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1.
Spine (Phila Pa 1976) ; 20(1): 80-9, 1995 Jan 01.
Article in English | MEDLINE | ID: mdl-7709284

ABSTRACT

STUDY DESIGN: This study analyzed the clinical history, physical examination, diagnostic studies, and operative and histologic findings in 19 patients with lumbar intraspinal synovial and ganglion facet cysts evaluated and treated over a 10-year period. OBJECTIVES: The results were correlated to provide a greater understanding of lumbar facet cysts and rationale for conservative or surgical treatments. SUMMARY OF BACKGROUND DATA: The 19 patients included 13 women and 6 men ranging in age from 38 to 79 years. 84.4% of the patients presented with radicular pain. 26.3% had significant motor deficit. 68.4% of the facet cysts were found at L4-L5, 21.1% at L5-S1, 5.2% at L1-L2, and 5.2% at L2-L3. METHODS: The clinical history and findings on physical examination, standard radiography, myelography, computed tomography-myelography, facet arthrography, post-facet arthrograph computed tomography, magnetic resonance imaging with and without contrast, and computed tomography scans were reviewed. RESULTS: Bilobed cysts were found on both dorsal and ventral aspects of the involved facet joints within and outside of the spinal canal on facet arthrography, computed tomography, magnetic resonance imaging, and at the time of surgery in more than 60% of the patients. Significant facet degeneration was found in 75% of standard radiographs, and on all of the magnetic resonance imaging and computed tomography scans. In six patients, symptoms improved with rest, medication, and bracing. Epidural corticosteroid injections provided short-term relief in three out of four patients. Facet corticosteroid injections provided good relief in one, partial relief in one, and no relief in one patient. Surgical decompression in eight patients resulted in three excellent, four good, and one fair outcome. CONCLUSIONS: Most of the lumbar intraspinal facet cysts were associated with significantly degenerated facet joints. Patients with intraspinal facet cysts may respond to conservative treatments if there is no significant neurologic deficit. Surgical decompression and removal of large facet cysts usually are successful in relieving symptoms.


Subject(s)
Cysts/pathology , Ganglia, Spinal/pathology , Lumbosacral Region/pathology , Synovial Cyst/pathology , Adrenal Cortex Hormones/therapeutic use , Adult , Aged , Cysts/diagnostic imaging , Cysts/drug therapy , Cysts/surgery , Female , Follow-Up Studies , Ganglia, Spinal/diagnostic imaging , Ganglia, Spinal/surgery , Humans , Lumbosacral Region/diagnostic imaging , Lumbosacral Region/surgery , Magnetic Resonance Imaging , Male , Middle Aged , Retrospective Studies , Synovial Cyst/diagnostic imaging , Synovial Cyst/drug therapy , Synovial Cyst/surgery , Tomography, X-Ray Computed
2.
Neurosurgery ; 35(5): 947-50; discussion 950-1, 1994 Nov.
Article in English | MEDLINE | ID: mdl-7838347

ABSTRACT

We report a case of pleomorphic xanthoastrocytoma occurring in the midline cerebellum of a 48-year-old woman. Radiological, histological, immunohistochemical, and flow cytometric findings are discussed. Pleomorphic xanthoastrocytoma typically occurs in the superficial cerebral hemispheres of young patients. To our knowledge, this is the first report of the occurrence of this neoplasm in the cerebellum. The English literature is reviewed with regard to the clinicopathological features of this uncommon form of astrocytoma.


Subject(s)
Astrocytoma/surgery , Cerebellar Neoplasms/surgery , Astrocytoma/diagnosis , Astrocytoma/pathology , Biomarkers, Tumor/analysis , Cell Division/physiology , Cerebellar Neoplasms/diagnosis , Cerebellar Neoplasms/pathology , Cerebellum/pathology , Cerebellum/surgery , Craniotomy , Female , Flow Cytometry , Glial Fibrillary Acidic Protein/analysis , Humans , Immunoenzyme Techniques , Magnetic Resonance Imaging , Middle Aged , S100 Proteins/analysis , Vimentin/analysis
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