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1.
Pan Afr Med J ; 43: 196, 2022.
Article in French | MEDLINE | ID: mdl-36942131

ABSTRACT

Idiopathic granulomatous mastitis (IMD) is a chronic benign inflammatory disease of the breast which can mimic breast cancer. It is more common in young women of childbearing age and poses a challenge in diagnosis of inflammatory breast tumor. We report the case of a 26-year-old female patient who presented with inflammatory breast. Clinical examination showed apyretic patient with edematized and painless irregular smooth mass in the left breast measuring 4 cm surmounted by crusts and multiples fistulizing scars discharging pus by applying pressure, with mobile ipsilateral axillary adenopathy. The remainder of the physical examination showed inflammatory erythematous patches on both legs. A mammogram plus breast ultrasound was performed followed by biopsy that objectified fibrous mastopathy. Lumpectomy was performed due to the persistence of symptoms. Anatomopathological examination objectified granulomatous mastitis. Etiological research didn't identify a clear cause. Corticotherapy associated with antibiotic therapy was started with complete regression of symptoms after two months.


Subject(s)
Breast Diseases , Breast Neoplasms , Erythema Nodosum , Granulomatous Mastitis , Female , Humans , Adult , Granulomatous Mastitis/complications , Granulomatous Mastitis/diagnosis , Erythema Nodosum/etiology , Erythema Nodosum/complications , Breast/pathology , Breast Neoplasms/diagnosis
2.
Pan Afr Med J ; 37: 17, 2020.
Article in English | MEDLINE | ID: mdl-33062119

ABSTRACT

With the increased use and quality of ultrasound in pregnancy, adnexal masses are being encountered with greater frequency. Most of the time such masses are asymptomatic. It can be discovered in an emergency. Surgical intervention may cause risks to the mother and her fetus, while observation without intervention may also lead to unfavorable complications, such as ovarian torsion or the development of a tumor. Therefore, the management requires a balance between the maternal and fetal risks. We report two cases of torsion of adnexal masses during pregnancy, and we provide a brief literature review on the management and prognosis of this condition in pregnancy.


Subject(s)
Adnexal Diseases/diagnosis , Pregnancy Complications/diagnosis , Torsion Abnormality/diagnosis , Adnexal Diseases/pathology , Adnexal Diseases/therapy , Adolescent , Adult , Female , Humans , Pregnancy , Pregnancy Complications/pathology , Pregnancy Complications/therapy , Pregnancy Outcome , Prognosis , Torsion Abnormality/pathology , Torsion Abnormality/therapy
3.
J Med Case Rep ; 14(1): 198, 2020 Oct 22.
Article in English | MEDLINE | ID: mdl-33087174

ABSTRACT

BACKGROUND: During pregnancy, the discovery of adnexal masses remains frequent. Such masses are mostly benign. Ovarian endometrioma is a rare etiology. The diagnosis may be difficult in some situations, such as decidualization. It may be asymptomatic or result in complications for which magnetic resonance imaging is needed. CASE PRESENTATION: We describe an unusual case of decidualization of an ovarian endometrioma complicated by a sigmoid fistula during a 7-week, 1-day pregnancy in a Arabic patient aged 38 years who developed acute pelvic pain with fever. She had a medical history of unexplored secondary dysmenorrhea. The diagnosis was suspected on the basis of magnetic resonance imaging findings. The management was based on surgery, during which exploration revealed a mass at the expense of the left ovary being very adherent and fistulized to the sigmoid. We performed adnexectomy followed by digestive ostomy. The result of pathological study with immunohistochemistry led to a diagnosis of decidualization of an ovarian endometrioma altered by infection. CONCLUSION: Decidualization of an ovarian endometrioma can lead sometimes to unexpected complications. The decision to provide surgery must be made with caution without delaying treatment in the event of a deep suspicion of malignancy and/or complication. The particular and exceptional complication discovered in our patient is the fistulization to the sigmoid.


