few decades to drive and promote chemical modification reactions. This technique allows ease of temperature and power control to perform the synthesis protocols efficiently. Additionally, microwave irradiation contributes to green and sustainable chemistry. In this contribution, microwave-assisted polymer modifications were described with a special focus on their application in developing several novel dosage forms.

Nanomaterials in Dentistry: Current Applications and Future Scope.

Nanotechnology utilizes the mechanics to control the size and morphology of the particles in the required nano range for accomplishing the intended purposes. There was a time when it was predominantly applied only to the fields of matter physics or chemical engineering, but with time, biological scientists recognized its vast benefits and explored the advantages in their respective fields. This extension of nanotechnology in the field of dentistry is termed 'Nanodentistry.' It is revolutionizing every aspect of dentistry. It consists of therapeutic and diagnostic tools and supportive aids to maintain oral hygiene with the help of nanomaterials. Research in nanodentistry is evolving holistically but slowly with the advanced finding of symbiotic use of novel polymers, natural polymers, metals, minerals, and drugs. These materials, in association with nanotechnology, further assist in exploring the usage of nano dental adducts in prosthodontic, regeneration, orthodontic, etc. Moreover, drug release cargo abilities of the nano dental adduct provide an extra edge to dentistry over their conventional counterparts. Nano dentistry has expanded to every single branch of dentistry. In the present review, we will present a holistic view of the recent advances in the field of nanodentistry. The later part of the review compiled the ethical and regulatory challenges in the commercialization of the nanodentistry. This review tracks the advancement in nano dentistry in different but important domains of dentistry.