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1.
Trop Gastroenterol ; 27(1): 50-1, 2006.
Article in English | MEDLINE | ID: mdl-16910064

ABSTRACT

This is a case report of a 29 year old woman who presented with painless and progressive obstructive jaundice. Imaging investigations of the abdomen revealed a tumour of the common bile duct. She was treated by complete excision of the bile duct and hepaticojejunostomy. The histopathology report of the tumour read as benign schwannoma.


Subject(s)
Common Bile Duct Neoplasms/pathology , Jaundice, Obstructive/etiology , Neurilemmoma/pathology , Adult , Common Bile Duct Neoplasms/complications , Common Bile Duct Neoplasms/surgery , Female , Humans , Neurilemmoma/complications , Neurilemmoma/surgery
2.
Colorectal Dis ; 8(4): 342-6, 2006 May.
Article in English | MEDLINE | ID: mdl-16630241

ABSTRACT

BACKGROUND: Radiation proctitis is a common complication following radiation therapy for pelvic malignancies. This is associated with significant morbidity which adversely affects the quality of life. Local application of formalin has been used effectively in the treatment of radiation proctitis. METHODOLOGY: Thirty patients with haemorrhagic radiation proctitis who underwent endoluminal application of 4% formalin between January 1998 to October 2002 were followed up prospectively to assess the efficacy of the treatment. RESULTS: The follow up ranged from 5 to 36 months (mean 18.1 months). Nineteen (63.3%) patients had complete response to formalin application while 7 (23.3%) patients had partial response. There were 4 (13.3%) failures. No procedure related complication was observed. CONCLUSION: Local application of formalin is a simple, safe, inexpensive and fairly effective outpatient treatment modality for chronic radiation proctitis.


Subject(s)
Formaldehyde/administration & dosage , Gastrointestinal Hemorrhage/drug therapy , Hemostatics/administration & dosage , Proctitis/drug therapy , Radiation Injuries/drug therapy , Radiotherapy/adverse effects , Adult , Aged , Colonoscopy , Female , Follow-Up Studies , Gastrointestinal Hemorrhage/etiology , Humans , Middle Aged , Proctitis/etiology , Prospective Studies , Radiation Injuries/etiology , Treatment Outcome
3.
HPB (Oxford) ; 8(4): 299-305, 2006.
Article in English | MEDLINE | ID: mdl-18333140

ABSTRACT

BACKGROUND: Choledochal cyst, a common surgical problem of childhood, can have a delayed presentation in adults. The clinical course in adults differs from that in children because of a higher incidence of associated hepatobiliary pathology. METHODS: The clinical data of 57 adults with choledochal cyst managed in a general surgical unit between January 1988 and March 2003 were analysed. RESULTS: The male:female ratio was 1:1.38 and the mean age was 34.5 years; 71.9% of the cysts belonged to Todani type I, 26.3% to type IV and 1.8% to type V. Abdominal pain and recurrent cholangitis were the commonest presentations followed by acute pancreatitis, palpable mass and bronchobiliary fistula. Anomalous pancreaticobiliary ductal junction was demonstrated in 14% of the cases. In all, 37% of the patients had undergone either wrong or suboptimal surgical procedures prior to presentation. All patients underwent complete excision of the cyst and hepaticojejunostomy. Two patients required cholangiojejunostomy and three patients required resection of the involved segments of the liver in addition. There were three anastomotic leaks and two postoperative deaths. Two anastomotic leaks resolved spontaneously while the third required surgical intervention. Forty-eight patients were available for follow-up and have remained symptom-free over a mean period of 17.6 months. CONCLUSIONS: Choledochal cyst should be considered in all patients below 40 years of age presenting with biliary colic, pancreatitis or recurrent cholangitis with associated dilatation of bile duct. Complete excision of the cyst with restoration of biliary-enteric communication by hepaticojejunostomy form the basis of ideal treatment.

