Aesthetic Correction Using an Auricular Conchal Cartilage Graft and LASER for Nostril and Vestibular Stenosis / 대한이비인후과학회지

Stenosis of the nostril is a rare deformity. The most common etiology is trauma. Iatrogenic trauma is a significant contributor; examples being prolonged nasal packing under tension, chemical cauterization, or other nasal procedures. Other causative factors include congenital malformations and infections. This deformity is considered a challenging problem because of frequent relapses and unsatisfactory corrections. The standard technique by which this deformity is reconstructed is by excision of the cicatrical stenosis and insertion of a split-thickness skin autograft over a mold. This technique will enlarge the nostril but will not correct the narrowing of the vestibular stenosis and nasal valve area. So, nasal obstruction symptoms remain. This paper describes a case of nostril and vestibular stenosis in a 58-year-old woman that was corrected successfully in a single stage. In this paper, not only nostril but also vestibular stenosis and nasal valve area narrowing were properly reconstructed by using an auricular conchal cartilage graft, LASER excision, and a nostril stent. The following is a report on this research.

A Case of Anaplastic Carcinoma Arising in Thyroglossal Cyst / 대한이비인후과학회지

A thyroglossal cyst is a common midline mass, which is related to the hyoid bone, and it may show signs of inflammation. Carcinoma arising in the thyroglossal cyst is rare, accounting for less than 1% of all thyroglossal cysts. Papillary adenocarcinoma is the most common histologic type(75-85%), whereas anaplastic carcinoma arising in thyroglossal cyst is extremely rare and there has been only two reported cases of it. Its prognosis is not established due to its rarity. We experienced a case of anaplastic carcinoma that occured in a thyroglossal cyst in a 63-year-old man and report it.

Hemostatic Efficacy of Topical Application of Cold Hydrogen Peroxide in Adenoidectomy / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Adenoidectomy is one of the most common procedures in the field of otolaryngology, and various hemostatic agents and techniques have been used for stanching the wound of adenoidectomy site. The aim of this study is to evaluate the hemostatic efficacy of topical application of cold hydrogen peroxide in adenoidectomy. MATERIALS AND METHOD: We randomly divided 120 candidates (aged 3-14 years) for adenoidectomy into 4 groups, and 3% hydrogen peroxide (3+/-2degrees C), 3% hydrogen peroxide (20+/-2degrees C), 0.05% epinephrine solution (3+/-2degrees C) and 0.05% epinephrine solution (20+/-2degrees C) were applied topically to each group respectively. The time consumed for bleeding control, and the hemostatic findings of adenoidectomy wound at 5 minutes after curretage, 6 hours after operation of each group were compared. RESULTS: The use of cold hydrogen peroxide significantly reduced intraoperative time when compared with uisng other hemostatic agents. And in the adenoidectomy site, it is found that the incidence of oozing and active bleeding decreased when cold hydrogen was applied. CONCLUSION: Cold hydrogen peroxide is a useful agent for hemostasis in adenoidectomy.

Two Cases of Pilomatrixoma in Neck / 대한이비인후과학회지

Pilomatrixoma or calcifying epithelioma is a rare benign tumor arising from hair cortex cell or hair follicle of sebaceous glands. But because of it's characteristic clinical presentation, practitioners should be aware of it's clinical feature. Most frequently, the tumor presents as a superficial located solitary, rock hard and noninvasive cutaneous mass on the face, neck or upper extrimities, that is often accompanied by reddish-blue discoloration of the overlying skin. It usually occurs within the first two decades of life. Recently, we experienced two cases of pilomatrixoma in the head and neck, which was diagnosed by histopathologic examination. The tumor was successfully removed by complete resection. So we report two cases with a review of literature.

Functional Differences of the Lymphocytes in Nasal Polyps between Allergic and Non-Allergic Patients

Lymphocytes can produce various kinds of cytokines which are responsible for the development of the infectious and allergic inflammation. We focused on the role of the lymphocyte in the pathogenesis of the nasal polyp. This study was designed to evaluate the functional differences of the lymphocytes between allergic and non-allergic polyp. Lymphocytes were obtained from peripheral blood and tissues of polyp in 12 patients with non-allergic polyp, 7 patients with allergic polyp and 5 normal subjects as control. Cytokines were measured with ELISA from each group of lymphocytes after stimulation with Concanavalin A (Con A). We compared the production of interleukin (IL)-2, IL-4, tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma between the non-allergic and allergic groups. The levels of IL-4 and IL-6 from polyp tissue lymphocytes were higher in allergic group, while those of IL-2 and IFN-gamma were higher in non-allergic group. The levels of IL-4, IL-6 and TNF-alpha from peripheral blood lymphocytes were higher in allergic group, and IFN-gamma was higher in non-allergic group. These results suggest that cytokine productivity of the polyp tissue lymphocytes appear to be parallel to that of the peripheral blood lymphocytes in each group and shows distinct pattern of ytokine production between two groups.