Subject(s)
Adnexal Diseases , Endometriosis , Fistula , Adult , Dysmenorrhea , Endometriosis/complications , Endometriosis/diagnostic imaging , Endometriosis/surgery , Female , Humans , Pelvic Pain , Pregnancy
4.
Pan Afr Med J ; 33: 279, 2019.
Article in French | MEDLINE | ID: mdl-31692819

ABSTRACT

Multicystic dysplastic kidney (MCDK) is the most common Congenital Abnormalities of Kidney and Urinary Tract (CAKUT) in clinical practice. Its etiology and pathogenesis are still controversial and obstruction is a generally accepted causative assumption. Obstetric ultrasound is the gold standard for prenatal diagnosis and for the detection of other associated malformations. Prenatal management is based on ultrasound monitoring of pregnancy, of the disease, of the occurrence of other anomalies and of the amount of amniotic fluid. This study aims to report our experience in the Department of Gynecology-Obstetrics 2 at the University Hospital Hassan II-Fez in order to clarify the epidemiology of MCDK, highlight the role of obstetric ultrasound in positive and etiological diagnosis while describing the various sonographic appearances. It is essential to schedule for screening tests during pregnancy in order to assess the evolution of the disease diagnosed in the prenatal period, to implement a strategy in postpartum care and to establish a prognosis.


Subject(s)
Amniotic Fluid/metabolism , Multicystic Dysplastic Kidney/diagnostic imaging , Ultrasonography, Prenatal/methods , Abnormalities, Multiple/diagnostic imaging , Female , Humans , Infant, Newborn , Male , Pregnancy , Retrospective Studies
5.
Pan Afr Med J ; 32: 116, 2019.
Article in French | MEDLINE | ID: mdl-31223406

ABSTRACT

Amniotic band syndrome (ABS) comprises of a spectrum of complex congenital malformations mainly interesting the limbs, but even the craniofacial region and the thoracoabdominal axis. There are two major opposing pathophysiological theories: premature rupture of the amniotic sac (exogenous growth theory) would result in the formation of fibrous bands which would lead to strangulation, thus causing the observed abnormalities; the endogenous theory holds that this is a syndrome of vascular origin and that the bands have no causative role. Prognosis depends on the severity of malformations. We here report two cases of lethal malformations in order to discuss the challenges in the diagnosis and treatment of amniotic band syndrome. This study mainly aims to highlight the role of prenatal diagnosis in the therapeutic management of this embryo-fetopathy.


Subject(s)
Amniotic Band Syndrome/diagnosis , Prenatal Diagnosis/methods , Adult , Amniotic Band Syndrome/physiopathology , Female , Humans , Pregnancy , Prognosis
6.
Pan Afr Med J ; 31: 227, 2018.
Article in French | MEDLINE | ID: mdl-31447985

ABSTRACT

Cesarean-scar pregnancy is a rare form of the ectopic pregnancy which can be life-threatening or threaten patient's functional prognosis due to hemorrhage or early uterine rupture. We report the case of a 23-year old patient with ectopic pregnancy, gravida 3, para 2, with bi-scarred uterus who was diagnosed with cesarean-scar pregnancy due to metrorrhagias at 7 weeks of amenorrhea. Transvaginal ultrasound allowed early diagnosis and treatment was based on conservative therapy. This study and literature review aim to highlight the diagnostic and therapeutic features of this rare disorder whose knowledge can improve prognosis.


Subject(s)
Cesarean Section/adverse effects , Cicatrix/pathology , Pregnancy, Ectopic/diagnosis , Uterus/pathology , Cicatrix/etiology , Female , Humans , Pregnancy , Pregnancy, Ectopic/pathology , Young Adult
7.
Pan Afr Med J ; 27: 263, 2017.
Article in French | MEDLINE | ID: mdl-29187932

ABSTRACT

Ovarian teratomas are tumors resulting from pluripotent germ cells. We here describe 3 different types of teratomas: mature, immature and monodermal teratomas. Immature teratoma accounts for less than 1% of ovarian cancers and mainly affects young subjects. We report the case of a 25 year female patient, admitted with abdomino pelvic mass. She underwent ultrasound and a pelvic CT scan followed by conservative treatment based on left annexectomy associated with multiple biopsies. Anatomopathological examination showed immature ovarian teratoma. Patient's treatment was supplemented by a hysterectomy with lumbo-aortic curage and omentectomy. We highlight, through this study and review of the literature, the predisposing factors for this type of rare and severe tumor and the radiological features suggesting these rare histological types of ovarian tumors, in order to improve the prognosis and multidisciplinary management of patients.


