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2.
Opt Lett ; 48(24): 6452-6455, 2023 Dec 15.
Article in English | MEDLINE | ID: mdl-38099771

ABSTRACT

In general, atmospheric turbulence can degrade the performance of free-space optical (FSO) communication systems by coupling light from one spatial mode to other modes. In this Letter, we experimentally demonstrate a 400 Gbit/s quadrature-phase-shift-keyed (QPSK) FSO mode-division-multiplexing (MDM) coherent communication link through emulated turbulence using four Laguerre Gaussian (LG) modes with different radial and azimuthal indices (L G 10, L G 11, L G -10, and L G -11). To mitigate turbulence-induced channel cross talk and power loss, we implement an adaptive optics (AO) system at the receiver end. A Gaussian beam at a slightly different wavelength is co-propagated with the data beams as the probe beam. We use a wavefront sensor (WFS) to measure the wavefront distortion of this probe beam, and this information is used to tune a spatial light modulator (SLM) to adaptively correct the four distorted data-beam wavefronts. Using this adaptive-optics approach, the power loss and cross talk are reduced by ∼10 and ∼18 dB, respectively.

3.
Opt Express ; 29(11): 17683-17699, 2021 May 24.
Article in English | MEDLINE | ID: mdl-34154304

ABSTRACT

Cognitive visible light communication (VLC) has attracted increasing attention. By sharing underutilized VLC spectrum resources of primary users (PUs) with secondary users (SUs) opportunistically, improved spectrum utilization can be achieved without interfering with PUs. As an essential component in cognitive VLC, reliable spectrum sensing is crucial to ensure accurate cognition of PU's signal. However, due to limiting factors such as low signal-to-noise ratio (SNR) and link blocking in VLC systems, it would be difficult for a single SU to identify the status of PUs accurately and rapidly. To tackle this issue, we propose a new collaborative sensing (CS) scheme which can enhance sensing accuracy effectively by coordinating multiple SUs to participate in spectrum sensing. To evaluate the performance of the proposed CS scheme, we first develop an analytical model for the scenario of a single SU, subject to various factors such as indoor reflections and signal sampling size. Next, based on the single-SU evaluation, we further analyze the performance of the CS scheme by extending the single-SU analytical models to the multi-SU scenario. It is found that the analytical models can accurately predict the performance of the proposed CS scheme and match the results obtained by simulations. Moreover, the proposed CS scheme is effective in improving the sensing accuracy by about 40% and 10% compared with the local-sensing and the conventional CS schemes, respectively.

4.
Org Lett ; 22(11): 4366-4371, 2020 06 05.
Article in English | MEDLINE | ID: mdl-32459492

ABSTRACT

A synthesis program for structurally complex macrocycles is very challenging. Herein, we propose a biosynthesis pathway of the pyranylated cyclodepsipeptide verucopeptin to make enough supply and to diversify verucopeptin by genetic manipulation and one-step semisynthesis. The synthesis relies on the intrinsic reactivity of the interchangeable hemiketal pyrane and opened keto along with adjacent alkene. Biological evaluation of verucopeptin-oriented analogs delivers a potent AMP-activated protein kinase (AMPK) agonist, antibacterial agent, and selective NFκB modulator.


Subject(s)
AMP-Activated Protein Kinases/metabolism , Anti-Bacterial Agents/pharmacology , Depsipeptides/pharmacology , NF-kappa B/antagonists & inhibitors , Protein Kinase Inhibitors/pharmacology , Staphylococcus aureus/drug effects , Actinomadura/chemistry , Anti-Bacterial Agents/biosynthesis , Anti-Bacterial Agents/chemistry , Depsipeptides/biosynthesis , Depsipeptides/chemistry , HEK293 Cells , Humans , Microbial Sensitivity Tests , Molecular Structure , NF-kappa B/metabolism , Protein Kinase Inhibitors/chemistry , Protein Kinase Inhibitors/metabolism , Signal Transduction/drug effects
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