ABSTRACT
The acetylation of aryl ethers using acetic anhydride in the presence of zeolites under modest conditions in a solvent-free system gave the corresponding para-acetylated products in high yields. The zeolite can be recovered, regenerated and reused to give almost the same yield as that given when fresh zeolite is used.
ABSTRACT
Acylation of anisole with 2-phenylbutanoic acid derivatives, over zeolite catalysts, gives the corresponding 4-acyl derivatives with high regioselectivity. In an analogous way, 2,3-dihydrobenzofuran reacts with acid anhydrides or chlorides in the presence of catalytic quantities of zeolites to give the corresponding 5-acyl-2,3-dihydrobenzofurans. The zeolite can be recovered, regenerated and used again to give almost the same yield as with fresh zeolite. The reaction has been applied to the synthesis of ethyl (2,3-dihydrobenzofuran-5-yl)glyoxylate.