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1.
IEEE Trans Vis Comput Graph ; 29(1): 1102-1112, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36155438

ABSTRACT

With deep learning (DL) outperforming conventional methods for different tasks, much effort has been devoted to utilizing DL in various domains. Researchers and developers in the traffic domain have also designed and improved DL models for forecasting tasks such as estimation of traffic speed and time of arrival. However, there exist many challenges in analyzing DL models due to the black-box property of DL models and complexity of traffic data (i.e., spatio-temporal dependencies). Collaborating with domain experts, we design a visual analytics system, AttnAnalyzer, that enables users to explore how DL models make predictions by allowing effective spatio-temporal dependency analysis. The system incorporates dynamic time warping (DTW) and Granger causality tests for computational spatio-temporal dependency analysis while providing map, table, line chart, and pixel views to assist user to perform dependency and model behavior analysis. For the evaluation, we present three case studies showing how AttnAnalyzer can effectively explore model behaviors and improve model performance in two different road networks. We also provide domain expert feedback.

2.
Sci Rep ; 10(1): 19134, 2020 11 05.
Article in English | MEDLINE | ID: mdl-33154517

ABSTRACT

Computational methods to predict Z-DNA regions are in high demand to understand the functional role of Z-DNA. The previous state-of-the-art method Z-Hunt is based on statistical mechanical and energy considerations about B- to Z-DNA transition using sequence information. Z-DNA CHiP-seq experiment results showed little overlap with Z-Hunt predictions implying that sequence information only is not sufficient to explain emergence of Z-DNA at different genomic locations. Adding epigenetic and other functional genomic mark-ups to DNA sequence level can help revealing the functional Z-DNA sites. Here we take advantage of the deep learning approach that can analyze and extract information from large volumes of molecular biology data. We developed a machine learning approach DeepZ that aggregates information from genome-wide maps of epigenetic markers, transcription factor and RNA polymerase binding sites, and chromosome accessibility maps. With the developed model we not only verify the experimental Z-DNA predictions, but also generate the whole-genome annotation, introducing new possible Z-DNA regions, which have not yet been found in experiments and can be of interest to the researchers from various fields.


Subject(s)
DNA, Z-Form , Deep Learning , Epigenomics , Genomics , Computational Biology , Databases, Genetic , Epigenesis, Genetic , Gene Expression Regulation , Genome , Humans
3.
IEEE Trans Vis Comput Graph ; 26(11): 3133-3146, 2020 Nov.
Article in English | MEDLINE | ID: mdl-31199260

ABSTRACT

We present an interactive visual analytics system that enables traffic congestion exploration, surveillance, and forecasting based on vehicle detector data. Through domain expert collaboration, we have extracted task requirements, incorporated the Long Short-Term Memory (LSTM) model for congestion forecasting, and designed a weighting method for detecting the causes of congestion and congestion propagation directions. Our visual analytics system is designed to enable users to explore congestion causes, directions, and severity. Congestion conditions of a city are visualized using a Volume-Speed Rivers (VSRivers) visualization that simultaneously presents traffic volumes and speeds. To evaluate our system, we report performance comparison results, wherein our model is more accurate than other forecasting algorithms. We demonstrate the usefulness of our system in the traffic management and congestion broadcasting domains through three case studies and domain expert feedback.

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