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2.
Clin Exp Dermatol ; 46(6): 1097-1101, 2021 Aug.
Article in English | MEDLINE | ID: mdl-33713349

ABSTRACT

Azathioprine is an immunosuppressant drug used in many dermatological and nondermatological pathologies. Azathioprine hypersensitivity syndrome (AHS) is a rare idiosyncratic reaction that is not related to dose or thiopurine methyltransferase activity. Up to half of cases of AHS can present with variable cutaneous manifestations besides fever, malaise and other systemic symptoms. It is important to be aware of AHS, as continuance or reintroduction of the drug can led to multiorgan failure and cardiovascular collapse.


Subject(s)
Azathioprine/adverse effects , Drug Hypersensitivity Syndrome/etiology , Drug Hypersensitivity Syndrome/pathology , Immunosuppressive Agents/adverse effects , Skin/pathology , Diagnosis, Differential , Edema/pathology , Humans , Male , Middle Aged , Neutrophils/pathology
3.
Clin Exp Dermatol ; 44(1): 96-98, 2019 Jan.
Article in English | MEDLINE | ID: mdl-29851125

ABSTRACT

A young woman presented with a perianal nodular lesion, which was found to have histopathological findings of hidradenoma papilliferum. The anal skin is an uncommon location for this neoplasm.


Subject(s)
Sweat Gland Neoplasms/pathology , Tubular Sweat Gland Adenomas/pathology , Adult , Female , Humans , Perineum/pathology
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