ABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Community-Acquired Infections/diagnosis , Tertiary Care Centers , Pneumonia/diagnosis , Community-Acquired Infections/mortality , Pneumonia/mortality , Community-Acquired Infections/therapy , Pneumonia/therapy , Retrospective Studies , Hospitals, University , Spain/epidemiologyABSTRACT
The objective of the study was to validate externally and prospectively the PROFUND index to predict survival of polypathological patients after a year. An observational, prospective and multicenter study was performed. Polypathological patients admitted to an internal medicine or geriatrics department and attended by investigators consecutively between March 1 and June 30, 2011 were included. Data concerning age, gender, comorbidity, Barthel and Lawton-Brody indexes, Pfeiffer questionnaire, socio-familial Gijon scale, delirium, number of drugs and number of admissions during the previous year were gathered for each patient. The PROFUND index was calculated. The follow-up lasted 1 year. A Cox proportional regression model was calculated, and was used to analyze the association of the variables to mortality and C-statistic. 465 polypathological patients, 333 from internal medicine and 132 from geriatrics, were included. One-year mortality is associated with age [hazard ratio (HR) 1.52 95 % CI 1.04-2.12; p = 0.01], presence of neoplasia [HR 2.68 95 % CI 1.71-4.18; p = 0.0001] and dependence for basic activities of daily living [HR 2.34 95 % CI 1.61-3.40; p = 0.0009]. In predicting mortality, the PROFUND index shows good discrimination in patients from internal medicine (C-statistics 0.725 95 % CI 0.670-0.781), but a poor one in those from geriatrics (0.546 95 % CI 0.448-0.644). The PROFUND index is a reliable tool for predicting mortality in internal medicine PP patients.
Subject(s)
Chronic Disease/mortality , Activities of Daily Living , Age Factors , Aged , Aged, 80 and over , Comorbidity , Female , Geriatrics , Hospital Departments , Humans , Internal Medicine , Male , Neoplasms/mortality , Prospective Studies , Spain/epidemiologyABSTRACT
No disponible
