ABSTRACT
Despite the high acceptability of Allium sativa (Garlic) as a remedy for many diseases as earlier stated by manyresearchers, previous studies have shown that chronic and unregulated consumption of garlic may result to intra vascularhaemolytic anaemia in rats. The present study was conducted to examine the effect of crude extract of garlic on microscopicstatus of red blood cells and some other haematological indices of normal albino rats. The animals were grouped into two;group 1 were normal animals treated with water while group 2 were normal animals administered 150mg/kg body weight ofcrude extract of garlic on alternate days for three weeks. At the end of three weeks treatment, blood samples obtained fromthe tail vein of the rats were used for haematological indices and erythrocyte morphology. The values obtained wereexpressed as Mean± SEM and compared using student t test. The results showed that there was no significant difference inthe PCV which was 43.20 ± 0.80% and 45.00 ± 0.36% in both control and experimental groups respectively. However, theRBCs were significantly decreased (P< 0.05) from 166.80 ± 3.44 x106 µL-1 in the control group to 87.80 ± 9.34 x106 µL-1 inthe treatment group. The percentage reticulocyte counts on the other hand significantly increased from 2.60±4.25% in controlgroup to 11.20± 16.4% in treated group. Fragmented RBCs with a lot of schistocytes with adequate platelets were seen onperipheral blood film of crude garlic treated rats as compared to control. Our results suggested intravascular haemolysis andnumerous reticulocytes on blood film confirmed our view on bone marrow response. The presence of schistocytes andacanthocytes may be an indication that the liver is involved in the observed effect.
Subject(s)
Antioxidants/pharmacology , Erythrocyte Count , Erythrocytes/drug effects , Plant Extracts/pharmacology , Animals , Body Weight , Erythrocyte Count/methods , Hemolysis/drug effects , Male , Rats, Wistar , Reticulocyte Count/methods , Vegetables/drug effectsABSTRACT
Research on screening for intimate partner violence (IPV) within health care in a sub-Saharan African context is rare. This paper assessed factors associated with the readiness to screen for IPV among care providers (HCP, n = 274) at Kano hospital, Nigeria. Readiness was measured using the Domestic Violence Health Care Providers' survey instrument, which measures grade of perceived self-efficacy in screening for IPV, fear for victim/provider safety, access to system support to refer IPV victims, professional roles resistant/ fear of offending clients, and blaming the victim for being abused victim. Social workers perceived a higher self-efficacy and better access to system support networks to refer victims than peers in other occupation categories. Female care providers and doctors were less likely to blame the victim than males and social workers, respectively. Younger care providers of Yoruba ethnicity and social workers were less likely to perceive conflicting professional roles related to screening than older providers of Hausa ethnicity and doctors, respectively. Implications of our findings for interventions and further research are discussed.
Subject(s)
Attitude of Health Personnel , Health Personnel/statistics & numerical data , Mass Screening/statistics & numerical data , Professional-Patient Relations , Spouse Abuse/diagnosis , Spouse Abuse/statistics & numerical data , Adult , Female , Humans , Male , Mass Screening/organization & administration , Middle Aged , Nigeria/epidemiology , Patient Acceptance of Health Care/psychology , Physician's Role , Primary Health Care/organization & administration , Risk Factors , Socioeconomic Factors , Spouse Abuse/prevention & control , Surveys and Questionnaires , Young AdultABSTRACT
A pilot study of violent injury surveillance was implemented in two hospitals in Kano, Nigeria, in two phases: a formative evaluation including training and arranging the collection of hospital information, followed by a 6 month prospective data collection. Road traffic injuries constituted about 80 per cent of the cases, gunshot injuries were the commonest in victims of interpersonal violence (IPV). The causes and context of IPV, the relationship of victims and perpetrators, and the place, related activities and anatomical site of injuries from IPV are summarized.
Subject(s)
Hospitalization , Population Surveillance , Violence/prevention & control , Wounds and Injuries/epidemiology , Accidents, Traffic/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Data Collection , Female , Humans , Infant , Infant, Newborn , Male , Middle Aged , Nigeria/epidemiology , Pilot Projects , Prospective Studies , Risk Factors , Violence/statistics & numerical data , Wounds and Injuries/prevention & control , Young AdultABSTRACT
A multinational injury surveillance pilot project was carried out in five African countries in the first half of 2007 (Democratic Republic of the Congo, Kenya, Nigeria, Uganda and Zambia). Hospitals were selected in each country and a uniform methodology was applied in all sites, including an injury surveillance questionnaire designed by a joint programme of the Pan American Health Organization and the United States Centres for Disease Control and Prevention. A total of 4207 injury cases were registered in all hospitals. More than half of all injury cases were due to road traffic accidents (58.3%) and 40% were due to interpersonal violence. Self-inflicted injuries were minimal (1.2% of all cases). This report provides an assessment of the implementation of the project and a preliminary comparison between the five African countries on the context in which inter-personal injury cases occurred. Strengths and weaknesses of the project as well as opportunities and threats identified by medical personnel are summarized and discussed. A call is made to transform this pilot project into a sustainable public health strategy.
