ABSTRACT
The recommendations on venous thromboprophylaxis have been updated on the basis of current evidence reviewed by a multidisciplinary team. The problem has been approached with regard to its relevance in both surgical and nonsurgical patients. It should be noted that these recommendations were drawn up for use in Spain and, therefore, should be implemented with the drugs and therapeutic practices authorized and generally accepted in this country.
Subject(s)
Venous Thromboembolism/prevention & control , HumansABSTRACT
Un equipo multidisciplinario ha realizado una actualización de recomendaciones en la profilaxis de la enfermedadtromboembólica venosa basándose en las evidencias disponiblesactualmente. Se ha abordado la problemática tanto delpaciente médico como quirúrgico. Hay que puntualizar queesta Normativa está planteada para su utilización en el ámbitode España y, por lo tanto, debe aplicarse con los fármacosautorizados y las prácticas terapéuticas más aceptadasen este país (AU)
The recommendations on venous thromboprophylaxis have been updated on the basis of current evidence reviewed by a multidisciplinary team. The problem has been approachedwith regard to its relevance in both surgical and non surgical patients. It should be noted that these recommendations were drawn up for use in Spain and, therefore, should be implemented with the drugs and therapeutic practices authorized and generally accepted in this country (AU)
Subject(s)
Humans , Evidence-Based Medicine , Thromboembolism/prevention & control , Risk FactorsABSTRACT
No disponible
No disponible
Subject(s)
Pulmonary Embolism/diagnosis , Pulmonary Embolism , Angiography/instrumentation , Angiography , Magnetic Resonance Angiography/methods , Lung/pathology , LungABSTRACT
No disponible
No disponible
Subject(s)
Pulmonary Embolism , Tomography, X-Ray Computed/methods , Angiography/methodsABSTRACT
STUDY OBJECTIVE: To investigate the prognostic significance of a diagnostic delay of greater than 1 week after symptom onset in patients with pulmonary embolism (PE). DESIGN: Prospective cohort study. LOCATION: Emergency Department of Ramón y Cajal Hospital, a 1500-bed tertiary-care center in Madrid, Spain. PATIENTS: Diagnosed with PE by objective testing between January 1, 2003, and June 30, 2005. INTERVENTIONS: All patients received standard anticoagulation therapy during follow-up. ENDPOINTS: Death from any cause or symptomatic recurrent venous thromboembolism (VTE), confirmed by standard objective testing, within 3 months after PE diagnosis. RESULTS: Of the 397 patients with acute PE, 72 (18%) had a diagnostic delay while 325 (82%) did not. The all-cause mortality rate was 13.1% at 3 months (95% CI=9.8-16.4%); due to 9 (12.5%) deaths in the diagnostic delay group and 43 (13.2%) deaths in the group without diagnostic delay (OR 0.9; 95% CI=0.4-2.0). Though multivariate analysis of clinical variables at the time of PE diagnosis identified active cancer, heart failure and immobility for more than 4 days as independent risk factors for death, diagnostic delay was not predictive. Recurrent VTE was observed in 3 (4.2%) of 72 patients with diagnostic delay and in 15 (4.6%) of 325 patients without diagnostic delay (odds ratio: 0.9; 95% CI=0.2-3.2). None of the variables analysed, including diagnostic delay, was associated with an increased risk of recurrent VTE during follow-up. CONCLUSIONS: Among survivors diagnosed with acute PE in the Emergency Department, we did not detect an association between a delay in diagnosis and an increased risk of death or VTE recurrence during the ensuing 3 months of treatment.
Subject(s)
Pulmonary Embolism/diagnosis , Pulmonary Embolism/mortality , Aged , Cohort Studies , Female , Humans , Male , Prognosis , Recurrence , Risk Factors , Time FactorsABSTRACT
No disponible
