Coated Urea Materials for Improving Yields, Profitability, and Nutrient Use Efficiencies of Aromatic Rice.

Intensive cultivation and introduction of input-responsive high-yielding varieties with application of major nutrients in rice-wheat rotation of Indo-Gangetic plains (IGPs) lead to multiple nutrient deficiencies. A survey of Indian soils has shown that 40% are deficient in available zinc (Zn), 33% in sulfur (S), and 33% in boron (B). Studies have indicated that application of these nutrients with major nutrients can improve the crop productivity. Keeping the importance of aromatic rice in view, coated-urea materials and their effects on rice yields, nitrogen (N), and Zn content in different parts and input economics are evaluated. Three field trials are conducted on aromatic rice to test boron-coated urea (BCU), sulfur-coated urea (SCU), and zinc-coated urea (ZnCU) in 2013 and 2014. Results indicate that the highest yields are obtained with 0.5% BCU, 5.0% SCU, and 2.5% ZnCU as zinc sulfate heptahydrate. These treatments increase grain yield by 13%, 25%, and 17.9% over prilled urea (PU). Moreover, 0.5% BCU, 5% SCU, and 2.5% ZnCU register the highest N, S, and Zn contents in bran, husk, grain, and straw. Coated-urea materials also improve use efficiencies and harvest index of N and Zn over PU. The findings of this study suggest that 0.5% boron, 5.0% sulfur, or 2.5% zinc-coated urea show improvement in returns and benefit-cost ratio in aromatic rice of western IGPs.

Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India.

BACKGROUND AND AIM: Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. METHODS: Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18-68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19-70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. RESULTS: RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1-69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. CONCLUSION: RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC.

Prevalence of hepatitis D virus infection among hepatitis B virus-infected individuals in India.

BACKGROUND: The prevalence of hepatitis D virus (HDV) infection among persons with hepatitis B virus (HBV) infection shows geographic variation and has declined in recent times in several regions. In India, studies during the 1990s showed highly variable anti-HDV prevalence rates among HBV-infected persons; however, data using molecular testing and recent data are not available. We therefore studied the prevalence of HDV infection in HBV-infected patients using tests for anti-HDV and HDV ribonucleic acid (RNA). METHODS: Two cohorts of patients with HBV infection were enrolled (cohort A, n = 150, January to December 2012; cohort B, n = 168, October 2013 to April 2014). Sera from cohort A were tested for IgG anti-HDV using three enzyme immunoassays and those from cohort B for IgG anti-HDV using an enzyme immunoassay and for HDV RNA using a real-time amplification assay. RESULTS: Of the 318 subjects (259 male; mean age 36.9 years), 161 (50.6 %) had chronic hepatitis B, 101 (31.8 %) had cirrhosis, 52 (16.3 %) had acute viral hepatitis, and 4 (1.3 %) had acute liver failure. In cohort A, all specimens tested negative for anti-HDV antibodies using all the three assays. In cohort B, all specimens tested negative for anti-HDV IgG as well as HDV RNA. CONCLUSION: Our data indicate that HDV infection is uncommon in northern India.