ABSTRACT
Chemical investigation of the n-butanol extract from the methanol extract of the root bark of Artocarpus nobilis furnished four new prenylated flavonoids together with artonin E 2'-methylether (4), isoartonin E 2'-methylether (5), dihydroisoartonin E 2'-methylether (6), artonin V 2'-methylether (7), artobiloxanthone (1), artonin E (2) and cycloartobiloxanthone (3). All these compounds showed strong radical scavenging properties towards DPPH radical.
Subject(s)
Antioxidants/isolation & purification , Artocarpus/chemistry , Free Radical Scavengers/isolation & purification , Plant Extracts/isolation & purification , Antioxidants/chemistry , Antioxidants/pharmacology , Biphenyl Compounds , Flavonoids/chemistry , Flavonoids/isolation & purification , Flavonoids/pharmacology , Free Radical Scavengers/chemistry , Free Radical Scavengers/pharmacology , Hydrazines , Molecular Structure , Picrates , Plant Bark , Plant Extracts/chemistry , Plant Extracts/pharmacology , Plant RootsABSTRACT
Chemical investigation of the dichloromethane extract of the leaves of Syzygium jambos furnished three dihydrochalcones, phloretin 4'-O-methyl ether (2',6'-dihydroxy-4'-methoxydihydrochalcone) (1), myrigalone G (2',6'-dihydroxy-4'-methoxy-3'-methyldihydrochalcone) (2), and myrigalone B (2',6'-dihydroxy-4'-methoxy-3,5'-dimethyldihydrochalcone) (3) with radical scavenging properties towards the DPPH radical by spectrophotometric method.
Subject(s)
Chalcones/chemistry , Chalcones/pharmacology , Free Radical Scavengers/chemistry , Free Radical Scavengers/pharmacology , Phloretin/analogs & derivatives , Syzygium/chemistry , Molecular Structure , Phloretin/chemistry , Phloretin/pharmacology , Plant Leaves/chemistryABSTRACT
Chemical investigation of polar fractions of the methanol extract of the fruits of Diploclisia glaucescens of the family Menispermaceae furnished two new phenyl glycosides, 4-(2-nitroethyl)phenyl-beta-D-xylopyranosyl-(l approximately 6)-beta-D-glucopyranoside, and 4-cyanophenyl-beta-D-xylopyranosyl-(l approximately 6)-beta-D-glucopyranoside.
Subject(s)
Glycosides/pharmacology , Menispermaceae/chemistry , Carbohydrate Sequence , Chromatography, High Pressure Liquid , Chromatography, Thin Layer , Fruit/chemistry , Magnetic Resonance Spectroscopy , Molecular Sequence Data , Plant Extracts/chemistry , Spectrophotometry, Infrared , Spectrophotometry, UltravioletABSTRACT
Chemical investigation of methanol extract of the fruits of Diploclisia glaucescens furnished 3-O-beta-D-glucopyranosyl-20-hydroxyecdysone, 3-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl]serjanic acid 28-O-beta-D-glucopyranosyl ester and 3-O-[beta-xylopyranosyl(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl]serjanic acid 28-O-beta-D-glucopyranosyl ester. The latter saponin was found to be a new natural product while the other two are reported for the first time from the family Menispermaceae.
Subject(s)
Menispermaceae/chemistry , Saponins/chemistry , Saponins/isolation & purification , Fruit/chemistry , Plant Extracts/analysisABSTRACT
Chemical investigation of n-butanol extract from the methanol extract of leaves of Grewia damine furnished lupeol, sitosterol beta-D-glucoside, flavone C-glycosides vitexin, isovitexin where as the same extracts from the leaves of Filicium decipiens furnished sitosterol beta-D-glucoside, 3-O-beta-D-glucopyranosyl kaempferol, 3-O-beta-D-glucopyranosylquercetin and 3-O-alpha-L-rhamnopyranosyl(1--> 2)-beta-D-glucopyranosylkaempferol.