5.
ANZ J Surg ; 74(8): 662-6, 2004 Aug.
Article in English | MEDLINE | ID: mdl-15315567

ABSTRACT

BACKGROUND: Mycobacterium fortuitum is an uncommon cause of soft tissue infections. Treatment is often inadequate with persistence of infection unless the aetiological agent and its antibiotic sensitivity are accurately established. METHODS: Medical records of 23 patients with chronic soft tissue infection caused by M. fortuitum over a 12-year period from 1991 to 2002 were studied. RESULTS: In 20 patients the cause was iatrogenic, following intramuscular injections (12), laparoscopy (5) and other surgical procedures (3) and in three patients discharging sinuses developed spontaneously. Patients presented with recurrent abscesses or chronic discharging sinuses that did not respond to conventional surgical drainage. The diagnosis was established by isolating M. fortuitum from the tissues in all cases. The treatment consisted of a more aggressive surgical intervention in form of excision, debridement and extensive lay open with curettage and prolonged administration of appropriate antibiotics. The organism showed maximum sensitivity to amikacin and ciprofloxacin. Healing occurred in all cases. Three patients suffered recurrences: two responded to further debridement and antibiotics and are well at 2 and 5 years, respectively. CONCLUSION: A high index of suspicion based on clinical presentation is essential to diagnose M. fortuitum as a cause of soft tissue infection. Treatment involves aggressive surgical debridement and administration of combination antibiotics based on sensitivity, which should be continued for a period that will ensure complete healing and prevent recurrence.


Subject(s)
Anti-Bacterial Agents/pharmacology , Iatrogenic Disease , Mycobacterium Infections, Nontuberculous/etiology , Mycobacterium fortuitum , Soft Tissue Infections/microbiology , Adolescent , Adult , Anti-Bacterial Agents/therapeutic use , Chronic Disease , Female , Humans , Injections, Intramuscular/adverse effects , Laparoscopy/adverse effects , Male , Microbial Sensitivity Tests , Middle Aged , Mycobacterium Infections, Nontuberculous/therapy , Mycobacterium fortuitum/drug effects , Mycobacterium fortuitum/isolation & purification , Retrospective Studies , Soft Tissue Infections/therapy
7.
Trop Gastroenterol ; 25(4): 189-90, 2004.
Article in English | MEDLINE | ID: mdl-15912984

ABSTRACT

We report the case of a paraduodenal hernia treated by reduction of the hernia and closure of the hernial orifice.


Subject(s)
Abdominal Pain/etiology , Duodenal Diseases/complications , Hernia/complications , Adult , Chronic Disease , Duodenal Diseases/diagnosis , Duodenal Diseases/surgery , Hernia/diagnosis , Herniorrhaphy , Humans , Male
8.
Trop Gastroenterol ; 24(1): 42-3, 2003.
Article in English | MEDLINE | ID: mdl-12974218

ABSTRACT

Cavernous haemangioma of the rectum is an uncommon cause of rectal bleeding. Initial diagnosis is often elusive because of lack of awareness. For accurate diagnosis, investigations such as endoscopy, plain X-ray of the abdomen, barium enema and selective angiography of the inferior mesenteric artery are required. Complete surgical excision of the haemangioma and colo-anal sleeve anastomosis is the most favoured operative procedure to eradicate the disease. We report a case of cavernous haemangioma of the rectum and discuss its salient clinical features, investigations and management.


Subject(s)
Gastrointestinal Hemorrhage/etiology , Hemangioma, Cavernous/complications , Rectal Neoplasms/complications , Adolescent , Gastrointestinal Hemorrhage/surgery , Hemangioma, Cavernous/diagnosis , Hemangioma, Cavernous/surgery , Humans , Male , Rectal Neoplasms/diagnosis , Rectal Neoplasms/surgery
12.
Ann R Coll Surg Engl ; 79(6): 410-3, 1997 Nov.
Article in English | MEDLINE | ID: mdl-9422865

