Amidoselenation and Amidotelluration of Alkenes using Oxygen as Terminal Oxidant.

A protocol has been established for oxygen-mediated amidoselenation and amidotelluration of alkenes under mild conditions. This method provides a simple route to a series of structurally diverse ß-amido selenides and ß-amido tellurides in moderate to high yields. The wide substrate scope, good functional group tolerance, ease of large-scale preparation and potential for product derivatization make this reaction attractive for the synthesis of nitrogen-, selenium- and tellurium-containing molecules.

Peroxodisulfate-mediated selenoamination of alkenes yielding amidoselenide-containing sulfamides and azoles.

A new protocol for C-Se and C-N bond formation by the direct difunctionalization of alkenes is reported. The protocol is operationally simple, has a wide substrate scope, and uses readily available amino sources. This reaction represents a significant addition to the limited number of intermolecular selenide difunctionalization reactions of alkenes and would find practical application in the synthesis of nitrogen- and selenium-containing molecules.