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Yao Xue Xue Bao ; 27(4): 256-60, 1992.
Article in Chinese | MEDLINE | ID: mdl-1442038

ABSTRACT

Thirteen derivatives of 6,7-methylenedioxy-1 (2H, 4H)-acridone were prepared. The structures of all the compounds synthesized were characterized by elemental analysis, IR and 1H NMR spectra. Compounds IIa, IIb, IId, IIe, IIf increased significantly the pain threshold using the hot-plate method.


Subject(s)
Acridines/chemical synthesis , Analgesics/chemical synthesis , Acridines/chemistry , Acridines/pharmacology , Analgesics/chemistry , Analgesics/pharmacology , Animals , Female , Mice , Pain/physiopathology , Sensory Thresholds/drug effects
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