Subject(s)
Ovarian Neoplasms/diagnostic imaging , Teratoma/diagnostic imaging , Adult , Female , Humans , Hysterectomy/methods , Ovarian Neoplasms/pathology , Ovarian Neoplasms/surgery , Prognosis , Radiography , Teratoma/pathology , Teratoma/surgery , Tomography, X-Ray Computed , Ultrasonography
8.
Pan Afr Med J ; 28: 148, 2017.
Article in French | MEDLINE | ID: mdl-29541296

ABSTRACT

We report the case of Ms. A.A, a primiparous woman aged 21 years presenting (4 months after delivery) with an increase in left breast volume occurred 1 week after delivery associated with fever. The patient was put on amoxicillin, protected by suspending breast-feeding for several weeks without improvement. Clinical examination showed febrile patient with a temperature of 39°, an increase in left breast volume, inflammatory signs especially at the level of internal quadrants (A). Palpation showed a painful, hot collection adherent to the skin, measuring 16 cm, at the level of the internal quadrants, invading the external quadrants, without axillary adenopathies, suggesting breast abscess. Ultrasound (B) showed voluminous solidocystic predominantly liquid echogenic mass with thick walls and buds up to 46 mm, classified as ACR4. Puncture biopsy collected grayish green liquid, sent for bacteriological examination; antibiotic therapy with quinolones was started. Follow up of patient, after 3 days, showed reduction of the inflammatory signs and bacteriological examination of the liquid found no germ. After 15 days of antibiotic therapy, the inflammatory signs had disappeared and the volume of the mass had reduced enough, hence the indication for cystectomy. Cystectomy with simple enucleation was performed (C); surprisingly, the histological examination showed cystic fibroadenoma (D).


Subject(s)
Breast Neoplasms/diagnosis , Fibroadenoma/diagnosis , Mastitis/diagnosis , Anti-Bacterial Agents/therapeutic use , Biopsy, Needle , Breast Neoplasms/pathology , Breast Neoplasms/surgery , Female , Fibroadenoma/pathology , Fibroadenoma/surgery , Fibrocystic Breast Disease/diagnosis , Fibrocystic Breast Disease/pathology , Fibrocystic Breast Disease/surgery , Follow-Up Studies , Humans , Mastitis/drug therapy , Postpartum Period , Young Adult
14.
J Med Case Rep ; 8: 465, 2014 Dec 26.
Article in English | MEDLINE | ID: mdl-25541096

ABSTRACT

INTRODUCTION: A granular cell tumor involving the breast parenchyma was first described by Abrikossoff in 1931. Localization of this lesion to the breast is very rare, accounting for between 5% and 15% of all granular cell tumor cases. We present this case because of the rarity of this tumor. It is frequently confused with breast carcinoma on clinical and radiological examination, and its diagnosis can therefore be challenging for clinicians, radiologists and pathologists. CASE PRESENTATION: We report the case of a 32-year-old Moroccan woman who presented with a palpable mass in her right breast. Mammography and ultrasound examination revealed a heterogeneous, irregular and poorly limited mass, located at the union of the outer quadrants of her right breast. The mass was in contact with her latissimus dorsi and suspicious for malignancy. A histological examination combined with immunohistochemical study revealed it to be a granular cell tumor. CONCLUSION: Although a granular cell tumor of the breast is a rare breast neoplasm, it should be considered in the differential diagnosis of benign and malignant lesions. Pathologists should bear in mind a granular cell tumor when examining material containing cells with abundant granular cytoplasm to avoid misdiagnosing breast carcinoma, which could lead to unnecessary surgery.


Subject(s)
Breast Neoplasms/pathology , Granular Cell Tumor/pathology , Mammography , Ultrasonography, Mammary , Adult , Breast Neoplasms/surgery , Diagnosis, Differential , Female , Granular Cell Tumor/surgery , Humans , Immunohistochemistry , Treatment Outcome , Unnecessary Procedures
17.
J Med Case Rep ; 8: 241, 2014 Jul 01.
Article in English | MEDLINE | ID: mdl-24986146

