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1.
Artif Organs ; 29(11): 912-5, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16266306

ABSTRACT

A rotary blood pump (RP) is desirable as a small ventricular assist device (VAD). However, an RP is nonpulsatile. We tried to develop a device that attaches a pulse to the RP. We also tried to develop a pulse-generating equipment that was not air-pressure driven. The ball screw motor was considered a candidate. The application of a small-sized shape memory alloy was also attempted. An electrohydraulic system was adopted, and actuator power was connected to the diaphragm. The diaphragm was placed on the outer side of the ventricle. Most RPs that have been developed all over the world drain blood from the ventricle. The wave of a pulse should be generated if a pulse is added by the drawn part. The output assistance from the outer side of the ventricle was attempted in animal experiments, and the device operated effectively. This device can be used during implantable operation of RP. This may serve as an effective device in patients experiencing problems in peripheral circulation and in the function of internal organs.


Subject(s)
Blood Flow Velocity/physiology , Blood Pressure/physiology , Heart-Assist Devices , Pulsatile Flow/physiology , Animals , Equipment Failure Analysis , Goats , Miniaturization , Prosthesis Design , Rotation
2.
Biomed Pharmacother ; 58 Suppl 1: S145-9, 2004 Oct.
Article in English | MEDLINE | ID: mdl-15754854

ABSTRACT

The development of a rotary blood pump (RP) is desirable as it can be used as a small ventricular assistance device (VAD). However, a RP does not generate any pulse. It may be physiologically better for the patient if the RP could generate a pulse. We have attempted to develop a device that produces a pulse in the RP. Intra-aortic balloon pumping (IABP) is effective in producing a pulse. However, the IABP cannot be implanted inside the body. Therefore, an attempt was made to develop pulse-generating equipment that was not driven by air pressure. The ball screw motor was considered as a possible candidate. In the future, we plan to apply small shape memory alloys. An electrohydraulic system was adopted, and actuator power output was connected to the diaphragm. The diaphragm was placed outside the ventricle. Most RPs developed throughout the world drain blood from the ventricle. The pulse wave should be generated if a pulse is added by the part from which blood is being drawn. In this study, animal experiments were conducted and the output assistance was tested from outside the ventricle. The device operated effectively in the animal experiment. The RP can easily be equipped with this device at the time of performing the implant operation. For a patient with problems of peripheral circulation and the internal organ function, it may prove to be an effective device.


Subject(s)
Hemodynamics/physiology , Pulsatile Flow/physiology , Animal Experimentation , Animals , Equipment Design/methods , Goats , Heart-Assist Devices/trends , Humans , Japan , Multiple Organ Failure/therapy , Somatotypes/physiology
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