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J Biomed Nanotechnol ; 18(4): 1028-1034, 2022 Apr 01.
Article in English | MEDLINE | ID: mdl-35854451

ABSTRACT

Two new coordination polymers, [Cu2(5-MeO-Hip)4(py)4]n (1) and [Co(5-EtO-ip)(4,4'-bipy)]n·n(MeOH) (2) (5-MeO-H2ip is 5-methoxyisophthalic acid, 5-EtO-H2ip is 5-ethoxyisophthalic acid, py is pyridine, and 4,4'-bipy is 4,4'-bipyridine), were created via solvothermal self-assembly. The thermal steadiness and photocatalytic functions of 1 and 2 were detected, and their application values in gastric cancer and the related mechanism were discussed. CCK-8 assay was used to determine the inhibitory activity toward gastric cancer cells' viability, and real-time RT-PCR was employed to examine the gastric cancer cells' Notch signaling pathway activity.


Subject(s)
Stomach Neoplasms , Humans , Polymers , Stomach Neoplasms/drug therapy
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