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Clin Otolaryngol ; 42(3): 673-680, 2017 Jun.
Article in English | MEDLINE | ID: mdl-27882653

ABSTRACT

OBJECTIVES: To study the development of synkinesis in Bell's palsy. Frequency, severity, gender aspects and predictors were analysed. DESIGN: Data from the randomised controlled Scandinavian Bell's palsy trial including 829 patients. MAIN OUTCOME MEASURES: Frequency and severity of synkinesis at 12 months were the main outcome measures. Mean Sunnybrook synkinesis scores, voluntary movement scores and composite scores between 6 and 12 months were compared. RESULTS: In 743 patients with a 12-month follow-up, synkinesis frequency was 21.3%. There was no gender difference. Synkinesis was moderate to severe in 6.6% of patients. Those with synkinesis at 6 months had a synkinesis score of 4.1 (±2.8 sd), which increased to 4.7 (±3.2) (P = 0.047) at 12 months (n = 93). Sunnybrook composite score at 1 month was the best predictor for synkinesis development with receiver operating characteristics and area under the curve (AUC) 0.87. Risk for synkinesis increased with a lower Sunnybrook composite score. Furthermore, at 1 month, symmetry of voluntary movement had higher predictive value for synkinesis than resting symmetry with AUC 0.87 and 0.77, respectively. Gentle eye closure and open-mouth smile were the only independent significant predictive items (AUC 0.86). CONCLUSIONS: Moderate-to-severe synkinesis was present in 6.6% of patients. The mean synkinesis score increased between 6 and 12 months, and outcome should therefore be evaluated after at least 12 months. Sunnybrook composite score and symmetry of voluntary movement at 1 month were good predictors for synkinesis.


Subject(s)
Acyclovir/analogs & derivatives , Bell Palsy/complications , Prednisolone/administration & dosage , Synkinesis/etiology , Valine/analogs & derivatives , Acyclovir/administration & dosage , Adolescent , Adult , Aged , Antiviral Agents/administration & dosage , Bell Palsy/diagnosis , Bell Palsy/drug therapy , Dose-Response Relationship, Drug , Double-Blind Method , Drug Therapy, Combination , Female , Follow-Up Studies , Glucocorticoids/administration & dosage , Humans , Male , Middle Aged , Synkinesis/diagnosis , Synkinesis/drug therapy , Time Factors , Treatment Outcome , Valacyclovir , Valine/administration & dosage , Young Adult
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