ABSTRACT
Tan solo en los últimos 50 años, la esperanza de vida ha aumentado en más de 20 años. Este aumento significativo de la longevidad se debe en parte a los avances de la medicina, las intervenciones de salud pública, la biotecnología y el desarrollo social y económico, que han permitido a las personas vivir más que en cualquier otro momento de la historia. En América Latina y el Caribe, la proporción de personas de 60 o más años de edad aumentará incluso en 18% durante el próximo decenio y para el 2050 se ubicará entre 25% y 30% de la población. Esta transición ocurrirá en 35 años, que es tan solo la mitad del tiempo que requirió en Estados Unidos y Canadá.
Subject(s)
Aging , Healthy Aging , Aged , Health of the Elderly , Latin America , Caribbean Region , Americas , COVID-19ABSTRACT
[EXTRACT]. In just the past 50 years, life expectancy has increased by more than 20 years. This significant increase in longevity is due in part to advances in medicine, public health interventions, biotechnology, and social and economic development that have made it possible for people to live longer than at any other time in history.
Subject(s)
Aging , Healthy Aging , Latin America , Caribbean Region , Americas , COVID-19Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Cholinergic Antagonists/adverse effects , Dementia/chemically induced , Muscarinic Antagonists/administration & dosage , Muscarinic Antagonists/adverse effects , Cholinergic Antagonists/administration & dosage , Alzheimer Disease/etiology , Histamine H1 Antagonists/administration & dosage , Histamine H1 Antagonists/adverse effects , Antidepressive Agents, Tricyclic/administration & dosage , Antidepressive Agents, Tricyclic/adverse effectsABSTRACT
RENAL PHYSIOLOGY IN THE HEALTHY OLDEST OLD HAS THE FOLLOWING CHARACTERISTICS, IN COMPARISON WITH THE RENAL PHYSIOLOGY IN THE YOUNG: a reduced creatinine clearance, tubular pattern of creatinine back-filtration, preserved proximal tubule sodium reabsorption and uric acid secretion, reduced sodium reabsorption in the thick ascending loop of Henle, reduced free water clearance, increased urea excretion, presence of medulla hypotonicity, reduced urinary dilution and concentration capabilities, and finally a reduced collecting tubules response to furosemide which expresses a reduced potassium excretion in this segment due to a sort of aldosterone resistance. All physiological changes of the aged kidney are the same in both genders.
