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1.
Indian J Pediatr ; 85(4): 295-299, 2018 04.
Article in English | MEDLINE | ID: mdl-29457208

ABSTRACT

Tobacco smoke, active or passive exposure was the major cause of preventable morbidity and mortality in the world during twentieth century and will continue to be the same in the twenty-first century also if the current trends continue. Both active and passive smoking are having significance in relation to child health. Exposure starts antenatally from placenta to the fetus and later phases through passive exposure to experimental and regular smoking and ultimately addiction and habitual smoking. Evidences are in favour of causal relationship with intrauterine growth restriction, sudden infant death syndrome, decreased pulmonary function, increased risk for respiratory tract infection, otitis media, wheeze, asthma, neurobehavioral disorders, cleft palate and triggering pathogenesis of fetal and childhood onset of adult diseases, especially pulmonary and cardio vascular diseases. All these facts stress the importance of behavioral changes in the population as well as stringent public health measures and legislation for ensuring smoke free work places, public places and households for children. M POWER- Package by WHO is a novel global initiative taking us closer to the target of achieving tobacco free environment for children in the near future.


Subject(s)
Child Health , Tobacco Smoke Pollution/prevention & control , Adult , Child , Female , Humans , Infant , Pregnancy , Smoke , Smoking
2.
J Med Microbiol ; 62(Pt 4): 545-552, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23288429

ABSTRACT

Dengue fever is re-emerging as a major scourge in south-east Asian countries, affecting about 50-100 million people and causing about 25,000 deaths annually. The Indian population as a whole is at risk of succumbing to this disease. This study genetically characterized viruses causing dengue infection in Kerala, one of the worst affected states of the country, during the disease outbreaks in 2008-2010. All four serotypes of dengue virus (DENV), DENV-1, DENV-2, DENV-3 and DENV-4, were found to be prevalent in the state. The genotypes recognized for these were III, IV, III and I, respectively. Phylogenetic analysis showed that the re-emergence of serotype DENV-4 reported in Maharashtra and Andhra Pradesh recently is spreading to different regions of the country. The circulation of all four DENV serotypes in Kerala may lead to an increase in the prevalence of more severe complications of this emerging disease, such as dengue haemorrhagic fever and dengue shock syndrome.


Subject(s)
Dengue Virus/classification , Dengue Virus/genetics , Dengue/epidemiology , Dengue/virology , Genetic Variation , RNA, Viral/genetics , Cluster Analysis , Dengue Virus/isolation & purification , Humans , India/epidemiology , Molecular Epidemiology , Molecular Sequence Data , Phylogeography , Prevalence , Sequence Analysis, DNA , Serotyping
3.
Asia Pac J Clin Nutr ; 11(1): 33-5, 2002.
Article in English | MEDLINE | ID: mdl-11890636

ABSTRACT

Iodine is one of the essential micro-elements required for normal human growth and development. Iodine Deficiency Disorders (IDD) are an important public health problem in India. There has been no data on the prevalence of IDD from the Kottayam district, India and hence, the present pilot study was conducted in the year 1999 to assess whether iodine deficiency existed in the district or not and to estimate the iodine content of salt consumed by the population. A total of 1872 children in the age group of 6-12 years were included in the study and were clinically examined. On the spot urine samples were collected from 251 children. A total of 420 salt samples were collected randomly from the families of the children. The total goitre prevalence was found to be 7.05% in the subjects studied. It was found that the percentage of children with urinary iodine excretions of < 2, 2- < 5, 5-9 and 10 microg/dL and above were 6.4%, 6.0%, 20.7%, and 66.9%, respectively. Assessment of the iodine content of salt by the iodometric titration method revealed that 60.6% of the children were consuming salt with an iodine content of 15 p.p.m. and more, which was the stipulated level of salt iodisation. The findings of the present study indicated that the population is in a transitional phase from iodine deficient, as revealed by total goitre rate, to iodine sufficient nutriture, as revealed by the median urinary iodine excretion level of 17.5 microg/dL.


Subject(s)
Goiter/epidemiology , Iodine/deficiency , Iodine/urine , Child , Humans , India , Pilot Projects , Sodium Chloride/analysis
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