ABSTRACT
Objective: To investigate the clinical characteristics of acute exacerbation of acute lung disease (AECOPD) and to provide reference for clinical diagnosis and treatment. Methods: From January 2018 to December 2018, 127 patients with AECOPD were investigated retrospectively in March 2020, including 65 cases of pneumoconiosis with AECOPD group, 62 cases of AECOPD group, 127 cases of AECOPD group, the clinical characteristics, length of stay, cost difference and the correlation between pulmonary function and blood gas were analyzed in patients with AECOPD. Results: There was no significant difference in age, height, weight, BMI, ethnicity and smoking between the two groups (P>0.05) . The percentage of Neutrophil and hs-crp in pneumoconiosis combined with AECOPD group were significantly higher than those in AECOPD group (P<0.05) . The oxygen partial pressure in pneumoconiosis combined AECOPD group was lower than that in control group (P<0.05) . VC, FVC/Pred%, FEV(1)/Pred% in pneumoconiosis combined with AECOPD group were lower than those in AECOPD group, RV/Pred% and RV/TLC were higher than those in AECOPD group (P<0.05) . The hospitalization time and cost of the patients with AECOPD were significantly higher than that of the patients with AECOPD (P<0.05) . Conclusion: Compared with AECOPD group, the patients with pneumoconiosis combined AECOPD group had higher infection inflammation level, lower pulmonary function, longer hospitalization time and higher hospitalization cost.