Subject(s)
Glycosides/chemistry , Grewia , Phytotherapy , Plant Extracts/chemistry , Sapindaceae , Humans , Magnetic Resonance Spectroscopy , Plant LeavesABSTRACT
Antifungal activity-guided fractionation of the n-butanol extract from the methanol extract of the stem bark of Artocarpus nobilis furnished two stilbene derivatives (E)-4-isopentenyl-3,5,2',4'-tetrahydroxystilbene and (E)-4-(3-methyl-E-but-1-enyl)-3,5,2',4'-tetrahydroxystilbene. Both compounds showed strong antifungal activity against Cladosporium cladosporioides and high radical scavenging activity towards the DPPH radical in TLC bio-autography method.
Subject(s)
Antifungal Agents/pharmacology , Artocarpus , Cladosporium/drug effects , Free Radical Scavengers/pharmacology , Phytotherapy , Plant Extracts/pharmacology , Antifungal Agents/administration & dosage , Antifungal Agents/therapeutic use , Biphenyl Compounds , Free Radical Scavengers/administration & dosage , Free Radical Scavengers/therapeutic use , Humans , Microbial Sensitivity Tests , Picrates/chemistry , Plant Bark , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use , Stilbenes/administration & dosage , Stilbenes/pharmacology , Stilbenes/therapeutic useABSTRACT
Nineteen solvent extracts from seven Sri Lankan plants were examined for nematicidal activity against the root knot nematode Meloidogyne incognita. Extracts of Allophyhu cobbe, Lepisanthes tetraphylla (Sapindaceae), Sarcococca zeylanica (Buxaceae) and Hedyotis lawsoniae (Rubiaceae) have shown significant nematicidal activity.
Subject(s)
Anthelmintics/pharmacology , Plant Extracts/pharmacology , Plants/chemistry , Tylenchoidea/drug effects , Animals , Anthelmintics/chemistry , Larva/drug effects , Plant Extracts/chemistry , Sri LankaABSTRACT
Twenty nine solvent extracts from twenty Sri Lankan plants were examined for antifeedant activity against the fourth instar larvae of Mexican bean beetle, Epilachna varivestis Muls., Coccinellidae. Extracts of Sarcococca brevifolia (Buxaceae), Strychnus nux vomica (Loganiaceae), Diploclisia glaucescens, Coscinium fenestratum (Menispermaceae), Syzygium caryophyllatum (Myrtaceae), Pittosporium zeylanicum (Pittosporaceae), Lasianthus gardneri (Rubiaceae), Ferronia limonia (Rutaceae) and Allophylus cobbe (Sapindaceae) have shown strong antifeedant activity.
Subject(s)
Coleoptera , Insecticides , Magnoliopsida/chemistry , Plant Extracts , Animals , Buxaceae/chemistry , Fabaceae/chemistry , Feeding Behavior/drug effects , Insecticides/isolation & purification , Loganiaceae/chemistry , Myrtaceae/chemistry , Rubiaceae/chemistry , Rutaceae/chemistry , Sapindaceae/chemistry , Sri LankaABSTRACT
Complete 1H and 13C NMR assignments are described for two known oleanane glycosides, 3-O-beta-D-glucopyranosyl(1-->3)-beta-D-glucopyranosyl-28-O-beta-D-glucopyranosyloleanolic acid and 3-O-beta-D-xylopyranosyl(1-->2)-beta-D-glucopyranosyl-28-O-beta-D-glucopyranosyl oleanolic acid isolated from the methanol extract of the leaves of Diploclisia glaucescens.
Subject(s)
Glycosides/isolation & purification , Menispermaceae/chemistry , Plant Leaves/chemistry , Triterpenes/chemistry , Glycosides/chemistry , Medicine, Traditional , Oleanolic Acid/analogs & derivatives , Sri LankaABSTRACT
Ninety solvent extracts (n-hexane, dichloromethane and methanol) obtained from the leaves, bark and stem of 13 Sri Lankan Rubiaceae and two Sri Lankan Meliaceae plants have been screened for antibacterial and antifungal activities. Morinda tinctoria, Mussaenda frondosa, Psychotria gardneri and Psychotria stenophylla displayed the widest spectrum of antibacterial activity.