ABSTRACT

The clinical features and management of 14 adults with choledochal cysts who presented to our hospital are discussed. There were 10 Todani type I, and four type IV cysts. The cysts were fusiform in all but three cases. The pancreatobiliary junction was abnormal in only two patients. Ten patients had cystolithiasis. Six patients had undergone previous biliary surgery, three of whom presented with biliary strictures. We recommend that choledochal cyst be considered as a differential diagnosis in all patients with dilated bile ducts, especially when symptoms persist after biliary surgery. In two patients who had undergone endoscopic sphincterotomy and stone clearance, and in whom the diagnosis was still in doubt after cholangiography, hepatic iminodiacetic acid (HIDA) scan confirmed the diagnosis of choledochal cyst by showing persistent biliary stagnation despite free flow of bile across the sphincter of Oddi. Complete resection of the cyst was achieved in all cases with one postoperative death. A modification of the standard surgical technique is described which makes mobilisation of the cyst easier. The need to demonstrate the pancreatobiliary ductal confluence as an aid to complete excision of the cyst is emphasised.


Subject(s)
Choledochal Cyst/surgery , Adolescent , Adult , Cholangiopancreatography, Endoscopic Retrograde , Choledochal Cyst/classification , Choledochal Cyst/diagnosis , Cholelithiasis/diagnosis , Diagnosis, Differential , Female , Follow-Up Studies , Gallbladder/diagnostic imaging , Humans , Ileum/diagnostic imaging , Imino Acids , Magnetic Resonance Imaging , Male , Middle Aged , Radionuclide Imaging , Reoperation
15.
J Assoc Physicians India ; 41(5): 266-8, 1993 May.
Article in English | MEDLINE | ID: mdl-8300455

ABSTRACT

Primary hyperaldosteronism was detected in 1% of patients evaluated for secondary hypertension in a referral hospital in Southern India. The presence of hypokalemia with inappropriate kaliuresis (24 hr. urine K > 20mEq) was an important diagnostic clue. High resolution CT scans were found to be useful for localising the tumour. Preoperatively nifedipine and spironolactone were employed to correct hypertension and hypokalemia. The same drugs were also found to be excellent for long-term control of hypertension and hypokalemia in patients who had bilateral adrenal hyperplasia and aldosteronism.


Subject(s)
Hyperaldosteronism/diagnosis , Adult , Female , Follow-Up Studies , Humans , Hyperaldosteronism/therapy , Hypokalemia/etiology , Male , Middle Aged , Nifedipine/therapeutic use , Potassium/blood , Potassium/urine , Spironolactone/therapeutic use , Tomography, X-Ray Computed
16.
Trop Gastroenterol ; 13(3): 115-8, 1992.
Article in English | MEDLINE | ID: mdl-1488798

ABSTRACT

A case of pancreatitis of filarial origin is reported for the first time. The patient presented with chronic pancreatic pain. Laparotomy revealed an inflammed pancreas and fine needle aspiration cytology confirmed pancreatitis. Imprint of a peripancreatic lymphnode revealed a microfilaria. He was successfully treated with Diethyl Carbamazine.


Subject(s)
Elephantiasis, Filarial , Pancreatitis/parasitology , Wuchereria bancrofti , Adult , Animals , Cholangiopancreatography, Endoscopic Retrograde , Humans , Lymph Nodes/parasitology , Male , Pancreatitis/diagnosis
18.
Surg Gynecol Obstet ; 161(6): 525-31, 1985 Dec.
Article in English | MEDLINE | ID: mdl-3877997

ABSTRACT

Angiodysplasia of the intestine was diagnosed by selective visceral angiography in ten of 30 patients from India with unexplained recurrent hemorrhage of the gastrointestinal tract. In contrast with the reports from the western literature, most of the instances involved the small intestine and occurred in the third decade of life.


Subject(s)
Gastrointestinal Hemorrhage/etiology , Intestinal Diseases/diagnostic imaging , Intestines/blood supply , Jejunum/blood supply , Tropical Climate , Capillaries/pathology , Capillaries/ultrastructure , Extravasation of Diagnostic and Therapeutic Materials , Gastrointestinal Hemorrhage/surgery , Humans , India , Intestinal Diseases/pathology , Intestinal Diseases/surgery , Intestinal Mucosa/pathology , Intestinal Mucosa/ultrastructure , Intestines/diagnostic imaging , Male , Radiography
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