ABSTRACT
A retrospective review was conducted on 13 patients with esthesioneuroblastoma (ENB), treated at our institution from 1977 to 1997. According to the Kadish classification, one patient was in stage A, 5 patients were classified as stage B and 7 patients were in stage C. Five-year disease-specific survival was found to be 51%. Forty-six percent of the patients experienced relapse and despite intensive salvage therapy, median survival after recurrences was only 12 months. This indicates the need for good primary control in local as well as distant disease. The role of pre- versus postoperative radiotherapy to secure good local control is discussed and compared with the literature, and treatment guidelines are proposed. The tumours were graded according to the Hyams' classification and its importance as a prognostic factor is briefly discussed.
Subject(s)
Esthesioneuroblastoma, Olfactory/radiotherapy , Esthesioneuroblastoma, Olfactory/surgery , Nasal Cavity/pathology , Nose Neoplasms/radiotherapy , Nose Neoplasms/surgery , Adolescent , Adult , Aged , Disease-Free Survival , Esthesioneuroblastoma, Olfactory/pathology , Female , Humans , Male , Middle Aged , Neoplasm Staging , Nose Neoplasms/pathology , Prognosis , Radiotherapy, Adjuvant , Retrospective Studies , Salvage Therapy , Treatment OutcomeABSTRACT
Four hundred fifteen patients with laryngeal cancer were treated mainly by primary irradiation from 1965 to 1983, at the Radium Centre of Odense. By December 31, 1983, a total of 32 patients had developed pulmonary cancer. The Danish Cancer Registry calculated the expected number of pulmonary cancer in a population of the same composition from the same period of time and the same geographical locale. A statistically significant hyperfrequency of pulmonary cancer among males was found, most pronounced among supraglottic cases: 6.73. Furthermore, a cumulative estimation of the risk of developing pulmonary cancer as a function of follow-up revealed a risk of 26% during the first 14 years of follow-up. The only effective way to solve the problem is to stop smoking.
Subject(s)
Laryngeal Neoplasms/therapy , Lung Neoplasms/epidemiology , Neoplasms, Multiple Primary , Denmark , Follow-Up Studies , Humans , Risk , Sex Factors , Time FactorsABSTRACT
A case of volvulus of the transverse colon in a patient with dystrophia myotonica is reported in which the volvulus was reduced during colonoscopy. Indications for colonoscopy in patients with volvulus of the transverse colon are discussed, and it is suggested that colonoscopic reduction of volvulus of the transverse colon might have a place as emergency treatment in patients with other severe complications.
