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Ophthalmologica ; 220(6): 406-8, 2006.
Article in English | MEDLINE | ID: mdl-17095889

ABSTRACT

A case of early-onset sclerolimbal ectasia following low-dose topical mitomycin C application during uveitic glaucoma surgery is reported. Intraoperative and postoperative clinical courses were consistent with sclerolimbal ectasia. Adjunctive utilization of intraoperative low-dose 0.02% mitomycin C for the management of chronic uveitic glaucoma patients who are under concomitant systemic immunosuppressive regimen may enhance the risk of subacute postoperative sclerolimbal ectasia. Mitomycin C concentrations < 0.02%, decreased scleral exposure time, and a strict informed consent policy are strongly recommended in this subset of uveitic patients.


Subject(s)
Alkylating Agents/adverse effects , Corneal Diseases/chemically induced , Glaucoma, Open-Angle/therapy , Mitomycin/adverse effects , Scleral Diseases/chemically induced , Trabeculectomy , Uveitis, Anterior/therapy , Adolescent , Alkylating Agents/administration & dosage , Combined Modality Therapy , Dilatation, Pathologic/chemically induced , Glaucoma, Open-Angle/drug therapy , Glaucoma, Open-Angle/surgery , Humans , Intraocular Pressure , Male , Mitomycin/administration & dosage , Uveitis, Anterior/drug therapy , Uveitis, Anterior/surgery
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