ABSTRACT
INTRODUCTION: Myotonic dystrophy is one of the most common autosomal dominant inherited muscular diseases. In both subtypes, not only the musculoskeletal system but other organs are also affected as a result of mis-splicing of several messenger RNAs leading to the production of dysfunctional proteins. Cataract, reduced pulmonary capacity, rhythm disorders, glucose intolerance, dyslipidaemia, endocrinopathies and cognitive impairment are also obtained in patients with myotonic dystrophy. OBJECTIVE: We aimed to assess the risk factors of ischaemic stroke in our patients. METHOD: After a detailed review of the patients' medical history, laboratory and clinical tests and a carotid ultrasound examination were performed. RESULTS: We found atherogenic dyslipidaemia, high risk of cardiogenicembolism, and normal carotid artery intimal media thickness. DISCUSSION: Our result can suggest the role of atrial fibrillation and other supraventricular rhythm disorders as important risk factors for ischemic stroke in patients with myotonic dystrophy. CONCLUSION: During the longitudinal follow-up of the patient population suffering from dystrophia myotonica type 1, special attention must also be paid to cardiology care. Orv Hetil. 2022; 163(49): 1962-1966.