ABSTRACT

INTRODUCTION: Embryonal rhabdomyosarcoma of the female genital tract is rare in the cervix. It has been mainly discussed in the context of individual case studies. It tends to occur in children and young women. Treatment ranges from radical surgery to conservative surgery, followed by chemotherapy. CASE PRESENTATION: A 16-year-old Moroccan adolescent girl presented to our center with a protruding mass from her vaginal introitus, as a polyp of 6cm. An examination revealed a polyp within her vagina, thought to be arising from her cervix and a polypectomy was performed. Microscopic findings are consistent with an embryonal rhabdomyosarcoma (botryoide type). A computed tomography of her thorax, abdomen and pelvis were performed and residual disease was found as a mass located at her cervix, which measured approximately 4.5cm in its widest dimensions, without evidence of metastatic disease. Due to the fact that she is young, after discussions in a multidisciplinary meeting, she was subsequently treated with four cycles of multi-agent chemotherapy. Two cycles of chemotherapy and radiotherapy were administered due to the lack of response, but she presented vaginal bleeding with persistence of the same mass in computed tomography. Hence a total interadnexal hysterectomy was made. A histologic examination found residual embryonal rhabdomyosarcoma (botryoide type) located in all her cervix and she is currently under chemotherapy. CONCLUSIONS: The presence of a cervical polyp in an adolescent is a gynecologic oddity and must necessarily be examined histologically because it might be a rhabdomyosarcoma. This is extremely important because diagnosis at an early stage of the disease is a highly favorable prognostic factor that allows "fertility-sparing surgery" for these young patients.


Subject(s)
Polyps/pathology , Rhabdomyosarcoma, Embryonal/pathology , Uterine Cervical Neoplasms/pathology , Adolescent , Female , Humans
18.
J Med Case Rep ; 8: 203, 2014 Jun 18.
Article in English | MEDLINE | ID: mdl-24946809

ABSTRACT

INTRODUCTION: Vulvar lipoma is a rare tumor localization and only a few cases have been reported. The clinical characteristics of vulvar lipoma are well known. However, it is important to distinguish lipomas from liposarcomas. We report a case of vulvar lipoma and discuss its clinical features, including diagnostic aspects, with emphasis on histopathological evaluation of all excised lesions. We also report and discuss patient management and treatment outcomes. CASE PRESENTATION: We report the case of a 27-year-old Moroccan woman. Our patient presented with a painless and slow-growing right vulvar mass that had evolved over one year, which had suddenly become uncomfortable when walking. A physical examination revealed a single soft and pasty mass in her left labium majus, which could be mobilized under her skin towards her mons pubis. The largest dimension of the mass measured 6cm. Magnetic resonance imaging showed a homogenous hyperintense mass with a well-defined contour in her left labium majus; a fat-suppressed magnetic resonance image demonstrated a marked signal intensity decrease. The mass was completely removed surgically. A histological examination revealed a circumscribed benign tumor composed of mature adipocytes, confirming the diagnosis of vulvar lipoma. CONCLUSION: Vulvar lipomas must be differentiated from liposarcomas, which demonstrate very similar clinical and imaging profiles. The final diagnosis should be based on histopathological evaluation. A precise diagnosis should allow for appropriate surgical treatment.


Subject(s)
Lipoma/diagnosis , Vulvar Neoplasms/diagnosis , Adult , Female , Humans , Lipoma/pathology , Lipoma/surgery , Magnetic Resonance Imaging , Vulva/pathology , Vulva/surgery , Vulvar Neoplasms/pathology , Vulvar Neoplasms/surgery
19.
J Med Case Rep ; 8: 207, 2014 Jun 18.
Article in English | MEDLINE | ID: mdl-24943121

ABSTRACT

INTRODUCTION: Pregnancy-related compressive myelopathy secondary to vertebral hemangioma is a rare occurrence and its treatment antepartum is rare. CASE PRESENTATION: A 19-year-old North African woman in her 38th week of pregnancy presented with paraplegia that progressed within 2 days after a rapidly progressive weakness of her lower limbs. Magnetic resonance imaging studies showed compression of her spinal cord in front of the fourth thoracic vertebra for suspected tuberculous spondylitis. A Caesarean section was done followed by corpectomy with a bone graft because we intraoperatively discovered a vertebral hemangioma. Pathology showed an aggressive hemangioma. CONCLUSION: At any term of pregnancy, extensive neurological involvement which is rapidly progressive due to compression should be considered for immediate decompression.


Subject(s)
Hemangioma/diagnosis , Pregnancy Complications, Neoplastic/diagnosis , Spinal Cord Compression/diagnosis , Spinal Neoplasms/diagnosis , Thoracic Vertebrae/pathology , Cesarean Section , Decompression, Surgical , Female , Hemangioma/complications , Hemangioma/surgery , Humans , Magnetic Resonance Imaging , Pregnancy , Pregnancy Complications, Neoplastic/surgery , Pregnancy Trimester, Third , Spinal Cord Compression/etiology , Spinal Cord Compression/surgery , Spinal Neoplasms/complications , Spinal Neoplasms/surgery , Thoracic Vertebrae/surgery , Young Adult
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