ABSTRACT
PURPOSE: The aim of this study was to investigate the influence of artificial tears containing either cationic nanoemulsion (CCN) or sodium hyaluronate artificial tears (SH) on early postoperative healing after modern surface refractive surgery. MATERIALS AND METHODS: In this multicenter, prospective, double-masked, parallel-group (1:1), comparative study, 129 patients (n = 255 eyes) were randomized to receive CCN (n = 128) or SH (n = 127) as an adjuvant treatment after either transepithelial photorefractive keratectomy (transPRK) or Epi-Bowman keratectomy (EBK). The patients' perspectives were gathered using the Ocular Surface Disease Index (OSDI) questionnaire, and uncorrected (UCVA), and corrected (BCVA) visual acuity were assessed before and one week and one month after the procedure. In addition, corneal epithelization and subjective assessment of visual blur and eye irritation on drop instillation were assessed at one week postoperatively. RESULTS: No statistically significant differences were found between two groups in age, spherical equivalent refractive error, UCVA, BCVA or OSDI scores before the procedure. There was also no difference between groups in UCVA one week and one month after the procedure. However, statistically significantly lower OSDI scores were found one week and one month after the procedure in the CCN group. Moreover, blurred vision after use of the eye drops was observed less frequently in the CCN group than in the SH group. CONCLUSIONS: The CCN and SH groups had similar postoperative UCVA. However the significantly lower OSDI scores and less frequently blurred vision after application of the eye drops in the CCN group suggest better subjective outcomes in this group.
ABSTRACT
PURPOSE: To evaluate results of treatment of choroidal neovascularization due to age-related macular degeneration with aflibercept in a group of patients representative for Polish population. MATERIAL AND METHODS: Three intravitreal injections of 2.0 mg of aflibercept were administrated to 48 eyes with active choroidal neovascularization at the four week intervals. In the evaluated population there were 19 eyes previously treated with other anti-VEGF drugs and 29 treatment naive eyes. RESULTS: The mean best corrected visual acuity at baseline in the entire group was 0.47. During the follow-up exam after the first injection, the best corrected visual acuity increased to 0.58. After the second and third injection, it reached the level of 0.62 and 0.63, respectively. Such improvement in visual acuity was accompanied by the reduction of central retinal thickness. Eyes with intraretinal fluid presence confirmed in baseline spectral domain optical coherence tomography had significantly lower best corrected visual acuity throughout the entire follow up. CONCLUSION: Three intravitreal aflibercept injections in eyes with neovascular age-related macular degeneration resulted in significant improvement of best corrected visual acuity and reduction of central retinal thickness both in eyes previously treated using other anti-VEGF drugs and newly diagnosed ones. aflibercept, neovascular age-related macular degeneration, choroidal neovascularization, anti-VEGF treatment, optical coherence tomography.
Subject(s)
Intravitreal Injections , Macular Degeneration/drug therapy , Receptors, Vascular Endothelial Growth Factor/administration & dosage , Recombinant Fusion Proteins/administration & dosage , Visual Acuity/drug effects , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Macular Degeneration/pathology , Male , Middle Aged , Poland , Retina/pathology , Tomography, Optical Coherence , Treatment OutcomeABSTRACT
The current paper presents a case of unique presentation of idiopathic uveal effusion syndrome. The 28 years old patient with combined bilateral choroidal and retinal detachment, recurrent in the left eye, underwent surgical procedures. He was treated with lamellar sclerectomy under the scleral flap in both eyes and another sclerectomy in the left eye later on. The apposition of the retina was achieved in both eyes and visual acuity improved significantly. Three months later, the patient developed anterior ischemic optic neuropathy in the right eye. In left eye after cataract phacoemulsification, persisted cystoid macular edema appeared.
Subject(s)
Choroid Diseases/diagnosis , Macular Edema/diagnosis , Optic Neuropathy, Ischemic/diagnosis , Retinal Detachment/diagnosis , Uveal Diseases/diagnosis , Adult , Choroid Diseases/surgery , Humans , Macular Edema/surgery , Male , Ophthalmologic Surgical Procedures/methods , Optic Neuropathy, Ischemic/surgery , Phacoemulsification/methods , Retinal Detachment/surgery , Syndrome , Uveal Diseases/surgeryABSTRACT
PURPOSE: To assess changes in axial length, corneal curvature in pseudophakia in children. MATERIAL AND METHODS: 104 patients (123 eyes) operated between January 1987 and December 1997 with congenital or traumatic cataract. Serial measurements were made of axial length and corneal curvature. RESULTS: The follow up time ranged from 2 to 10 years. The ranges of axial length changes were from 0,16 to 0,93 mm. Eyes in the first 6 years of life (group I) experienced more elongation than eyes in the older years (group II and III). The corneal curvature changes ranged from 0,02 to 0,05 mm. There was no significant difference between preoperative and postoperative corneal curvature. CONCLUSIONS: The pattern of axial elongation and corneal flattening was similar in the congenital and traumatic cataract groups to that observed in normal eyes. No significant retardation or acceleration of axial growth was found in the eyes implanted with IOLs, compared with normal eyes.
Subject(s)
Cornea/anatomy & histology , Cornea/physiopathology , Eye/anatomy & histology , Pseudophakia/diagnosis , Pseudophakia/physiopathology , Adolescent , Cataract/diagnosis , Cataract/physiopathology , Child , Child, Preschool , Female , Humans , Male , Retrospective Studies , Severity of Illness IndexABSTRACT
PURPOSE: To report refractive changes after cataract surgery and intraocular lens implantation in children. MATERIAL AND METHODS: 104 patients (123 eyes) operated between January 1987 and December 1997 with congenital or traumatic cataract. Refractive power in both operated and non operated eyes, were measured. RESULTS: The operated eyes tended to become myopic. Children, who underwent surgery in the first 6 years of life had a greater myopic shift than older children. The mean myopic shift ranged from -2.33 D to -0.51 D in operated eyes and from -1.05 D to -0.49 D in non operated eyes. CONCLUSIONS: Pseudophakia in children is predicted to result in a large quantity of myopic shift, particularly in very young children. This natural myopic shift is magnified by the optical effect of a high-power IOL.
